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Cloning competition drives student and mentor excellence

Mentoring scientific teams in a project-oriented competition, like engineers can do through the ASCE Concrete Canoe National Competition or the SAE Supermileage Competition, is rare in the microbial sciences. Mentoring a team through this experience allows scientists impart different skills than... Read More

TWiM #144: Did eukaryotes invent anything?

The TWiMers discuss how changes in domestic laundering affect the removal of microorganisms, and assembly of a nucleus-like structure during viral replication in bacteria.


Hosts: Vincent Racaniello, Read More

Multivalent vaccines may help prevent future outbreaks

The Coalition for Epidemic Preparedness Innovation (CEPI) hopes to prevent future outbreaks by generating, testing, and storing vaccines before outbreaks occur. How do you design a vaccine before a prevailing serotype is determined? Read More

BacterioFiles 284 - Remedies Reduce Recipient Rejection

This episode: Modifying mice's microbial communities increased mouse survival before a transplantation was rejected by their immune system!


(9.6 MB, 10.5 minutes)


Show notes: 


Read More

Feed a cold, starve a fever? Not so fast, according to Salk research

The last time you had a stomach bug, you probably didn’t feel much like eating. This loss of appetite is part of your body’s normal response to an illness but is not well understood. Sometimes eating less during illness promotes a faster recovery, but other times—such as when cancer patients exp... Read More

TWiM 144 Letters

Kayla writes:


Hey there TWIM team


I am a Veterinary Microbiologist in Cork in Ireland!


Long time listener of all the TWIX series and I love everyone of them.


I work in a diagnostic lab in cork and the only thing that gets me through the day is ... Read More

TWiV 426: I'm Axl, and I'll be your cervid today

The sages of TWiV explain how chronic wasting disease of cervids could be caused by spontaneous misfolding of prion protein, and the role of the membrane protein Axl in Zika virus entry into cells.


Hosts:  Read More

BacterioFiles 285 - Sultry Snow Cell Sun Screen

This episode: Algae growing in Arctic snow make red pigments that heat up their surroundings!


(6.8 MB, 7.5 minutes)


Show notes: 


Ne... Read More

Antibiotics, not dirty hospitals, the main cause of C. difficile epidemic Share

Restricting the use of a common antibiotic was more important than a high profile 'deep clean' of hospitals in massively reducing UK antibiotic resistant Clostridium difficile (C. diff) cases, a major new study has found.

The study concluded that overuse of antibiotics like ciprofloxacin led... Read More

Interlab Reproducibility in Bacterial Genotyping by Whole-Genome Sequencing

One of the most important aspects of a new laboratory protocol is its reproducibility (as previously discussed on ASM’s Microbial Sciences blog). A protocol must produce the same results when performed by different scientists at different labs, and this is especially important when considering n... Read More

BacterioFiles 286 - Prokaryote Prevents Pregnancy Pathogen

This episode: Bacteria in mosquito cells can block transmission of Zika virus!


(8.1 MB, 8.9 minutes)


Show notes: 


News item
Read More

Microbiomes more in flux in patients with inflammatory bowel disease

Patients with inflammatory bowel disease are more likely to see dramatic shifts in the make-up of the community of microbes in their gut than healthy people, according to the results of a study published online Feb. 13 in Nature Microbiology.

While scientists have known that there are differe... Read More

Beautiful Bacillus III

At the start of each semester students do environmental swabs. This was a swab taken form the bottom of a shoe incubated for 48 hrs at 37 degrees C then held at room temp for 48 hrs then held at refrigerated temp's. Seen is a beige matt colony, rhizoid and raised in the center, mucoid in the cen... Read More

Melioidosis: The Most Neglected Tropical Disease

The ASM Biothreats conference covers preparation for, handling during, and analysis of infectious disease outbreaks, and includes session on research, response, and policies on biological threats and emerging infectious diseases. Most sessions cover broad topics such as emergency preparedness, v... Read More

TWiV 429: Zika Experimental Science Team

Vincent meets with members of team ZEST at the University of Wisconsin Madison to discuss their macaque model for Zika virus pathogenesis.


Hosts: Vincent Racaniello Read More

TWiV 427: It was a DURC and UV light

The TWiVoids discuss the March for Science, the GOF moratorium, and a classic virology paper on mapping the gene order for vesicular stomatitis virus.


Hosts: Vincent Racaniello Read More

TWiM #145: Anything but Academic

Vincent meets up with Catharine Bosio, Michael Merchlinsky, and Shilpa Gadwal at the ASM Biothreats meeting to talk about careers for scientists outside of the ivory tower.


Host: Vincent Racaniello


... Read More

Beautiful Bacillus IIII

At the start of each semester students do environmental swabs. This was a swab taken form the bottom of a shoe incubated for 48 hrs at 37 degrees C then held at room temp for 48 hrs then held at refrigerated temp's. Seen is a beige matt elongated (not circular) colony, rhizoid and raised in the ... Read More

TWiV 428: Lyse globally, protect locally

The TWiVsters explain how superspreader bacteriophages release intact DNA from infected cells, and the role of astrocytes in protecting the cerebellum from virus infection.


Hosts: Vincent Racaniel... Read More

Microbial polyesterase genes may help sustainable textile biodegradation

Good news for sustainable textiles of the future was announced in a recent Applied and Environmental Microbiology report that described the discovery of microbial polyesterase genes. The study described the discovery and characterization of new enzymes from microbial communities associated with ... Read More
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