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Ebola Virus explained

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Insight into pathogenic fungus

The fungal pathogen Candida albicans causes yeast infections, diaper rashes and oral thrush, and is the most common fungal pathogen to infect humans. Researchers have identified a protein that the fungus uses to defend itself against the human body. Another concern with the fungus is that it can... Read More

BDP FL maleimide - BODIPY analog - fluorescent labeling of proteins

BDP FL maleimide
http://www.lumiprobe.com/p/bodipy-fl-maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More

Nutrient-absorbing surface’s assembly revealed: study

Vanderbilt University researchers have now discovered how intestinal cells build this specialized structure, which is critical for absorbing nutrients and defending against pathogens. The findings, published April 10 in the journal Cell, reveal a role for adhesion molecules in brush border assem... Read More

ICAAC 2012 - Emergence of Animal-Origin H3N2 Influenza

Public health officials will provide the latest update on the H3N2, the new strain of influenza that appears to have jumped from swine to humans and has already infected nearly 300 pe... Read More

TWiP 73 letters

Robin writes:


Liquids


Liquids are capable of forming a gas-liquid interface: maintenance of the surface requires adequate pressure in the gas. Adequate in this instance means a gas pressure greater than the vaporisation pressure in the liquid. The gas pressure... Read More

Microgravity research helping to understand the fungi within

(Phys.org) —You may not recognize it by name, but if you have ever had a child with a diaper rash, that child was likely a host to Candida albicans (C. albicans). This unwelcome "guest" can be hard to control, as it can potentially lead to serious illness in humans with weakened immune systems. ... Read More

Superbugs should scare you more than Ebola in US

The first case of Ebola in the United States was announced today, with a patient in Dallas who traveled to the US from Liberia. The resultant hysteria and xenophobia prompts this reminder. There is NO need to panic.

Ebola is NOT transmitted before a patient develops symptoms. Ebola is transmi... Read More

Antibiotic Susceptibility Test (AST) Disc in Blood sample

I am sunil pandey from kathmandu Nepal, studying B.Sc in medical microbiology at nobel college. this is AST disc in MHA from blood sample, shows the clear zone of inhibition(Kirby -Bauer disc diffusion Method). I have done this experiment as part of my study "susceptibility of antibiotics in ba... Read More

Adhering To The 'Replicon Model' The Sloppy Way

Sixty years ago Jacob, Brenner and Cuzin devised their 'Replicon Model', inspiring and useful guideline for replication research ever since. According to the model, a 'Replicon' is a genetic element replicated from a single 'Replicator'—replication origin, in modern terms—and replication is trig... Read More

Brewing yeasts reveal secrets of chromosomal warfare and dysfunction

Using two yeasts that have been used to brew tea and beer for centuries, researchers at Fred Hutchinson Cancer Research Center have revealed how reproductive barriers might rapidly arise to create species boundaries. Schizosaccharomyces pombe has been used to brew beer in Africa, whereas its clo... Read More

The bug that lost a few genes to become Black Death

About 6,000 years ago, a bacterium underwent a few genetic changes. These allowed it to expand its habitat from the guts of mice to that of fleas. Such changes happen all the time, but in this particular instance the transformation eventually resulted in the Black Death that wiped out a third of... Read More

Light-Induced Delivery of Nitric Oxide Eradicates Drug-Resistant Bacteria

Researchers at UC Santa Cruz have developed a novel approach for eradicating drug-resistant bacteria from wounds and skin infections, using light to trigger the controlled release of nitric oxide. The UCSC team developed a photoactive compound that releases nitric oxide when exposed to light, an... Read More

‘Wormy’ Pills Might Fend Off Autoimmune Diseases

Scientists have identified peptides from parasitic hookworms that can calm the body’s immune response and perhaps pave the way to treat autoimmune diseases.

Experts believe the peptide molecules could help explain why worm infections can effectively treat diseases such as multiple sclerosis, ... Read More

Ebola Virus Particles

Colorized scanning electron micrograph of filamentous Ebola virus particles (green) attached to and budding from a chronically infected VERO E6 cell (blue) (25,000x magnification).

Credit: National Institute of Allergy and Infectious Diseases (NIAID) Read More

Facilitation of horizontal transfer of antimicrobial resistance by transformation of antibiotic-induced cell-wall-deficient bacteria

It is universally accepted that the use of antibiotics will lead to antimicrobial resistance. Traditionally, the explanation to this phenomenon was random mutation and horizontal gene transfer and amplification by selective pressure. Subsequently, a second mechanism of antibiotic-induced antimic... Read More

From the archives: life at 90°C

Prokaryotes are by far the most successful superkingdom in terms of both biochemical diversity and the variety of environments conquered. Bacteria can be found living in all kinds of adverse conditions; from high alkaline lakes, to below freezing temperature, to hot volcanic vents which in some ... Read More

Six to Tango

One genome at a time can be exciting, but two even more so. I’m not entirely sure why this is, although it may explain our fascination with sex. And what if more than two entities were involved? What if the intimacy were not just between two individual organisms, but between a greater number of ... Read More

My Global Video Challenge by Dr Charles J ELIKWU, Babcock University Teaching Hospital, Nigeria

This is in celebration of the Global Handwashing Day, 2013. To God be Glory
Theme: The Power is Your Hand
Organized by the Infection Control Committee, Babcock University Teaching Hospital, Ilishan Remo, Ogun State, Nigeria Read More

Amphibian communities collapse in wake of viral outbreak

Two closely related viruses that have been introduced to northern Spain in recent years have already led to the collapse of three different species of amphibian -- the common midwife toad, the common toad, and the alpine newt -- in the protected area of Picos de Europa National Park. In all, six... Read More

ICAAC 2012 - Antibody Therapies for C. difficile

Clostridium difficile infection is an important cause of intestinal disease, primarily affecting hospitalized patients exposed to antibiotics. Infection has been associated with prolo... Read More

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