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Ebola Outbreak 2014 2015 by Dr. Fauci

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Prion trials and tribulations: Finding the right tools and experimental models

Prions are fascinating, enigmatic, and might teach us not only about rare prion diseases like Creutzfeld-Jakob disease, mad cow disease, or scrapie, but also about other more common neurodgenerative diseases. Two studies published on July 2nd in PLOS Pathogens report progress with novel tools an... Read More

Discovery points to a new path toward a universal flu vaccine

Flu vaccines can be something of a shot in the dark. Not only must they be given yearly, there's no guarantee the strains against which they protect will be the ones circulating once the season arrives. Read More

Early HIV treatment improves survival in some patients with newly diagnosed TB

PITTSBURGH, July 9, 2015 - Starting anti-HIV treatment within two weeks of the diagnosis of tuberculosis, or TB, improved survival among patients with both infections who had very low immune-cell counts, according to an analysis by researchers at the University of Pittsburgh Graduate School of H... Read More

Genetic differences may help explain inconsistent effectiveness of anti-HIV drug

Research with human tissue and cells suggests that genetic variations, in addition to failure to comply with treatment regimens, may account for some failures of an anti-HIV drug to treat and prevent HIV infection. Read More

BacterioFiles 221 - Co-culture Close Contact, Cats, and Cockerels

This episode: More distantly related bacteria can help each other grow (and produce lots of hydrogen) by temporarily fusing with each other!


(12.7 MB, 13.9 minutes)


Show notes: 
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TWiV 345: How a vaccine got the nod

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

Killer in a Capsule

Cryptococcus cells seen with India Ink staining from CSF of an HIV patient in Tanzania. Taken using nothing more than a smartphone camera. The negatively stained capsule is clearly visible, proving that with very simple techniques and a cellphone you can get very clear images of microorganisms Read More

Scripps research-designed drug candidate significantly reduces HIV reactivation rate

HIV-infected patients remain on antiretroviral therapy for life because the virus survives over the long-term in infected dormant cells. Interruption of current types of antiretroviral therapy results in a rebound of the virus and clinical progression to AIDS. Read More

Towards an HIV vaccine

Neutralizing antibodies (Nabs) are immune proteins that recognize, bind to, and trigger the elimination of virus before it can establish a chronic infection. How to elicit a potent Nab response capable of protecting against different HIV subtypes and against different modes of infection is criti... Read More

Researchers identify cause of heart damage in sepsis patients

Researchers at the University of Liverpool's Institute of Infection and Global Health (IGH) have discovered a common cause of heart damage in patients with sepsis.

Sepsis is the most common cause of death in hospitalised critically ill people and affects up to 18 million people world-wide ann... Read More

Newton Fund grant to aid researchers in tackling infectious disease in Malaysia

A group of collaborators led by the University of Southampton have been awarded a British Council Newton Fund Institutional Links Grant to support ground-breaking research towards reducing the burden of infectious disease in Malaysia. Read More

TWiM #107: The battle in your bladder

Vincent and Michael discuss the highly diverse microbiome of uncontacted Amerindians, and how the composition of human urine plays a role in the bat... Read More

TWiM 107 Letters

Jim writes:


Hi Vince,
For your interest in listening to physics, there is a podcast called The Titanium Physicists Podcast. They use a conversational format similar to what you use. They have a panel of experts and a guest who is not a physicist but who is accom... Read More

Devil in details

Saburo, secret ingredient, room temperature , 3 days Read More

Greenish green

Saburo,secret ingredient,room temperature , 4 days Read More

Funky mix

Saburo,secret ingredient, 3 days, room temperature . Bacteria and fungi from shoes. Read More

The sting in dengue's tail

In a new Science study, Duke-NUS Graduate Medical School Singapore (Duke-NUS) scientists have identified how small changes in dengue's viral genome can affect the virus' ability to manipulate human immune defences and spread more efficiently. This research is the first of its kind that examined ... Read More

Researchers develop world's most sensitive test to detect infectious disease, superbugs

Infectious diseases such as hepatitis C and some of the world's deadliest superbugs--C. difficile and MRSA among them--could soon be detected much earlier by a unique diagnostic test, designed to easily and quickly identify dangerous pathogens. Read More

Felinine Plays a Role in the Chasing and Fighting between Cats and Mice

A recent study found that mice may be controlled to be brave in the fight with their biggest enemy cats after smelling a chemical emitted by them and existed in their urine. Read More

The next anti-tuberculosis drug may already be in your local pharmacy

Testing thousands of approved drugs, EPFL scientists have identified an unlikely anti-tuberculosis drug: the over-the-counter antacid lansoprazole (Prevacid®). Read More
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