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Small Comfort: Nanomedicine Able to Penetrate Bodily Defenses

Researchers use stealthy nanoscale particles to infiltrate vaginal mucus and keep herpes at bay in mice.

Tears and a runny nose can be unpleasant on a windy day, but these mucosal secretions play a vital role in protecting the body from viruses and other malicious microbes. Unfortunately, muc... Read More

Air pollution and tuberculosis may be connected

In a new study, scientists have determined a possible link between exposure to a common component of urban air pollution and a change in the function of important immune cells that protect against the bacteria that cause tuberculosis.

In their finding, a team of researchers, led by Dr. Steph... Read More

The Microbial Academy of Sciences: What Bacteria Can Discover That We Can’t

Other than basic stuff like the Earth rotating around the sun and E=MC2, how much do you know about the universe? Most people would say: not very much. But if you’re a theoretical physicist, you probably know quite a bit more--but still not that much; most of the mysteries of the universe still ... Read More

A mad cow in America

A dairy cow in California is the fourth known American case of mad cow disease, which is caused by prions, infectious agents composed only of protein (the story hit the press the day after my lecture on this type of illness). Unlike viruses, prions have no nucleic acid and no protective coat. Bu... Read More

Fermented Fashion via @wabibitotweets @phylogenomics

The Micro'be' project by contemporary textile artist and lecturer Donna Franklin, and scientist Gary Cass, explores fashion and technology's newest frontier: garments made from the bacterial fermentation of wine and beer.

The project's eureka moment came about through a vat of Australian red... Read More

Computer-Designed Proteins Programmed to Disarm Variety of Flu Viruses

Computer-designed proteins are under construction to fight the flu. Researchers are demonstrating that proteins found in nature, but that do not normally bind the flu, can be engineered to act as broad-spectrum antiviral agents against a variety of flu virus strains, including H1N1 pandemic infl... Read More

Copy of the genetic makeup travels in a protein suitcase

Scientists from the Institute for Physical and Theoretical Chemistry at the University of Bonn have succeeded for the first time in the real time filming of the transport of an important information carrier in biological cells that is practically unmodified. This paper has now been published in ... Read More

Intestinal artillery launches anti-bacterial attack

The epithelial cells that line the intestines fire bacteria-fighting “bullets” into the gut, Vanderbilt University researchers have discovered.

The findings, featured on the cover of the April 10 issue of Current Biology, represent a new mechanism for defending the body against gut microbes.
... Read More

Titan's tides reveal hidden ocean that could host life

Alien hunters take note: a global water ocean potentially bigger than all those on Earth combined, is sloshing beneath Titan's icy crust.

Combined with the cocktail of organic chemicals already known to exist on Titan, abundant water could make the moon prime real estate for life – though mor... Read More

Study upholds immune system’s role in autism

Changes in an overactive immune system can contribute to autism-like behaviors in mice, new research shows.

Scientists at the California Institute of Technology (Caltech) pioneered the study of the link between irregularities in the immune system and neurodevelopmental disorders such as auti... Read More

Asking old human tissue to answer new scientific questions

Pirates used to say that “dead men tell no tales.” Of course, the buccaneers had never heard of the polymerase chain reaction. Dead men turn out to be loaded with information if you can get your hands on them — or better yet, on small preserved pieces.

The genomics revolution, two decades old... Read More

Meningitis Vaccine Being Developed From Common Cold Virus

A leading cause for meningitis and septicemia in the UK is meningococcus B (MenB) bacterium infection. Healthy children can become severely ill within just a few hours if they contract meningitis or septicemia, as both illnesses develop randomly and with alarming speed. It often occurs in babies... Read More

The Extra Pounds You Can't Afford to Lose: An Interview With Microbiologist Margaret McFall-Ngai

Recent revelations about our microscopic partners and tenants are numerically startling, if not downright existential. Try these for starters: Most of the cells within your body are not human cells, and you are literally teeming with pounds of busy microbes, working to earn their keep while you ... Read More

Grow Your Own Computer?

There may be a new wave of computer technology on the way thanks to scientists at the University of Leeds and Japan’s University of Agriculture and Technology: Growing your own computer.

Magnet-making bacteria may be used to create the next generation of hard drives, making them much smaller ... Read More

Some Like It Very Hot

Russian scientists have now poured 60 tonnes of freon and kerosene down the four-kilometre bore hole that plunges through the ice above Lake Vostok in Antarctica. This will stop the hole freezing up during the long Antarctic winter. When summer comes, the Russian team will return to drill the la... Read More

TWiV 173 Letters

Judi writes:


A listener pick - since I know you all really enjoy the visualization of science!


http:... Read More

How medicine created a bacteria problem

On a warm afternoon in summer we were sitting in the lecture theatre, learning about germs. A microbiologist was showing us slides of enormously magnified bacteria (“God, this is like bug Imax!” said the girl behind me). The lecturer had a cold; he was coughing dramatically. After a prolonged bo... Read More

Built-in dengue virus killer found in humans

Scientists may have hit gold in their fight against dengue. They have located a human antibody that can neutralise and kill its virus within two hours.

Significantly, they have also identified a way to reproduce this antibody in large quantities, potentially opening the door to a cure for den... Read More

Aaron J. Shatkin, 77

Aaron J. Shatkin was well known for his work on reoviruses beginning in the 1960s in his laboratory at the Roche Institute of Molecular Biology in Nutley, NJ and then at Rutgers University. He was among the first to appreciate that virus particles contained many different enzymes, such as RNA po... Read More

Slow-Motion Microbes Still Living off Dino-era "Lunch Box"

Buried under the seafloor for 86 million years, a bacterial community lives so slowly it's still surviving on a "lunch box" from dinosaur days, a new study says. (See marine-microbe pictures.)

It's been known since the 1990s that microbes can live trapped in ocean sediments for millions of ye... Read More

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