I teach Microbiology at the University of Puget Sound every fall semester. The swiftly changing field of microbiology has depth and breath...and I was interested to learn what my students thought of the topic at the beginning of the first day of class. We will revisit this subject at the end o... Read More
Lung ultrasound has been shown to be highly effective and safe for diagnosing pneumonia in children and a potential substitute for chest X-ray, according to a study conducted at the Icahn School of Medicine at Mount Sinai. Results are currently published in the medical journal Chest. Read More
CHAPEL HILL, N.C. - Investigators in the Division of Infectious Diseases at the University of North Carolina School of Medicine have clearly demonstrated that HIV infects and reproduces in macrophages, large white blood cells found in the liver, brain and connective tissues of the body. This dis... Read More
CHAMPAIGN, Ill. -- A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say. Read More
Bacillus anthracis had been studied by multiple countries as a potential biological weapon because of the stability of its spores and its ability to cause acute pulmonary disease. While offensive anthrax weapons development programs were halted in the United States and United Kingdom in the ... Read More
Three young inventors and students at Stanford University are working to develop proteins that fight antibiotic resistant bacteria. They are optimistic they have found something that works. The proteins the team is developing attack "something that's essential to bacterial survival". But they wo... Read More
Dear Vincent and hosts of TWIM,
I am a long time listener and fan of your weekly TWIM podcasts. I really enjoyed the latest episode in which you discussed a paper by Kelly Wrighton and colleagues, and was especially... Read More
Four years to the day after filming 'Threading the NEIDL', Vincent and Alan return to the National Emerging Infectious Diseases Laboratories BSL4 facility at Boston University where they speak with science writer David Quammen during the Emerging Infectious Disea... Read More
Of all the scientific results that my laboratory has produced over the years, I am most satisfied by those that maximally benefit the field. In this category falls the assay for determining the titer of Zika virus in plaque forming units per milliliter.
In ‘Counting Zika Virus’ I described o... Read More
Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016... Read More
Many people with Parkinson’s disease also experience digestive symptoms (like constipation) for some time before their diagnosis. But until recently, research on the degenerative disease and how to treat it has focused on understanding how Parkinson’s works in the brain.
In a new study out th... Read More
Engineers have developed a rapid, low-cost genetic test for Zika. The $2 device, about the size of a soda can, doesn’t require electricity or technical expertise and only needs a bit of saliva. Read More
The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.
Hosts: Read More
Philadelphia, PA, February 2, 2016 - Influenza is significantly associated with an increased risk of new-onset atrial fibrillation, which could be reduced through influenza vaccination, according to new findings reported HeartRhythm. Read More
I have worked on polio virus in my laboratory at Columbia University for 35 years. When that virus is eradicated--perhaps in the next few years--we will have to destroy all of our virus stocks. When that happens, I can either go home, or find another virus.
When Zika virus stepped into the w... Read More
Scientists from The University of Texas at Austin, the Stanford University School of Medicine and two other institutions have discovered that bacteria have a system that can recognize and disrupt dangerous viruses using a newly identified mechanism involving ribonucleic acid (RNA). It is similar... Read More
The immune system exercises constant vigilance to protect the body from external threats--including what we eat and drink. A careful balancing act plays out as digested food travels through the intestine. Immune cells must remain alert to protect against harmful pathogens like Salmonella, but th... Read More
Can Zika virus be sexually transmitted? Perhaps in very rare cases, but the main mode of transmission is certainly via mosquitoes. That’s why I’ve shamelessly stolen a quote on this topic from Dr. William Schaffner of Vanderbilt University: Mosquito transmission is the highway, whereas sexual tr... Read More
As we highlighted in our previous blog, antibiotic stewardship – the careful use of appropriate antibiotic administration – can have positive effects. A small change from a difference in clinical lab reporting led to less drug use, which led to fewer drug-resistant infections. When we think of a... Read More
Zika's hypothesized attraction to human neural stem cells may come from its ability to hijack a protein found on the surface of these cells, using it as an entryway to infection. In Cell Stem Cell on March 30, researchers at the University of California, San Francisco show that the AXL surface r... Read More