Researchers who have fought for years to get full data on Roche's flu medicine Tamiflu said on Thursday that governments who stockpile it are wasting billions of dollars on a drug whose effectiveness is in doubt.
In a review of trial data on Tamiflu, and on GlaxoSmithKline's flu drug Relenza,... Read More
We continue our semi-annual ritual and post this quick tour of our blog posts published since December, 2012.
Our new section dealing with “pictures that made a difference but may be nearly forgotten by now” seems to be off to a good start. Please send us suggestions of... Read More
Food transit through the small intestine affects the body's absorption of nutrients and, consequently, our health. The discovery that food transit time is regulated by a hormone indicates new ways to increase the intestinal absorption of nutrients, and thus potentially treat malnutrition.
One... Read More
Australian researchers have found that zinc can 'starve' one of the world's most deadly bacteria by preventing its uptake of an essential metal.
The finding, by infectious disease researchers at the University of Adelaide and The University of Queensland, opens the way for further work to des... Read More
Scientists have long believed that microorganisms that produce methane swim toward the hydrogen gas they need to stay alive, but it has been too hard to prove in the lab.
Montana State University researchers have now overcome those challenges, allowing them to verify it for the first time, sa... Read More
A clinical trial of an innovative vaccine is occurring. The vaccine could offer hope to patients with advanced ovarian cancer. The vaccine, which is derived from the patient's tumor cells, is designed to jumpstart the patient's immune system to attack and kill cancer cells.
Ovarian cancer is ... Read More
I offer this as an echo to Elio's post from last October, Teaching E. coli to Endocytose. There Elio reported the recent education of E. coli by the heterologous expression of a mammalian gene. I tell of a bacterium instructed by a phage.
Apparently Pseudomonas phage φ6 missed that classic 19... Read More
Actin is shown in red. From Clarke, M., and Maddera, L. (2006). Phagocyte meets prey: Uptake, internalization, and killing of bacteria by Dictyostelium amoebae. Eur. J. Cell Biol. 85:1001-1010; reproduced with permission from Elsevier. Honorable mention 2013 Bioscapes Competition. Dr. Margaret ... Read More
Researchers at Duke University say they have created a blood test that can determine whether a person's respiratory illness is caused by a bacterial infection or a virus, with over 90 percent accuracy.
What's more, the test only takes about 12 hours to get results. Current methods take severa... Read More
Famed astronomer and writer Carl Sagan said in his book Cosmos: “The nitrogen in our DNA, the calcium in our teeth, the iron in our blood, the carbon in our apple pies were made in the interiors of collapsing stars. We are made of starstuff.” And so are microbes, we must add. To understand the s... Read More
Mathematicians have found that by varying the timing of treatments, doctors may be able to increase the odds that a disease outbreak will die off suddenly.
Herding cats is a cakewalk compared with getting people to take flu vaccine shots in the last weeks of summer—work, school, limited pharm... Read More
Viruses are obligate intracellular parasites: they must enter a cell to reproduce. To gain access to the cell interior, a virus must first bind to one or more specific receptor molecules on the cell surface. Cell receptors for viruses do not exist only to serve viruses: they also have cellular f... Read More
We live in a world run by microbes, the vast majority of which we have yet to identify or name. We can only refer to them collectively as the microbial dark matter (MDM). However you define a prokaryotic species, and however you tally them once identified, there is a huge gap between the 12,000 ... Read More
Phenotypic test for detection of AmpC β-lactamases.
boronic acid is inhibitor of ampC β-lactamases. result: if zone of inhibition in Cefoxitin(FOX)+Boronic acid(BA) > Cefoxitin(FOX)=5MM.it indicates amp c producer. media :MHA organism: klebisella pneumoniae our resarch work on AmpC β-lactama... Read More
Excerpt from Science Now "Gut Microbes Can Split a Species"; see link above to read the Science article
Here's how to create a new species. Put animals—say finches—from the same species on separate islands and let them do their thing for many, many generations. Over time, each group will ada... Read More
Microbial virulence is a complex and often multifactorial phenotype, intricately linked to a pathogen’s evolutionary trajectory. Toxicity, the ability to destroy host cell membranes, and adhesion, the ability to adhere to human tissues, are the major virulence factors of many bacterial pathogens... Read More
The current hot spell of weather has seen increased activities by flies whether in the kitchen or across picnic food and barbecues.
It may make grim reading but every fly leaves a calling card in the form of bacterial deposits.
These deposits come not only from their legs, but also from th... Read More
The mosquito-borne infection is cropping up in Florida, but mysteriously not in similar regions in the nation.
Most Americans lose little sleep over dengue fever. The mosquito-borne infection is a leading killer in the tropics and subtropics, but it’s been a long-held belief that ubiquitous a... Read More
What makes a harmless virus turn lethal? For the deadliest infectious disease in cats, Cornell scientists now know.
After gathering the world’s largest sample collection for feline infectious peritonitis (FIP), they uncovered the holy grail of a 30-year quest for the mutation that turns it fa... Read More
In May 1984, readers of an article by Schwartz and Cantor in the prestigious journal Cell were to stumble upon pictures of DNA agarose gels that were among the lousiest of such ever published after the method was introduced in the early 70s. Why did the editors of Cell risk their reputation? Or ... Read More