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Fungus Causing Fatal Infections in Hospitalized Patients Has Unique Growth Patterns

Washington, DC – August 17, 2016 – The multidrug-resistant yeast Candida auris, which has caused fatal infections in some hospitalized patients, has at least two different growth patterns and some of its strains are as capable of causing disease as the most invasive type of yeast called Candida ... Read More

Is brushing your teeth harming your gut microbiome?

In the 1960’s, the microbicide triclosan, was introduced in the United States, and soon after, human weight started to increase dramatically. For some time, researchers have wondered whether triclosan could have played a role in disrupting endocrine dysfunction and contributing to the obesity ep... Read More

TWiP 116: One drug to rule them all

The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment of leishmaniasis, Chagas diseases, and sleeping sickness.


Hosts: Vincent Racaniel... Read More

TWiV 395: The cancer thief

From ASV 2016 at Virginia Tech, Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy - using viruses to treat cancers. 


Hosts:  Read More

Testing the evolution of resistance by experiment

One of the hallmarks of bad science writing is the claim that any research to do with bacteria will lead to new antibiotics. In this case, however, the scientists backed up their claim. They took bacteria notorious for nosocomial infections (Pseudomonas aeruginosa) and exposed them to a toxin, ... Read More

BacterioFiles 265 - Predator Protein Protects Predator

This episode: Predatory bacteria have a particular protein that protects them from their own prey-damaging enzymes!


(7.3 MB, 7.9 minutes)


Show notes: 
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Burkholderia multivorans evolves in bursts in the lungs of cystic fibrosis patients

Leonilde M. Moreira, PhD, has been studying the Burkholderia complex for 15 years. The bacteria, known for causing pneumonia or septicemia in some individuals, can survive for prolonged periods in moist environments. During the last 10 years, it has become one of the more predominant bacteria se... Read More

Vibrio cholerae population structure changes in a matter of weeks

Although the Gram-negative bacterium Vibrio cholerae (right) is normally associated with human pathogenic disease, most V. cholerae cells spend their lives in an aquatic environment, and only a few of the many serotypes are able to cause disease. When strains acquire the right genetic makeup – s... Read More

Investigators Map Genomes of Three Historically Important Zika Strains

Washington, DC - August 18, 2016 - A team of researchers from Utah State University, Logan, has characterized the consensus genome sequences of three historically important Zika virus strains. This work is an important step towards developing antiviral therapeutic and preventive strategies again... Read More

TWiV 407: Tar Heels go viral, part two

In the second of two shows recorded at the University of North Carolina in Chapel Hill, Vincent meets up with faculty members to talk about how they got into science, their research on RNA viruses, and what they would be doing if they were not scientists.


Host:  Read More

TWiV 403: It's not easy being vaccine

The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine.


Hosts:  Read More

TWiV 399: Zika la femme

The latest Zika virus news from the ConTWiVstadors, including a case of female to male transmission, risk of infection at the 2016 summer Olympics, a DNA vaccine, antibody-dependent enhancement by dengue antibodies, and sites of replication in the placenta.


Hosts:  Read More

TWiV 400: Harold '400' Varmus, a scientist for all seasons

The TWiV team is together in New York City for a conversation with Nobel Laureate Harold Varmus about his remarkable career in science.


Hosts: Vincent Racaniello Read More

Insecticide-treated nets may still prevent malaria despite mosquito resistance

Insecticide-treated nets may still help prevent malaria despite mosquitoes developing resistance, according to a new study published in Parasites & Vectors. Read More

Using citizen science to engage students

Scientists and science educators now recognize the value in explaining what fields don’t understand, in addition to facts supported by years of experimental data. Citizen science projects, which emphasize accessibility of scientific technologies and methods for everyone, allow people without yea... Read More

TWiM 134 Letters

Nathan writes:
Dear Vincent, Elio, Michele & Michael,
 
Thank you all for the wonderful podcast!  It’s a great gift to humanity and science communication.  It would be great if you could discuss the really interesting paper by Din et al recen... Read More

Microbial communication over the airwaves

Jean-Paul Latgé originally wanted to know if he could test the breath of patients with Aspergillus infections for volatile compounds produced by the fungus. His group at the Pasteur Institute in Paris thought this might be a new way of diagnosing fungal culprits like Aspergillus fumigatus that o... Read More

A biofilm model that accounts for cell aggregates

Whether you’ve Google-searched “biofilm” to learn more yourself, taken courses covering the subject, or are deeply embedded in biofilm-related research, you’ve probably encountered a model similar to the one below, which represents biofilm maturation. In the current model, a biofilm begins with ... Read More

Applications of Clinical Microbial Next-Generation Sequencing - American Academy of Microbiology

The American Academy of Microbiology hosted an event at the National Press Club in February 2016 to disseminate the report, "Applications of Clinical Microbial Next-Generation Sequencing".

A panel of 4 speakers discussed real world applications of NGS and findings from the report, followed b... Read More

How immunity to RSV develops in childhood but deteriorates in adults

The leading infectious cause of severe respiratory disease in infants, respiratory syncytial virus (RSV), is also a major cause of respiratory illness in the elderly. Approved vaccines do not yet exist, and despite the development of partial immunity following infection during childhood, individ... Read More
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