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Pictures Considered #18. Pictures of Shigella by Shiga

The journal Zentralblatt für Bakteriologie, Parasitenkunde u. Infektionskrankheiten was one of the leading publication in the early days of Microbiology. Many of the great discoveries of microbial pathogens were published therein. An example is the 1898 Japanese microbiologist Kiyoshi Shiga acco... Read More

Microbes Swim to Hydrogen Gas

Scientists have long believed that microorganisms that produce methane swim toward the hydrogen gas they need to stay alive, but it has been too hard to prove in the lab.

Montana State University researchers have now overcome those challenges, allowing them to verify it for the first time, sa... Read More

Paper device spots antibiotic-resistant bacteria

Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas pick the most appropriate treatment for bacterial infections.

Click on 'source' to read more Read More

The typhoid fever pathogen uses a cloaking mechanism to evade neutrophil neutralization

Typhoid fever is caused by systemic infection with Salmonella enterica Typhi. In contrast, infection with the closely related bacterium Salmonella enterica Thyphimurium is usually limited to the gut and causes less serious diarrheal disease. Research comparing the two pathogens reveals how S. Ty... Read More

Vinegar kills tuberculosis and other mycobacteria (press release)

The active ingredient in vinegar, acetic acid, can effectively kill mycobacteria, even highly drug-resistant Mycobacterium tuberculosis, an international team of researchers from Venezuela, France, and the US reports in mBio®, the online open-access journal of the American Society for Microbiolo... Read More

New genomics technique could improve treatment and control of malaria

Single-cell genomics could provide new insight into the biology of malaria parasites (including their virulence and levels of drug resistance) to ultimately improve treatment and control of the disease, according to new research funded by the Wellcome Trust and the National Institutes of Health.... Read More

Osmotic pressure

A) Bacillus subtilis, (B) Staphlococcus aureus and (C) Escherichia coli were grown on BHI media with varying concentrations of NaCl (0.85%, 5%, 7.5%, 10%, and 20%) at 37 degrees C for 24 hrs. Read More

Knowing how bacteria take out trash could lead to new antibiotics

A team of scientists has reconstructed how bacteria tightly control their growth and division, the cell cycle, by destroying specific proteins through regulated protein degradation. All organisms use controlled protein degradation to alter cell behavior in response to changing environment. A pro... Read More

Pictures Considered #10. The Origin of Pulsed-Field Gel Electrophoresis

In May 1984, readers of an article by Schwartz and Cantor in the prestigious journal Cell were to stumble upon pictures of DNA agarose gels that were among the lousiest of such ever published after the method was introduced in the early 70s. Why did the editors of Cell risk their reputation? Or ... Read More

Scientists Turn Dr. Frankenstein, Re-Write Bacteria’s Entire Genome

It may sound like science fiction, but researchers at Yale and Harvard have taken the first steps towards a Dr. Frankenstein-type reality, by fundamentally changing the genetic code of an organism.

The scientists were able to rewrite the genetic alphabet of the common bacteria E.coli, creatin... Read More

Infectious diseases: Smallpox watch

In 2011, while construction workers were digging a foundation at a site in Queens, New York, their equipment struck against something metal. Then a body rolled out of the rubble. Thinking that they might have unearthed the shallow grave of a murder victim, the workers immediately called the New ... Read More

Harvard scientists control cells following transplantation, from the inside out

Harvard stem cells scientists at Brigham and Women’s Hospital and MIT can now engineer cells that are more easily controlled following transplantation, potentially making cell therapies, hundreds of which are currently in clinical trials across the United States, more functional and efficient.
... Read More

Central Park Features Worldwide Soil Microbes

"If you want to find unique diversity and if you want to find a wide range of different below-ground organisms, you don't have to travel around the world. You can walk across Central Park."

That statement comes from Noah Fierer, an ecology and evolutionary biology professor at the University ... Read More

Ancient whodunit may be solved: The microbes did it!

Methane-producing microbes may be responsible for the largest mass extinction in Earth’s history.

Evidence left at the crime scene is abundant and global: Fossil remains show that sometime around 252 million years ago, about 90 percent of all species on Earth were suddenly wiped out — by far ... Read More

ASM GM 2014 - Bacteria in Urine Could Cause Overactive Bladder

Contrary to popular belief, urine is not sterile and the bacteria in it may be associated with overactive bladder (OAB) in some women. Presenters will discuss their research ... Read More

Pictures Considered #17. The Meselson-Stahl Experiment

Described as the “Most Beautiful Experiment In Biology” the demonstration by Meselson and Stahl that DNA replicates semiconservatively is one of the major landmarks in the genesis of modern biology. And indeed it is most pleasing, both visually and cerebrally.

By semiconservative is meant tha... Read More

Methane-Munching Microorganisms Meddle with Metals

On the continental margins, where the seafloor drops hundreds of meters below the water’s surface, low temperatures and high pressure lock methane inside ice crystals. Called methane hydrates, these crystals are a potential energy source, but they are also a potential source of global warming if... Read More

Terms of Biology: The Pan-Genome

A still somewhat unfamiliar term is floating around: the pan-genome. In 2005, Tettelin et al. coined the term along with genome analyses of eight Streptococcus agalactiae strains, and Merry introduced it to this blog, some time back already. Today, a keyword search in PubMed returns roughly 200 ... Read More

In sub-Sahara, foot and mouth disease moves over short distances

You probably remember foot and mouth disease (FMD) from the 2001 outbreak in the UK that prompted the culling of over 10 million sheep and cattle, but the disease affects livestock all over the world. It's a particular problem in Africa, where wildlife that harbor the picornavirus that causes FM... Read More

Innocence by Viral Tagging - Finalist in Ocean 180 Video Challenge

Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in global nutrient cycling. Despite their ecological importance, little is known about how viruses interact with their hosts due to the dif... Read More

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