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TWiP 40: Doctor, there's a worm in my eye!

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Hosts: Vincent Racaniello and Dickson Despommier


Vincent and Dickson discuss l... Read More

TWiP 41: Flying and crawling beasts

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Hosts: Vincent Racaniello and Dickson Despommier


Vincent and Dickson... Read More

TWiM #31: Screen door on a submarine

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Hosts: Vincent Racaniello, Jo Handelsman Read More

BacterioFiles Micro Edition 87 - Fermenter Fixes Folate Faults

This episode: Probiotics could help prevent folate deficiency!



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TWiV 190: The second ferret of the Apocalypse

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Hosts: Vincent Racaniello, Alan Dove, and Read More

TWiV 192: Viral tertulia

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Hosts: Vincent Racaniello, Alan Dove, and  Read More

TWiM 34 Letters

Peter writes:

Dear TWiM Team


I see that some action is now being taken in America against the non-therapeutic use of antibiotics as livestock growth promoters:


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The Black Queen Hypothesis: how microbes lose a necessary function and survive to tell the tale

Pared down genomes are the norm in symbiotic microbes, but how do non-symbionts get away with cutting out functions it would appear that they need? The authors of an Opinion piece in mBio this week explain their ideas about the matter. They say microbes that shed necessary functions may well be ... Read More

Millions of germs fly when you enter the room

A person’s mere presence in a room can add 37 million bacteria to the air every hour, a new study finds.

The bacterial material is largely left behind by previous occupants and stirred up from the floor when someone enters.

“We live in this microbial soup, and a big ingredient is our own m... Read More

TWiV 172: Two can be as bad as one

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Hosts: Vincent Racaniello and Kathy Spindler


<... Read More

Human Microbiome Journal Club: The Pros of Probiotics

We’ve all heard the claims of probiotic yogurts and their benefits for human health, but aside from improving our belly dancing skills, what exactly are probiotic bacteria doing?

An elegant study from the Jeffrey Gordon lab explored the effects of consuming fermented milk products (FMPs) cont... Read More

Food borne bacteria sickens 8 in Illinois, 93 nationwide

Food safety officials are investigating whether raw fish in sushi and other foods is responsible for a multi-state Salmonella outbreak that has sickened eight people in Illinois.

So far, no deaths have been connected to the strain of the bacteria, which has sent 10 people to the hospital and ... Read More

A viral mashup in snakes

If you know anything about snakes you might be familiar with snake inclusion body disease, or IBD. This transmissible and fatal disease affects snakes of a variety of species but has been best studied in boas. The name comes from the presence of large masses (inclusions) in the cytoplasm of cell... Read More

Microbes Go Rafting on Floating Volcanic Rocks

Volcanoes bring death and destruction, but out of the ashes life soon finds fertile ground. A unique experiment is sifting through floating debris from an ongoing volcanic event to see how microbes move in. The results may help in assessing a recent hypothesis that the first life forms may have ... Read More

New study maps hotspots of human-animal infectious diseases and emerging disease outbreaks

A new global study mapping human-animal diseases like tuberculosis (TB) and Rift Valley fever finds that an "unlucky" 13 zoonoses are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year. The vast majority occur in low- and middle-income countries.

The report, wh... Read More

A confocal micrograph of an intestinal biopsy from a child infected with shiga toxin-producing E. coli.

Shiga toxin is an extremely potent toxin that is produced when the bacterium contains a bacteriophage carrying the toxin gene. It is closely linked with Haemolytic Uraemic Syndrome and acute renal failure in children. After ingestion via contaminated food or water the E. coli bacteria colonize t... Read More

Jekyll and Hyde bacteria aids or kills, depending on chance

Living in the guts of worms are seemingly innocuous bacteria that contribute to their survival. With a flip of a switch, however, these same bacteria transform from harmless microbes into deadly insecticides.

In the current issue of Science, Michigan State University researchers led a study t... Read More

E. coli: can subtractive reverse vaccinology help design a vaccine?

Escherichia coli is no stranger to the human body. In around 20% of us, E. coli is the predominant species in our gastrointestinal tract, where it lives as a commensal. But when E. coli gets out of hand it can cause anything from gastroenteritis to sepsis to urinary tract infections. It's those ... Read More

Small Comfort: Nanomedicine Able to Penetrate Bodily Defenses

Researchers use stealthy nanoscale particles to infiltrate vaginal mucus and keep herpes at bay in mice.

Tears and a runny nose can be unpleasant on a windy day, but these mucosal secretions play a vital role in protecting the body from viruses and other malicious microbes. Unfortunately, muc... Read More

Intestinal artillery launches anti-bacterial attack

The epithelial cells that line the intestines fire bacteria-fighting “bullets” into the gut, Vanderbilt University researchers have discovered.

The findings, featured on the cover of the April 10 issue of Current Biology, represent a new mechanism for defending the body against gut microbes.
... Read More
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