The Coalition for Epidemic Preparedness Innovation (CEPI) hopes to prevent future outbreaks by generating, testing, and storing vaccines before outbreaks occur. How do you design a vaccine before a prevailing serotype is determined? Read More
In 2014, before the FIFA World Cup opened in Brazil, there were fears that many of the 600,000 foreign visitors expected for the world's largest soccer tournament would acquire dengue fever. Their numbers could reach hundreds or even thousands, according to some predictions. Read More
Scientists have discovered the mechanism that hijacks the immune system's response to tuberculosis, revealing an important new drug target for the disease that kills more than 1 million people each year.
Herman Sintim, Purdue University's Drug Discovery Professor of Chemistry, collaborated wi... Read More
Russian President Vladimir Putin claimed Wednesday his country had developed a vaccine for the Ebola virus which has killed thousands of people in west Africa.
But Putin, who is famed for his talent for headline-grabbing announcements, did not give any name for the vaccine, nor did he say how... Read More
A family of highly drug-resistant and potentially deadly bacteria may be spreading more widely—and more stealthily—than previously thought, according to a new study from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.
Researchers examined carbapenem resi... Read More
Sharon and Scott join the TWiV team to talk about their work on dengue antibody-dependent enhancement of Zika virus infection, and identifying the virus in mosquitoes from Miami.
Montreal, April 28, 2016 - An outbreak of an intestinal parasite common in the tropics, known as Cryptosporidium, has been identified for the first time in the Arctic. The discovery was made in Nunavik, Quebec, by a team from the Research Institute of the McGill University Health Centre (RI-MUHC... Read More
Aedes mosquitoes carrying the bacterium Wolbachia--found inside the cells of 60 percent of all insect species--are drastically less able to transmit Zika virus, say researchers at Brazil's Oswaldo Cruz Foundation (FIOCRUZ) in a study published May 4 in Cell Host & Microbe. Read More
If you live with pets, you know where their tongue has been, yet you let them kiss and lick you all they want without even thinking twice about it. I've heard people say that a dog's mouth is very clean, and that their saliva, delivered by licking, can help heal wounds, but is that really true?
... Read More
Have you ever gone to the beach, ready for a day of sun and sand, only to find a warning sign? One of the most common reasons beaches close is due to the presence of coliform bacteria. These indicator bacteria, such as Escherichia coli, are used as markers for fecal waste, since their presence c... Read More
In fall 2015, a new human hepegivirus (HHpgV-1) was identified by using a novel, high throughput sequencing technique. Concerns were raised that this virus was found in blood to be used for transfusions, potentially passing on the infection. But without tools to test for its presence, there was ... Read More
A new commentary from Patrick McNamara and Stuart Levy cautions that the Food and Drug Administration’s ban on triclosan and 18 other biocidal chemicals that promote antibiotic resistance is only a starting point. Triclosan’s long-term impact, as well as the risks substitute chemicals may pose, ... Read More
Imitation may be the sincerest form of flattery, but it can also be the easiest way to make a buck. That’s the primary motivation for camouflaging within an already-established brand: Sunbucks, McDowell’s, and Mountain Lightening all rely on brand recognition – of a brand that isn’t their own. W... Read More
The TWiVome discuss the blood virome of 8,420 humans, and thoroughly geek out on a paper about the number of parental viruses in a plaque.
Microbiome research has revealed that there are good guy and bad guy bacteria living together in complex communities on our skin, in our mouths, throughout our guts and pretty much everywhere in between. But what do you call a good guy bacterium that is aiding and abetting a disease culprit?
... Read More
Researchers with the Iowa City VA Health Care System and University of Iowa have produced striking new evidence of neutrophil plasticity, or the ability of these white blood cells to change their properties.
The scientists exposed neutrophils—the most prevalent white blood cells—to Helicobact... Read More
The last time you had a stomach bug, you probably didn’t feel much like eating. This loss of appetite is part of your body’s normal response to an illness but is not well understood. Sometimes eating less during illness promotes a faster recovery, but other times—such as when cancer patients exp... Read More
Oh I hope I win!
Hi TWIM Team
Investigators from the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used the revolutionary new gene-editing technology CRISPR-Cas9 to identify three promising new targets for treatment of HIV infection. In their report receiving advance online publicati... Read More