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Novel vaccine approach to human cytomegalovirus found effective

An experimental vaccine against human cytomegalovirus (CMV) infection, which endangers the developing fetus, organ transplant recipients, patients with HIV and others who have a weakened immune system, proved safe and more effective than previous vaccines developed to prevent infection by the ub... Read More

Family Tree Of Pertussis Traced, Could Lead To Better Vaccine

Whooping cough was once one of the leading killers of babies around the world. Now that it's largely controlled with a vaccine, scientists have had a chance to figure out how the disease came into being in the first place. That story is told in a study published online this week in the journal m... Read More

Mollusk parasite culturing methods drive research

Researchers at Bigelow Laboratory for Ocean Sciences dug into the last 70 years of peer-reviewed publications about protozoan parasites that infest bivalve mollusks and found that when an organism can be cultured in the laboratory, more papers and greater understanding result. Senior Research S... Read More

WHO warns against 'post-antibiotic' era

The 'post-antibiotic' era is near, according to a report released today by the World Health Organization (WHO). The decreasing effectiveness of antibiotics and other antimicrobial agents is a global problem, and a surveillance system should be established to monitor it, the group says. There is ... Read More

Scientists Convert Bacteria from Free-living to Nitrogen Fixing

If you pull up a soybean or bean plant and shake off the dirt, you might see odd swellings or bumps, like rheumatic finger joints, on its roots. Inside the cool, soil-covered bumps are bacteria that are making nitrogen with the help of an enzyme, something chemical factories can do only with the... Read More

UNC researchers discover new target for dengue virus vaccine

Using an experimental technique new to the dengue field, the labs of Ralph Baric, PhD, and Aravinda de Silva, PhD, showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue 3 to disable it. The finding, published in the Proceedings of... Read More

Malaria’s Clinical Symptoms Fade on Repeat Infections Due to Loss of Immune Cells

Children who repeatedly become infected with malaria often experience no clinical symptoms with these subsequent infections, and a team led by UC San Francisco researchers has discovered that this might be due at least in part to a depletion of specific types of immune cells.

Working in Ugand... Read More

ICAAC 2013 - ICAAC Highlights


Members of the ICAAC Program Committee present highlights by day of the ICAAC meeting and discuss sessions of particular interest.<... Read More

Tiny Algae Responsible for Mysterious Fossil Whale Graveyard?

Ever since a highway construction crew in Chile uncovered a fossil graveyard of some 40 prehistoric whales in 2010, with skeletons dating back more than five million years, scientists have wondered why so many giant animals died in one place. This week, a team of them proposed an answer: The hug... Read More

Unknown Floor isolate #2

Partial isolate of an unknown organism on trypticase soy agar exhibiting spreading and mounding in an irregular-rhizoid form with lobate margins. The colony exhibited an opaque yellow-orange pigment with a mucoid surface. This sample was obtained from a floor swab and incubated at 37°C. Read More

Small Molecule Acts As On-Off Switch for Nature's Antibiotic Factory

Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines.

Their hope now would be to see whether it is possible to manipulate this switch to make nature's anti... Read More

Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the “seesaw effect”: Taking advantage of the back door left open?

Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More

Yes! We have no bananas? It could actually happen

Banana lovers take note: The world's supply of the fruit is under attack from a fungus strain that could wipe out the popular variety that Americans eat. "It's a very serious situation," said Randy Ploetz, a professor of plant pathology at the University of Florida who in 1989 originally discove... Read More

Research identifies how bacteria produce hydrogen

Making hydrogen easily and cheaply is a dream goal for clean, sustainable energy. Bacteria have been doing exactly that for billions of years, and now chemists at the University of California, Davis, and Stanford University are revealing how they do it, and perhaps opening ways to imitate them.
... Read More

Synthesis produces new antibiotic

A fortuitous collaboration at Rice University has led to the total synthesis of a recently discovered natural antibiotic.

The laboratory recreation of a fungus-derived antibiotic, viridicatumtoxin B, may someday help bolster the fight against bacteria that evolve resistance to treatments in h... Read More

Microbes Defy Rules of DNA Code

The instructions encoded into DNA are thought to follow a universal set of rules across all domains of life. But researchers report in the May 23 issue of Science that organisms routinely break these rules.

The finding has implications for the design of synthetic life: by designing organisms ... Read More

On Teaching

A graduate student came to my office recently to say that she was increasingly bothered by anxiety and the ‘terror’ of having to speak at laboratory meetings. She had also learned a month ago that she was expected to lecture to a class organized by her mentor. The thought of having to lecture to... Read More

UTHealth researchers find up to 3,000 times the bacterial growth on hollow-head toothbrushes

Solid-head power toothbrushes retain less bacteria compared to hollow-head toothbrushes, according to researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Dentistry.

The results of the study are published in the August issue of the Journal of Dental Hyg... Read More

Gut Bacteria Lose their Tails to Evade Antibodies

New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.

In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More

Herpes infected humans before they were human

Researchers have identified the evolutionary origins of human herpes simplex virus (HSV) -1 and -2, reporting that the former infected hominids before their evolutionary split from chimpanzees 6 million years ago while the latter jumped from ancient chimpanzees to ancestors of modern humans -- H... Read More

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