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Prion disease detected soon after infection and in surprising place in mouse brains

Prion diseases--incurable, ultimately fatal, transmissible neurodegenerative disorders of mammals--are believed to develop undetected in the brain over several years from infectious prion protein. In a new study, National Institutes of Health (NIH) scientists report they can detect infectious pr... Read More

Long Distance Travelers Likely Contributing to Antibiotic Resistance's Spread

Washington, DC – August 20, 2015 - Swedish exchange students who studied in India and in central Africa returned from their sojourns with an increased diversity of antibiotic resistance genes in their gut microbiomes. The research is published 10 August in Antimicrobial Agents and Chemotherapy, ... Read More

1977 H1N1 influenza virus is not relevant to the gain of function debate

The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More

TWiP 105: Survival of the fattest

The TWiPanosomes solve the case of the Young Man from Anchorage, and discuss how cestode parasites increase the resistance of brine shrimp to arsenic toxicity.


Hosts: Vincent Racaniello Read More

Brown University to help Ghana build HIV, TB research capacity

PROVIDENCE, R.I. [Brown University] -- Tuberculosis is the leading cause of death among HIV-positive Ghanaians, with one study blaming TB for 57 percent of HIV-related deaths in the mid-sized West-African nation. To tackle the problem, a partnership between Brown University and the University of... Read More

ANTIBIOTICS DON’T POP BACTERIA LIKE A BALLOON

The days when antibiotics worked reliably and scientists could assume they worked directly—like popping a balloon—are fading. As resistance mounts, understanding how antibiotics really work could be the key to sustaining their efficacy. Read More

TWiP 99 letters

 


Mark writes:


Temperature in Oklahoma is 12 degrees C today and rainy.


My guess is Tunga penetrans which is native to South America. The black point at center of itchy toe lesion is the flea which are legs, spiracles and egg laying aparatus. Fema... Read More

BacterioFiles 252 - Small Cells Supervise Circadian Cycles

This episode: In mice, high-fat diets affect their gut microbes, which in turn disrupts their circadian cycles and metabolic health!


(8.6 MB, 9.35 minutes)


Show notes: 
Read More

GUT TRANSIT TIME CHANGES WITH ‘TRAVELER’S DIET’

To better understand the importance of gut bacteria in human health, researchers measured the time it takes food to move through the gastrointestinal tract, called gut motility, in mice—in a way that mimics the dietary effects of world travel. Read More

Developing a better flu vaccine

Johns Hopkins Bloomberg School of Public Health researchers say they have developed a method that could make a nasal spray flu vaccine effective for those under two and over 49 - two groups for which the vaccine is not approved. Read More

HIV testing among older adults is declining, despite CDC recommendation

Researchers led by the UCLA Fielding School of Public Health examined HIV testing trends among adults ages 50 through 64 both before and after 2006, when the Centers for Disease Control and Prevention (CDC) recommended that most doctors automatically screen all patients for HIV regardless of whe... Read More

Evolutionary war between microorganisms affecting human health, IU biologist says

BLOOMINGTON, Ind. -- Health experts have warned for years that the overuse of antibiotics is creating "superbugs" able to resist drugs treating infection. Read More

TWiM 118 Letters

Chris writes:


Dear Vincent, I have a fun question for your panel about Mars
I was watching NASA talk about how Mars' atmosphere was stripped away and was wondering about Mars bugs. Here are some fun (probable) facts I learned.
When life was ... Read More

TWiV 379: A mouse divided

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Dengue protein modulates human enzyme: Fuel for replication

Dengue is a mosquito-borne tropical disease currently endemic in more than 10 countries. According to the World Health Organization, 390 million people are infected by dengue every year. Read More

Chickenpox vaccination does increase shingles cases, but mainly in young adults

Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought. Read More

Meningitis model shows infection's sci-fi-worthy creep into the brain

DURHAM, N.C. - Scientists at Duke Medicine are using transparent fish to watch in real time as Cryptococcal meningitis takes over the brain. The resulting images are worthy of a sci-fi movie teaser, but could be valuable in disrupting the real, crippling brain infection that kills more than 600,... Read More

How I Became a Microbial Supremacist...

In this third installment of my "Mu-Tube" video series about microbiology and microbiology education, I discuss how I was initially labeled a "microbial supremacist" as a joke, and then embraced the title with enthusiasm. I also show many examples of the microbiology-related art I use to encour... Read More

One in four hepatitis C patients denied initial approval for drug treatment

New Haven, Conn. -- Nearly one in four patients with chronic hepatitis C (HCV) are denied initial approval for a drug therapy that treats the most common strain of the infection, according to a Yale School of Medicine study. Read More

EL NIÑO HEAT SETS OFF WAVES OF DENGUE FEVER

New research shows that epidemics of dengue—caused by a mosquito-borne virus—across southeast Asia appear to be linked to the abnormally high temperatures brought by the El Niño weather phenomenon. Read More
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