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Molecular mechanisms of resistance

The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.

Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More

Muddled about MERS? Here’s A Quick Guide

While I was working on the “H1N-What?” post, I also knew there would soon be questions about MERS (Middle East Respiratory Syndrome), just as there were about SARS. So here are the essentials of what we know and don’t know about MERS—which has just been reported in the U.S.—as well as intriguing... Read More

Researchers Identify Protein That Helps Control Common Viral Infection

Infectious disease specialists at the Johns Hopkins Children’s Center have identified a protein that regulates the body’s immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune sys... Read More

Scientists Figure Out How Microbes Make Wine Good

Yeast aren’t the only microbes that help turn boring grapes into the delicious, seductive, complex, confusing, subtle, and totally splendiferous tonic known as wine. In addition to those well-known fermenters, a type of bacteria called Oenococcus oeni (for reasons that will be obvious to oenophi... Read More

Rare byproduct of marine bacteria kills cancer cells by snipping their DNA

Yale University researchers have determined how a scarce molecule produced by marine bacteria can kill cancer cells, paving the way for the development of new, low-dose chemotherapies.

The molecule, lomaiviticin A, was previously shown to be lethal to cultured human cancer cells, but the mech... Read More

Researchers find that going with the flow makes bacteria stick

In a surprising new finding, researchers have discovered that bacterial movement is impeded in flowing water, enhancing the likelihood that the microbes will attach to surfaces. The new work could have implications for the study of marine ecosystems, and for our understanding of how infections t... Read More

A quicker, cheaper way to detect staph in the body

Probe identifies staph bacteria without need for biopsies. Chances are you won’t know you’ve got a staph infection until the test results come in, days after the symptoms first appear. But what if your physician could identify the infection much more quickly and without having to take a biopsy a... Read More

Ebola outbreak “out of all proportion” and severity cannot be predicted

A mathematical model that replicates Ebola outbreaks can no longer be used to ascertain the eventual scale of the current epidemic, finds research conducted by the University of Warwick.

Dr Thomas House, of the University’s Warwick Mathematics Institute, developed a model that incorporated da... Read More

Insight into pathogenic fungus

The fungal pathogen Candida albicans causes yeast infections, diaper rashes and oral thrush, and is the most common fungal pathogen to infect humans. Researchers have identified a protein that the fungus uses to defend itself against the human body. Another concern with the fungus is that it can... Read More

How a plant beckons the bacteria that will do it harm

A common plant puts out a welcome mat to bacteria seeking to invade, and scientists have discovered the mat's molecular mix. The study published this week in the Proceedings of the National Academy of Sciences reveals new targets during the battle between microbe and host that researchers can ex... Read More

Scientists explore the mechanisms of viruses' shells

The genome of viruses is usually enclosed inside a shell called capsid. Capsids have unique mechanic properties: they have to be resistant and at the same time capable of dissolving in order to release the genome into the infected cell. The scientists of the International School for Advanced Stu... Read More

Research shows bacteria can combat dangerous gas leaks

Bacteria could mop up naturally-occurring and man-made leaks of natural gases before they are released into the atmosphere and cause global warming - according to new research from the University of East Anglia.

Findings published today in the journal Nature shows how a single bacterial strai... Read More

Dairy scientist targets heat-resistant microbes

Corralling desperados with names like bacillus and paenibacillus will require ingenuity and an arsenal of weapons. These outlaws aren't rustling cattle—they're making milk sour and cheese soft and crumbly.

For more than a century, milk has been heated to kill any bacteria or pathogens that ca... Read More

BDP FL maleimide - BODIPY analog - fluorescent labeling of proteins

BDP FL maleimide
http://www.lumiprobe.com/p/bodipy-fl-maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More

Microgravity research helping to understand the fungi within

(Phys.org) —You may not recognize it by name, but if you have ever had a child with a diaper rash, that child was likely a host to Candida albicans (C. albicans). This unwelcome "guest" can be hard to control, as it can potentially lead to serious illness in humans with weakened immune systems. ... Read More

Nutrient-absorbing surface’s assembly revealed: study

Vanderbilt University researchers have now discovered how intestinal cells build this specialized structure, which is critical for absorbing nutrients and defending against pathogens. The findings, published April 10 in the journal Cell, reveal a role for adhesion molecules in brush border assem... Read More

Superbugs should scare you more than Ebola in US

The first case of Ebola in the United States was announced today, with a patient in Dallas who traveled to the US from Liberia. The resultant hysteria and xenophobia prompts this reminder. There is NO need to panic.

Ebola is NOT transmitted before a patient develops symptoms. Ebola is transmi... Read More

Brewing yeasts reveal secrets of chromosomal warfare and dysfunction

Using two yeasts that have been used to brew tea and beer for centuries, researchers at Fred Hutchinson Cancer Research Center have revealed how reproductive barriers might rapidly arise to create species boundaries. Schizosaccharomyces pombe has been used to brew beer in Africa, whereas its clo... Read More

Adhering To The 'Replicon Model' The Sloppy Way

Sixty years ago Jacob, Brenner and Cuzin devised their 'Replicon Model', inspiring and useful guideline for replication research ever since. According to the model, a 'Replicon' is a genetic element replicated from a single 'Replicator'—replication origin, in modern terms—and replication is trig... Read More

‘Wormy’ Pills Might Fend Off Autoimmune Diseases

Scientists have identified peptides from parasitic hookworms that can calm the body’s immune response and perhaps pave the way to treat autoimmune diseases.

Experts believe the peptide molecules could help explain why worm infections can effectively treat diseases such as multiple sclerosis, ... Read More

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