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RNA virus packaging specificity explained?

In 1969 David Baltimore proposed that poliovirus RNA replication is coupled with packaging, in that only those genomes actively replicating will be selectively encapsidated. From an evolutionary standpoint, it is an ingenious requirement to ensure that only virus genomes capable of replication ... Read More

Microbes Capable of Surviving Harsh, Mars-Like Conditions Discovered

Soil samples obtained from South American volcanoes have revealed a smattering of different microbe types that have somehow managed to survive in extreme conditions, the University of Colorado-Boulder (CU-Boulder) announced in a June 8 press release.

According to the university, the scientist... Read More

Synthetic Stool a Prospective Treatment for C. Difficile

A synthetic mixture of intestinal bacteria could one day replace stool transplants as a treatment for Clostridium difficile (C. difficile). C . difficile is a toxin-producing bacteria that can overpopulate the colon when antibiotics eradicate other, naturally protective bacteria living there.

... Read More

Researchers Create Living ‘Neon Signs’ Composed of Millions of Glowing Bacteria

In an example of life imitating art, biologists and bioengineers at UC San Diego have created a living neon sign composed of millions of bacterial cells that periodically fluoresce in unison like blinking light bulbs.

Their achievement, detailed in this week’s advance online issue of the jour... Read More

TWiV 167: It starts with a cough



Hosts: Vincent Racaniello, Dickson Despommier Read More

Common bacteria may cause colic

A bacteria that is known to be associated with more than 80% of gastric and doudenal ulcers, may be associated with infant colic. The bacteria, Helicobacter Pylori (H.pylori), is found in the lining of the of the stomach wall.

Dr. Abdelrazak Mansour Ali from Al-Azhar University in Cairo, Egyp... Read More

TWiM 25 Letters

Peter writes:


Dear TWiM team I saw this fascinating paper on how the variety of bacteria populating human skin can influence who mosquitoes chose for the... Read More

Controversial H5N1 research papers OK to publish, says U.S biosecurity panel

Two controversial papers on bird flu will be published by scientific journals this year after the go-ahead was given by a U.S biosecurity panel.

The National Science Advisory Board for Biosecurity (NSABB) took a stand over the papers last year out of concerns that details of the studies - whi... Read More

India polio-free for one year

A year has passed since the last reported case of poliomyelitis in India, which occurred on 13 January 2011 in a two year old girl in Howrah, West Bengal. Read More

Finding One Bug

A new, nanometer-sized biosensor can detect a single deadly bacterium in tainted ground beef. How? Researchers attached nanoparticles, each packed with thousands of dye molecules, to an antibody that recognizes the microbe E. coli O157:H7. When the nanoball-antibody combo comes into contact with... Read More

TWiV 188 Letters

Judi writes:


To our TWIV leaders!


If you have a mac with Apps, please go to the app store and download cell images.... I think you'll have a great time going through them.


One other thing - I listened to your show on science reform with interest but I ... Read More

New study maps hotspots of human-animal infectious diseases and emerging disease outbreaks

A new global study mapping human-animal diseases like tuberculosis (TB) and Rift Valley fever finds that an "unlucky" 13 zoonoses are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year. The vast majority occur in low- and middle-income countries.

The report, wh... Read More

E. coli: can subtractive reverse vaccinology help design a vaccine?

Escherichia coli is no stranger to the human body. In around 20% of us, E. coli is the predominant species in our gastrointestinal tract, where it lives as a commensal. But when E. coli gets out of hand it can cause anything from gastroenteritis to sepsis to urinary tract infections. It's those ... Read More

TWiP 33 Letters

Howie writes:



Twivers,


Great podcast!!!


A while ago, Dick made a comment along the lines that Sir... Read More

Jekyll and Hyde bacteria aids or kills, depending on chance

Living in the guts of worms are seemingly innocuous bacteria that contribute to their survival. With a flip of a switch, however, these same bacteria transform from harmless microbes into deadly insecticides.

In the current issue of Science, Michigan State University researchers led a study t... Read More

Microbes found thriving in Mars-like conditions

The discovery of microbes in any icy lava tube in Oregon raises hope that similar microorganisms could survive in the very similar conditions to be found on Mars.

The microbes are coping with near-freezing temperatures and low levels of oxygen, and can even grow in the absence of organic food... Read More

Eternal Yogurt: The Starter That Lives Forever

If you make your own yogurt, there's a chance your yogurt could outlive you.
That's because some bacteria that grow and feed on the sugar in milk – the process that ferments milk into yogurt — can procreate indefinitely in new generations of yogurt.

But not all yogurts have these immortal po... Read More

Policy On High-Risk Biological Research Tightened

The Obama administration has announced a new policy to handle the risks posed by legitimate biological research that could, in the wrong hands, threaten the public.

The move comes in response to a huge debate over recent experiments on bird flu virus that got funding from the National Institu... Read More

In proteins, a possible antibiotic revolution

The problem with antibiotics? We’re running out of them.

Over the last half-decade, our arsenal of powerful bacteria-killing medicines has slowly (though in biological time, rapidly) been depleted as nature, through evolution, outwits our efforts to develop chemical tools that can save us fro... Read More

A confocal micrograph of an intestinal biopsy from a child infected with shiga toxin-producing E. coli.

Shiga toxin is an extremely potent toxin that is produced when the bacterium contains a bacteriophage carrying the toxin gene. It is closely linked with Haemolytic Uraemic Syndrome and acute renal failure in children. After ingestion via contaminated food or water the E. coli bacteria colonize t... Read More

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