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TWiM #32: Not the shadow biosphere

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Hosts: Vincent Racaniello, Read More

TWiM #33: Tuning the immune organ

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Hosts: Vincent Racaniello, Read More

TWiV Live in Dublin (MWV58)

Watch Vincent Racaniello and guests Read More

Educating the World about Microbes

Vincent Racaniello accepts the Peter Wildy Prize for Microbiology Education, awarded annually by the Society for General Microbiology for an outstanding contribution to microbiology education. Filmed at the Dublin Convention Centre in Dublin, Ireland. Read More

Engineered Gut Bacteria Reverse Type 1 Diabetes in Experimental Mice

Scientists have managed to reverse type 1 diabetes (T1D) in experimental mice by giving the animals an oral course of harmless gut bacteria that had been engineered to secrete the whole proinsulin autoantigen (PINS) and the immunomodulatory human cytokine IL-10 (hIL10). An international team led... Read More

One Health: Humans, Animals and the Environment

The health of humans, animals, and the environment are inextricably interconnected. Disruption of the environment often creates new niches for the evolution of infectious diseases, and provides opportunities for the transmission of pathogens to animals or humans. The majority of infectious disea... Read More

TWiV 176: Ave magi, virorum!

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Hosts: Vincent RacanielloAlan Dove, and Rich Condit


Vincent,... Read More

The Latest News from the Human Microbiome Project

The NIH Human Microbiome Project has been a 5-year endeavor to produce community resources to support the field of human microbiome research. Although the HMP has already produced hundreds of peer-reviewed publications, in the past week 2 major HMP Consortium papers as well as 20+ companion pap... Read More

TWiV 187 Letters

Don writes:


thank you all for sharing your knowledge in such a comprehensible manner. Thank you also for your stand against bureaucratic censorship in the H5N1 research, and your win. I have two questions. Is H5N1 a highly specific test for a human ge... Read More

TWiV 194: Five postdocs in North America

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Hosts: Vincent Racaniello, Matthew Daugherty, Jondavid d... Read More

TWiV 173: Going to bat for flu research

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Hosts: Vincent RacanielloAlan Dove Read More

TWiM 34 Letters

Peter writes:

Dear TWiM Team


I see that some action is now being taken in America against the non-therapeutic use of antibiotics as livestock growth promoters:


Read More

48% of Retail Chicken Contaminated with E. Coli

A recent test of packaged raw chicken products bought at grocery stores across the country found that roughly half of them were contaminated with the bacteria E. coli.

E. coli, which the study said was an indicator of fecal contamination, was found in 48 percent of 120 chicken products bought... Read More

A spike for piercing the cell membrane

Some viruses that infect bacteria (bacteriophages) deliver their DNA into the host cell with an amazing injection machine. The tailed bacteriophages (such as T4, illustrated) store their DNA in a capsid attached to a long tail tube that is surrounded by a sheath. At the bottom of the tube is a b... Read More

Harmful Bacteria Can Be Curbed With Copper

Salmonella enterica is a leading cause of diarrhea illness worldwide, according to Sadhana Ravishankar, an assistant professor in the University of Arizona department of veterinary science and microbiology.

Each year the tiny, rod-shaped species of bacteria with a love for rapid reproduction ... Read More

Serratia marcescens on a DNA plate

Serratia marcescens streaked on a DNA plate and incubated for 48 hours at room temperature. Read More

E. coli: can subtractive reverse vaccinology help design a vaccine?

Escherichia coli is no stranger to the human body. In around 20% of us, E. coli is the predominant species in our gastrointestinal tract, where it lives as a commensal. But when E. coli gets out of hand it can cause anything from gastroenteritis to sepsis to urinary tract infections. It's those ... Read More

The Microbial Academy of Sciences: What Bacteria Can Discover That We Can’t

Other than basic stuff like the Earth rotating around the sun and E=MC2, how much do you know about the universe? Most people would say: not very much. But if you’re a theoretical physicist, you probably know quite a bit more--but still not that much; most of the mysteries of the universe still ... Read More

Computer-Designed Proteins Programmed to Disarm Variety of Flu Viruses

Computer-designed proteins are under construction to fight the flu. Researchers are demonstrating that proteins found in nature, but that do not normally bind the flu, can be engineered to act as broad-spectrum antiviral agents against a variety of flu virus strains, including H1N1 pandemic infl... Read More

Microbiologist Uses Viruses to Fight Bacteria

After a decade of research, ContraFect Corporation, a small biotech company based in Yonkers, N.Y., is preparing to test bacteriophages—viruses that infect and destroy bacteria—in people as a potential alternative to overused antibiotics for treating and preventing bacterial infections. The firs... Read More
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