Vincent, Dickson, and Daniel discuss identification of an erythrocyte protein essential for invasion of Plasmodium falciparum, and introduce a new case study.
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The TWiPanosomes solve the case about the Young Woman who Went to Belize, and relate how sandfly saliva skews the immune response and increases risk of cutaneous leishmaniasis.
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This episode: Engineering Salmonella strains that kill cancer cells but leave healthy ones alone!
(7.9 MB, 8.5 minutes)
Host: Vincent Racaniello
Guest: Katherine A. High
Vincent speaks with Katherine High about her... Read More
This episode: Bacteria are important for a good immune response to unadjuvanted influenza vaccines!
(14.6 MB, 16 minutes)
This episode: Archaea living in the deep ocean (and their viruses) have clever ways to maintain diversity and adaptability!
(10.3 MB, 11.25 minutes)
This episode: Bacteria can convert soluble uranium to an insoluble form, and distinguish between different isotopes!
(8.2 MB, 8.9 minutes)
Current smoking cessation aids fail in 80 to 90 percent of smokers. The idea behind this therapy would be to destroy nicotine before it reaches the brain—depriving a person of the “reward” of nicotine that can trigger relapse into smoking. Pseudomonas putida, a bacterium typically found in tobac... Read More
This episode: Don't have immunity? Create your own! Scientists engineer cells to destroy their HIV infections using the bacterial immune system!
(14.5 MB, 15.8 minutes)
In 2011, the NIH Clinical Center had a cluster of infections of a pathogen that tops the CDC's list of urgent threats: antibiotic-resistant Klebsiella pneumoniae. This bacteria, which can cause bloodstream and other infections, has recently developed resistance to the class of antibiotics kno... Read More
COLUMBIA, Mo. - HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges for researchers. Now, scientists at the University of M... Read More
Vincent, Dickson, and Daniel solve the case about the 33 year old Chinese male with watery diarrhea, and discuss whether arsenic in drinking water might lead to treatment failures for Leishmania infections.
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What do you get when you kiss a Petri dish? Bacteria and yeast colonies that grow into a pretty collage composed of different colors and morphologies. This is an LB agar plate incubated at room temperature for several days. Read More
Vincent, Dickson, and Daniel explain how trypanolytic factor forms membrane channels to lyse trypanosomes, and present a new case study.
Nishal Govindji-Bhatt, Post-doctoral Research Associate at the University of Manchester, United Kingdom, and Curtis Dobson, PhD, University of Manchester, discuss how to best avoid eye infection caused by poor contact lens case cleaning.
CHICAGO -- While studying Yersinia pestis, the bacteria responsible for epidemics of plague such as the Black Death, Wyndham Lathem, Ph.D., assistant professor in microbiology-immunology at Northwestern University Feinberg School of Medicine, found a single small genetic change that fundamentall... Read More