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Toxoplasma parasite's greedy appetite may be its downfall

Toxoplasma gondii is estimated to chronically infect nearly one-third of the world's population, causing the condition Toxoplasmosis. It is most commonly associated with handling cat feaces and is a particular threat to pregnant women and immune-compromised individuals, such as HIV/AIDS patients... Read More

The bacteria-fighting super element that’s making a comeback in hospitals: copper

Ancient Egyptians used copper to sterilize chest wounds and drinking water. Greeks, Romans and Aztecs relied on copper compounds to treat burns, headaches and ear infections. Thousands of years later, the ancient therapeutic is being embraced by some hospitals because of its ability to kill bact... Read More

BacterioFiles 244 - Rabbit Viruses Exploding Cancer

This episode: A conversation with Audiommunity hosts about a rabbit virus that may help treat cancer while preventing the treatment from killing the patient!


(39.2 MB, 42.9 minutes)


Show notes: 
Read More

Rapid testing for TB aims to reduce drug resistance, lower mortality rate

Researchers at University of California, San Diego School of Medicine have documented the accuracy of three new tests for more rapidly diagnosing drug-resistant forms of tuberculosis (TB), which are much harder and more expensive to treat and which, experts say, represent a major threat to globa... Read More

A collection of polioviruses

In midsummer 1986, five years after starting my poliovirus laboratory at Columbia University, I received a letter from Frederick L. Schaffer, a virologist at the University of California, Berkeley, asking if I would like to have his collection of poliovirus stocks. He was retiring and the sample... Read More

TWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.


Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. E... Read More

Ebola post-crisis: Lessons for improving global health security

WASHINGTON (Sept. 11, 2015) - The O'Neill Institute for National and Global Health Law fall colloquium series continues Wednesday, Sept. 16 with a focus on Ebola. Read More

Wasps do a gain-of-function experiment in caterpillars

Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More

TWiP 103: Scroll down, please

The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.


Hosts:  Read More

New Virus Identified in Blood Supply

Washington, DC – September 22, 2015 - Scientists have discovered a new virus that can be transmitted through the blood supply. Currently, it is unclear whether the virus is harmful or not, but it is related to hepatitis C virus (HCV) and human pegivirus (HPgV), the latter of which was formerly k... Read More

Sugar governs how antibodies work in the immune system

The immune system is our biological defense shield. Antibodies protect the organism against invading pathogens such as viruses or bacteria. In the case of certain autoimmune diseases, however, this defense behavior is misdirected: The antibodies don't just target foreign substances; they also at... Read More

A new virus in liver cancer

More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus. Researchers at Inserm, the Paris Public Hospitals (AP-HP), Paris Desc... Read More

Armed malaria protein found to kill cancer cells

A new type of cancer therapy based on seemingly unrelated elements of malaria and cancer is showing promise for development. Kairos Therapeutics, a Vancouver-based biotech company spun-out of The Centre for Drug Research and Development (CDRD), has partnered with VAR2 Pharmaceuticals to advance ... Read More

Sexual transmission of Ebola virus in Liberia confirmed using genomic analysis

A suspected case of sexual transmission of Ebola virus disease (EVD) in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by U.S. Army scientists in collaboration with the Liberian Institute for Biomedical Research (LIBR). Read More

TWiM 117 Letters

Jessica writes:
I just finished listening to Chewates and Coconuts and was so elated to hear about the open access paper comparing the Soybean Oil, Beef Tallow, and Coconut Oil effects on fungal colonization. I am a biologist by education, but I also have quite the “Crun... Read More

Vaginal Microbes Influence Whether Mucus Can Trap HIV Virus

Washington, DC —October 6, 2015— HIV particles are effectively trapped by the cervicovaginal mucus from women who harbor a particular vaginal bacteria species, Lactobacillus crispatus. The findings, published this week in mBio, an online open-access journal of the American Society for Microbiolo... Read More

New Ebola cases in single digits another week, says WHO

DAKAR, Senegal - New Ebola cases were in the single digits another week, the World Health Organization said Wednesday, showing that contact tracing efforts are yielding results.

Read More

BacterioFiles 249 - Spores Survive Spaceship Scorching

This episode: Bacterial spores can survive atmospheric entry on an artificial meteorite!


(10.7 MB, 11.25 minutes)


Show notes: 
J... Read More

Killing Dormant HIV with Cancer Drug

BOC Sciences-Recently Scientists found a new way to kill the hiding and dormant Human Immunodeficiency Virus( HIV) by employing a type of cancer drug, which is proved very effective but still waiting for further trial and approval by the US FDA. Read More

In very ill, probiotics don't prevent 'superbugs' from colonizing intestinal tract

Compared with routine medical care, probiotics administered to critically ill patients in intensive care units showed no benefit in preventing the colonization of drug-resistant microbes in the intestinal tract, according to new research at Washington University School of Medicine in St. Louis. Read More
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