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Little Known Glomalin, a Key Protein in Soils

If you had heard of glomalin, you are a better person than I am. Until a couple of months ago I wasn’t aware of its existence, which is close to sinful: it happens to be a very abundant protein in the soil rhizosphere, playing a key role in the soil’s mechanical properties and as repository of s... Read More

The Ins and Outs of Gut Bacteria

Deep in the bowels of our, well, bowels, lurk trillions of microscopic bacteria. But don't be fooled by the big bad "B" word, intractably tied to infections and disease. In fact, these bitty bugs do us a world of good.

"There's a certain 'ick' factor associated with gut bacteria," said Lita P... Read More

Tricky Trichy

Trichomonas vaginalis is a protozoan parasite of the urogenital tract in men and women and causes a sexually transmitted disease, trichomoniasis, in about half of infected women. Infections are associated with pelvic inflammatory disease, adverse pregnancy outcomes, infertility, an increased inc... Read More

Ground Turkey Study Finds More Than Half Of Samples Contaminated With Fecal Bacteria

More than half of ground turkey samples are contaminated with fecal bacteria, according to a new study from Consumer Reports. In addition, the magazine found that more than 90 percent of the ground turkey samples it tested contained at least one of the five bacteria the test was looking for -- s... Read More

Fighting the Impact of Antibiotic-Resistant Bacteria

The resistance of bacteria to antibiotics and similar drugs—called antimicrobials—is considered a major public health threat by the Food and Drug Administration (FDA) and its counterparts around the world.

Antibiotics have transformed health care since they were introduced in the 1940s and ha... Read More

Research project studies fungi found in popular drink

A research project at Indiana State University into a popular packaged drink has found five types of fungus. Kathleen Dannelly, associate professor microbiology, said one previous study published online found only one fungus in Capri Sun, the popular drink manufactured by Kraft. However, the res... Read More

Protein improves efficacy of tumor-killing enzyme

Researchers at NIAID have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio this week, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the ins... Read More

Dangerous Rendezvous

A macrophage (pale brown) interacts with Borrelia cells (blue), the spirochete bacteria that cause Lyme disease. Although the outer membrane of Borrelia contains a strong antigen, the OspC protein, the bacterium successfully evades the human immune system by hiding out in places less accessible ... Read More

Gene therapy: 'Heart-healing virus' trial starts

Patients in the UK have been enrolled into a trial to see if an engineered virus can be used to heal their damaged and struggling hearts. The trial will use a virus to introduce genetic material into heart muscle to reverse the organ's decline. The British Heart Foundation said the idea had "gre... Read More

The Art of Microbial Alchemy

In 2001, Kashefi and collaborators published an article in Applied and Environmental Microbiology reporting the surprising finding that several iron-reducing microbes can use gold as an electron acceptor for their respiration. These microbial alchemists included both mesophilic and thermophilic ... Read More

Bacteria help trace how alcohol binds to brain

Bacteria that grows only on rocks in the Swiss Alps has helped researchers identify how alcohol might affect key brain proteins.

“Now that we’ve identified this key brain protein and understand its structure, it’s possible to imagine developing a drug that could block the binding site,” says ... Read More

Thymus Teaches Immune Cells to Ignore Vital Gut Bacteria

The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say.

When immune cells recognize essential gut bacteria as foreign, inflammatory bowel disease such as ulcerative colitis and Crohn's disease can be ... Read More

Going viral on Science Sunday Hangout on Air

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.


{youtube}WpLH4gRk9gc{/youtub... Read More

Hospitals see surge of superbug-fighting products

They sweep. They swab. They sterilize. And still the germs persist.

In U.S. hospitals, an estimated 1 in 20 patients pick up infections they didn't have when they arrived, some caused by dangerous 'superbugs' that are hard to treat.

The rise of these superbugs, along with increased pressur... Read More

How Parkinson's Disease Protein Acts Like a Virus

A protein known to be a key player in the development of Parkinson's disease is able to enter and harm cells in the same way that viruses do, according to a Loyola University Chicago Stritch School of Medicine study.

The protein is called alpha-synuclein. The study shows how, once inside a ne... Read More

BacterioFiles Micro Edition 123 - Proteobacteria Protonate Poison

This episode: Soil microbe has a good enzyme for degrading cyanide pollution!




Download Episode (4.2 MB, 4.5 minutes)


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A Potential Way to Eat Eggs Without Dying

Bacteria are all over us, inside and out. Jiri Hulcr recently found 1,458 species of bacteria "new to science" in a small sample of human belly buttons. What we know about our little passengers and how they affect our bodies is dwarfed by what we do not. That can be disconcerting to think about,... Read More

Three wrongs make a right

Pancreatic cancer is a dreadful disease. Even in rich countries, only about 4% of those diagnosed with it are still alive after five years. In America it is the third-most-common cause of cancer deaths among women, after lung and breast cancer; among men it is fourth, after lung, prostate and co... Read More

TWiV 230: Gene goes to Washington, flu chickens out



Hosts: Vincent Racaniello, Rich Condit, Read More

Mutant version of H5N1 flu virus found to be more preferential to human infection

In its native state, according to the CDC, the H5N1 flu virus is highly contagious and is especially deadly to birds. Fortunately, few people have contracted this strain of flu as it's quite deadly in people as well. Luckily, there have been very few cases of transmission of the virus between pe... Read More
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