Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.
Vincent and Glenn meet up with Ann and talk about her long and productive career in virology, from biochemistry to bacteriophage lambda to retroviruses.
The placenta is full of microbes, a new study finds, raising questions about how that ecosystem and mothers' oral health influence the risk of pre-term birth.
Even before a baby is born a microbial ecosystem takes up residence in the placenta, creating a microbiome that may help shape the new... Read More
Just in case anyone had lingering doubts about the cause of measles, the German courts have ruled in favor of the evidence indicating that measles is caused by a virus (wasn't aware that was up for debate nowadays...). This ruling also includes that a man who stated he would give 100,000 euros ... Read More
British and Finnish scientists have found a way of generating renewable propane using a bacterium widely found in the human intestine and say the finding is a step to commercial production of a fuel that could one day be an alternative to fossil fuel reserves.
"Although we have only produced ... Read More
The Twivsters discuss how reverse transcriptase encoded in the human genome might produce DNA copies of RNA viruses in infected cells.
Vincent visits the University of Georgia where he speaks with Zhen Fu and Biao He about their work on rabies virus and paramyxoviruses.
Chromobacterium violaceum is a gram negative bacterium known to produce a natural antibiotic violacein which has other additional properties as well.
Here I was testing the MIC for a range of antibiotics and found a amazing result wherein i could clearly see "persisters" which will at a later s... Read More
Microbes can tailor transcriptional responses to diverse environmental challenges despite having streamlined genomes and a limited number of regulators. We present data‐driven models that capture the dynamic interplay of the environment and genome‐encoded regulatory programs of two types of prok... Read More
I have been following TWIP for several years. I am a software engineer and parasitology is only an avocation. As an undergraduate in the early 80's I discovered my love of history of science and ecology, although I continued the p... Read More
Vinny and the capsids answer listener questions about the definition of life, state vaccination laws, the basic science funding problem, viral ecology, inactivation of viruses by pressure, and much more.
Hosts: Read More
Vincent meets up with Janet Butel and Rick Lloyd at Baylor College of Medicine to talk about their work on polyomaviruses and virus induced stress.
Host: Vincent Racaniello
Guests... Read More
The TWiV gang answers follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of disseminated multiple myeloma with oncolytic measles virus.
A new study will explore whether living with a dog encourages the growth of positive microorganisms in the human gut—enough to improve physical and mental health in older adults. Read More
Dear Vincent & Dickson… and Daniel,
I always enjoy listening to TWIP here in Kona, Hawaii.
Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
Scientists at the University at Buffalo are turning to an old class of antibiotics to fight new superbugs resistant to modern medicine.
A $4.4 million grant from the National Institutes of Health will allow UB researchers to develop new dosing regimens for polymyxin antibiotics.
Developed ... Read More
David writes (re lice and iron):
All I remember that I know is that one time I let my cat endure a heavy flea infestation for an unconscionably long time. I redeemed myself, if at all, by the knowledge that I slept with her a lot, and so endured a share myself (b... Read More
Like a protective tent over a colony of harmful bacteria, biofilms make the treatment of skin infections especially difficult. Microorganisms protected in a biofilm pose a significant health risk due to their antibiotic resistance and recalcitrance to treatment, and biofilm-protected bacteria ac... Read More
Researchers at Harvard and Yale have used some extreme gene-manipulation tools to engineer safety features into designer organisms.
This work goes far beyond traditional genetic engineering, which involves moving a gene from one organism to another. In this case, they're actually rewriting th... Read More