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Synthesis produces new antibiotic

A fortuitous collaboration at Rice University has led to the total synthesis of a recently discovered natural antibiotic.

The laboratory recreation of a fungus-derived antibiotic, viridicatumtoxin B, may someday help bolster the fight against bacteria that evolve resistance to treatments in h... Read More

The role of uncertainty in infectious disease modelling

The study found that many models provided only cursory reference to the uncertainties of the information and data, or the parameters used

Research by scientists at the University of Liverpool has found that greater consideration of the limitations and uncertainties in infectious disease model... Read More

Who's Protecting Whom From Deadly Toxin?

Questions are swirling around a science journal's decision last year to publish a description of a newly discovered botulinum toxin while omitting key genetic details that researchers would normally disclose. The unusual case highlights important unresolved issues in how to balance scientific op... Read More

Home is where the microbes are: Home Microbiome Project announces results of study on household microbes

A person’s home is their castle, and they populate it with their own subjects: millions and millions of bacteria.

A study published tomorrow in Science provides a detailed analysis of the microbes that live in houses and apartments. The study was conducted by researchers from the U.S. Departm... Read More

Good C-DIFF Agents May Keep Our Homeland Safe

Rogue agents always add a thrilling plot twist in any spy television show, movie or Tom Clancy novel. The devastating impact these evildoers have on the world increases suspense and concern for the characters -- and bystanders -- who may become victims. Inevitably, it is up to those who strive f... Read More

Vibrio cholerae serotype O1 biotype ogawa isolated on TCBS agar in Sukraraj Tropical and Infectious Hospital , Kathmandu , Nepal .

Vibrio cholerae was isolated in the capital city Kathmandu , where as it causes cholerae endemic in certain remote parts in the country every year . Vibrio cholerae O1 ogawa serotype was isolated and identified after growth in TCBS agar and subcultured on HIA plate and performed oxidase test (+... Read More

Saudi Arabia reports 1 more death from new virus

Saudi Arabia says one more person has died from a new respiratory virus related to SARS, bringing to 55 the number of deaths in the kingdom at the center of the outbreak.

The Health Ministry said Sunday that the 37-year-old man died in Riyadh. He was among 130 people who have been infected wi... Read More

Demonstration of screening of Organic Acid producing Fungi.

Fungal Love......
Demonstration of screening of Organic Acid producing Fungi. Read More

Oral Bacteria and Cancer

Over a number of years, epidemiological studies established several well-defined risk factors for cancer, including age, heredity, diet, tobacco use, chronic viral infections, and inflammation. Paradoxically, the success of these studies left little room for incorporation of any new factors or c... Read More

This Tiny Sensor Spots Salmonella In Minutes, Not Days

A new biosensor quickly detects salmonella in food and can be easily customized to detect other types of bacteria—or even different strains for the same bacterium.

The process appears to easily outperform tests that are now standard in the food industry, according to researchers at Rice Unive... Read More

Cilia use different motors for different tasks

Cilia — short, hair-like fibers — are widely present in nature. Single-celled paramecia use one set of cilia for locomotion and another set to sweep nutrients into their oral grooves. Researchers at Brown have discovered that those two cilia sets operate at different speeds when the viscosity of... Read More

Wolbachia Genome Reduction, Phage WO, and Reproductive Parasitism

Abstract:

Wolbachia are maternally transmitted endosymbionts that often alter their arthropod hosts’ biology to favor the success of infected females, and they may also serve as a speciation microbe driving reproductive isolation. Two of these host manipulations include killing males outrigh... Read More

Parallel ERV-mediated evolution of blue egg color in chickens

The delightful word 'oocyan' refers to the trait of blue-green eggshell color that occurs in native chickens of Chile (Mapuche fowl) and some of their descendants in North America and Europe, as well as certain Asian chicken breeds (e.g. Dongxiang, Lushi).

Oocyan is an autosomal dominant trai... Read More

Calcium makes for an environmentally friendly pickle

George Washington had a collection of 476 kinds of pickles. To prevent scurvy, Christopher Columbus stocked pickles on the Niña, Pinta, and Santa Maria. Julius Caesar, believing pickles to be invigorating, added them to the Roman legions' diet. In 5000 BCE, the Babylonians were known for picklin... Read More

Predictive model a step toward using bacteria as a renewable fuel source

A new transcriptomics-based model accurately predicts how much isoprene the bacterium Bacillus subtilis will produce when stressed or nourished. This model marks a step toward understanding how changes in the bacteria's environment affect gene expression and, in turn, isoprene production. Isopre... Read More

'Transformer' protein provides new insights into Ebola virus disease

A new study reveals that a protein of the Ebola virus can transform into three distinct shapes, each with a separate function that is critical to the virus's survival. Each shape offers a potential target for developing drugs against Ebola virus disease, a hemorrhagic fever that kills up to 9 ou... Read More

Scientists develop world’s first light-activated antimicrobial surface that also works in the dark

Researchers at UCL have developed a new antibacterial material which has potential for cutting hospital acquired infections. The combination of two simple dyes with nanoscopic particles of gold is deadly to bacteria when activated by light - even under modest indoor lighting. And in a first for ... Read More

Bird flu experiments pose risk of accidental release

Research in mammals that aims to prevent future influenza pandemics raises ethical, public health concerns. Experiments creating dangerous flu strains that are transmissible between mammals pose too great a risk to human life from potential release, according to an editorial by researchers from... Read More

Key Mechanism Behind Herpes Revealed

Researchers at Lund University in Sweden have for the first time managed to measure the internal pressure that enables the herpes virus to infect cells in the human body. The discovery paves the way for the development of new medicines to combat viral infections. The results indicate good chance... Read More

New 'gut bacteria' clinical study could help reduce side-effects of radiotherapy

Researchers will examine the role of gut bacteria in influencing the side-effects patients experience after radiotherapy, in the first clinical study of its type.

The study will be carried out by researchers at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Tru... Read More

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