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Groups moving forward to develop AIDS gel

Groups developing a gel to protect women from the AIDS virus say they are moving ahead to develop the product that was hailed as "groundbreaking" after a study on its effectiveness was released in July.

The developers, who met last week with the U.S. Food and Drug Administration, said the FDA... Read More

Scientists Helping Keep in-Demand Smoked Salmon Safe to Eat, Thanks to New Mathematical Model

Scientists with the U.S. Department of Agriculture (USDA) are helping ensure that the smoked salmon that's always a hit at festive gatherings also is always safe to eat, including among their achievements the development of a first-of-its-kind mathematical model that food processors and others c... Read More

Superbug infection in Brazil hospitals kills 18

Eighteen people have died in the Brazilian capital after contracting a hospital superbug.

They were infected with bacteria which produce the enzyme Klebsiella pneumoniae Carbapenemase (KPC), which renders most modern antibiotics ineffective.

It tends to infect hospitalised people whose imm... Read More

Alemtuzumab Raises CMV Infection Risk

Cytomegalovirus (CMV) infection in kidney or kidney/pancreas transplant recipients occurs more frequently when alemtuzumab is used for induction instead of antithymocyte globulin (ATG), according to a new study from the University of Minnesota in Minneapolis.

In addition, in alemtuzumab recip... Read More

Africa to launch mass polio vaccination campaign

The World Health Organization on Tuesday announced a mass polio vaccination campaign in Africa, the same day Ugandan health officials announced an outbreak of the highly infectious disease.

WHO officials in Geneva said the 15-country campaign would start as early as next week in Angola and Co... Read More

Haiti capital braced for cholera

While the cholera outbreak that has so far killed 259 in Haiti is starting to taper off, the capital Port-au-Prince is bracing itself for the disease's arrival. Can treatment reach people in time to prevent more deaths?

Emergency supplies of clean water, soap and water-purifying equipment con... Read More

Proteins get the glory, but are non-protein-coding RNAs doing the work?

When it comes to biology, the proteins get all the glory. A new study coming out in mBio might change this, though: the results show that, in the immune response, non-protein-coding RNAs may deserve some credit for what they do, too.
Peng et al. used whole transcriptome analysis in mice to e... Read More

Journal of Bacteriology authors have sequenced 13 different strains of Borrelia burgdorferi, the bacteria that cause Lyme disease, the most common tickborne disease in North America.

Press release from National Institute of Allergy and Infectious Diseases (NIAID) on the significance a Genome Announcement by Steven E. Schutzer, Claire M. Fraser-Liggett, Sherwood R. Casjens, Wei-Gang Qiu, John J. Dunn, Emmanuel F. Mongodin, and Benjamin J. Luft published ahead of print in the... Read More

Respiratory virus infection triggers new class of biomolecules

For the first time, scientists have discovered that a poorly understood class of RNA produced in a mammal's cells during a respiratory virus attack may affect the outcome of the infection. Their findings are reported today in mBio, a journal of the American Society for Microbiology.

RNA (ribo... Read More

New Strategy to Kill Bugs -- Even Those in Hiding

New strategies to apply antibiotics more effectively to hibernating bugs have been developed by researchers at the University of Hertfordshire.

In a paper, which appeared this month in the Institute of Electrical and Electronics Engineers (IEEE) Transactions on Evolutionary Computing, Dr Ole ... Read More

Listeria 'tricks' cells to infect humans

Listeria bacteria, a source of food-borne illness, tricks cells in the body's intestines to pass through those cells and make people sick, researchers say.

Researchers at Purdue University found that listeria, even in low doses, somehow triggers intestinal cells to express a protein that acts... Read More

China reports first cases of NDM-1 super bacteria infection

China's health authorities Tuesday announced the country's first three cases of NDM-1, a multi-drug resistant super bacteria.

Chinese Center for Disease Control and Prevention (China CDC) official Ni Daxin said at a press conference that two cases were detected from samples submitted by the l... Read More

Frog prince sensor fights bacteria

A newly developed sensor may revolutionize how drugs and medical devices are tested for contamination.

In the process it may also help ensure the survival of two species of threatened animals. To be fair, some of the credit goes to an African frog.

In the wild, the African clawed frog pro... Read More

TWiP 18: Cryptosporidium

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Vincent and Dickson discuss the intracellular parasite Cryptosporidium, which causes diarrheal disease in most mammalian species.

Download  Read More

TWiP 18 Letters

Avery writes:

Hello Doctors,

In episode #1 of Twip Dr. Despommier mentioned the gap between protozoans and nematodes with respect parasitism. I wonder if this claim takes into account the fish parasite Buddenbrockia plumatellae. Because its body is vermiform... Read More

Haiti says cholera deaths slow, now at 259

The rate of deaths in Haiti's cholera epidemic slowed on Monday, officials said, as a multinational medical operation ramped up to curb an outbreak that has killed 259 people in the earthquake-hit country.

After several days in which fatalities had numbered dozens each day, only six deaths we... Read More

New study casts doubt on retrovirus link to cancer and chronic fatigue syndrome

A new study casts further doubt on the role of a retrovirus, XMRV, in human disease, adding weight to the possibility that earlier studies finding a link between the virus and cancer and chronic fatigue syndrome may have been wrong.

In the study, researchers from the National Cancer Institute... Read More

Giant virus with tiny victims carries a monster genome

A giant virus that infests microscopic sea creatures has the largest genome of any marine virus, and the second largest of any virus. Its genome includes a host of genes not normally found in viruses, lending support to claims that viruses had a critical role in the evolution of complex life.

... Read More

Winning image of mosquito heart could help us fight malaria

A fluorescent image of the heart of a mosquito taken by a Vanderbilt graduate student has captured first place in Nikon’s “Small World” 2010 photomicrography competition.

Jonas King took the image that shows a section of the tube-like mosquito heart magnified 100 times. He is a member of the ... Read More

Penn study identifies molecular guardian of cell's RNA

When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding gene sequences are removed and the remaining protein-coding sequences ar... Read More
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