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Researcher pioneers bacterial infection treatment using novel target: Vesicles

Bacterial infection takes hold in the body when a pathogenic microorganism delivers toxins to healthy cells. One way bacteria accomplish this is by releasing vesicles, which act as tiny envelopes transporting toxins and other virulence factors to host cells. These toxins allow the bacteria to "m... Read More

Moving to Zika Virus

I have worked on polio virus in my laboratory at Columbia University for 35 years. When that virus is eradicated--perhaps in the next few years--we will have to destroy all of our virus stocks. When that happens, I can either go home, or find another virus.

When Zika virus stepped into the w... Read More

Microbiologist Christmas Wreath, Unknown Organisms seem on Washed Hand Print #2,

Unknown organism seem after washing hands on a hand print grown on TSA. Larger organism (possible Bacillus spp) is circular, edges not smooth, mucoid with rhizoid like growth towards the edges. Second smaller organism is yellow, mucoid, and has something erupting from the center. Read More

The classic and current studies of bacterial endospore morphology

Recently, one of the Journal of Bacteriology Classic Spotlight series highlighted the numerous studies on bacterial spores that have been published in the journal throughout the years. Bacterial endospores, the resilient and relatively quiescent bacterial structures first identified in the 1800s... Read More

Microbiology Myths Debunked: Scientific Analysis of the Five Second Rule

While walking through your house, you drop a granola bar you were eating. Quick – do you pick it up and eat it? Is the ground too dirty to eat from? Does the amount of time the food sits on the ground matter? Will more microbes gather onto the snack as you decide whether or not to continue noshi... Read More

Study reveals how herpes virus tricks the immune system

With over half the U.S. population infected, most people are familiar with the pesky cold sore outbreaks caused by the herpes virus. The virus outsmarts the immune system by interfering with the process that normally allows immune cells to recognize and destroy foreign invaders. How exactly the ... Read More

Targeting the gut microbiome to fight heart disease

Is the way to treat heart disease through a person's stomach? According to a new study, the answer is yes. Researchers have found that a compound found in red wine, resveratrol, reduces the risk of heart disease by changing the gut microbiome.

Cardiovascular disease remains the leading cause ... Read More

How Forest Loss Is Leading To a Rise in Human Disease

In Borneo, an island shared by Indonesia and Malaysia, some of the world’s oldest tropical forests are being cut down and replaced with oil palm plantations at a breakneck pace. Wiping forests high in biodiversity off the land for monoculture plantations causes numerous environmental problems, f... Read More

Immune system maintains a memory of past infections by priming genes for future encounters

Our ability to fight off recurrent infections, such as colds or flu, may lie in the 'immunological memory' found in a newly discovered class of gene regulatory elements, according to research from the University of Birmingham, supported by the BBSRC and Bloodwise. Read More

A cultural revolution in the study of the gut microbiome

(BOSTON) - It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst can lead to life-threatening complications. While abnormal imm... Read More

Under the weather? A blood test can tell if antibiotics are needed

DURHAM, N.C. -- Researchers at Duke Health are fine-tuning a test that can determine whether a respiratory illness is caused by infection from a virus or bacteria so that antibiotics can be more precisely prescribed. Read More

BacterioFiles 267 - Crust Color Cooks Communities

This episode: Cyanobacteria in biocrusts produce pigments that heat their surroundings up to 10 degrees hotter!


(7 MB, 7.6 minutes)


Show notes: 
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People with rage disorder twice as likely to have latent toxoplasmosis parasite infection

Individuals with a psychiatric disorder involving recurrent bouts of extreme, impulsive anger--road rage, for example--are more than twice as likely to have been exposed to a common parasite than healthy individuals with no psychiatric diagnosis. Read More

Using TALEs to turn off any gene in E. coli

UW-Madison researchers engineered TALEs to transcriptionally repress any gene in E. coli. The results, published in Nature Chemical Biology, offer a new way to fine-tune bacterial physiology. Although TALEs have long been used for gene editing or transcriptional activation, this is one of the fi... Read More

Zika virus plaque assay

Several weeks ago we perfected a plaque assay for Zika virus, based on our existing assays for enteroviruses. Shown is a photograph of two plates stained with crystal virolet with clearly delineated plaques. The cells are Vero and the Zika virus strain is MR766, an African isolate. Anyone intere... Read More

Acid-fast bacilli

Acid-fast bacilli in auramine rhodamine stain. Read More

Environmental disturbances decrease the variability of microbial populations

A central pursuit of microbial ecology is to accurately model changes in microbial community composition in response to environmental factors. This goal requires a thorough understanding of the drivers of variability in microbial populations. However, most microbial ecology studies focus on the ... Read More

Motherboard: Your Showerhead Is Crammed Full of Bacteria That Scientists Want to Study

Scientists know very little about the kinds of bacteria that we interact with on a daily basis in our homes. Researchers from Colorado, and North Carolina are interested in what kinds of microbes are living in your shower head.

They are hoping to find out where Nontuberculous mycobacteria is... Read More

Novel small-molecule antiviral compound protects monkeys from deadly Ebola virus

Rhesus monkeys were completely protected from Ebola virus when treated three days after infection with a compound that blocks the virus's ability to replicate. These encouraging preclinical results suggest the compound, known as GS-5734, should be further developed as a potential treatment, acco... Read More

UK will need to act faster when inevitable next Ebola emerges

Ad hoc, uncoordinated and late. That’s how the UK government’s response to West Africa’s Ebola outbreak has been described in a report published on Monday by the House of Commons Science and Technology Select Committee.

The report calls for changes to enable the UK to identify threats earlier... Read More
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