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Table Top swab

Swab taken from the lab table top and incubated on TSA for 48 hrs, left at room temperature for 72 hrs then held at refrigerated temperature for a month. Pictured is one of the resulting fungal growths: white with no spore formation, droplets can be seen as possible result of respiration. Read More

Staining of Unknown Fungal sp.

While isolating organisms growing in a water system a dark Fungal growth was noted. I love isolating fungi and staining them in a manner that produces contrast among the hyphae. This fungi is yet to be identified but through the lense of a microscope it looks comparable to a tree in the fall a... Read More

Announcing ASM's Agar Art 2016 Winners

Thank you to everyone who created a log phase masterpiece, to our esteemed judges, and to everyone who voted for People's Choice on Facebook! We received 117 amazing entries from 26 countries and 17 U.S. states. Special congratulations to our winners! View this year’s winners... Read More

BacterioFiles 253 - Probiotics Promote Protective Pathway

This episode: In mice and fruit flies, Lactobacillus species induce gut cells to protect themselves from reactive oxygen compounds!


(8.2 MB, 8.9 minutes)


Show notes: 
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BacterioFiles 258 - Transformed Toxin Translocates Treatments

This episode: Bacterial toxins could be modified to deliver life-saving proteins into neurons!


(11.1 MB, 12.1 minutes)


Show notes: 
Journal Paper:

Chen C, Przedpelski A, Tepp WH, Pellett S, Johnson EA, Barbieri JT. 2015.... Read More

TWiM #130: Interkingdom interactions at ASM Microbe

The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.


Hosts: Read More

Largest HIV transmission study conducted

A new study has found that neither gay men nor heterosexual people with HIV transmit the virus to their partner, provided they are on suppressive antiretroviral treatment.



The PARTNER study, which is the world's largest study of people with HIV who have had condomless sex with their HIV ... Read More

BacterioFiles 256 - Virus Versus Virus

This episode: Viruses can cause host cells to inhibit other viruses!


(8 MB, 8.75 minutes)


Show notes: 
Journal Paper:

Chiba S, Suzuki N. 2015. Highly act... Read More

BacterioFiles 254 - Clostridium Consolidates Combustibles Conversion

This episode: Engineering bacteria to convert cellulose directly into useful biofuels and chemicals can be tricky!


(13.9 MB, 15.2 minutes)


Show notes: 
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Microbes After Hours: The Necrobiome - Microbial Life After Death

What happens to us after we die?  A decomposing corpse becomes its own mini-ecosystem, hosting insects, scavengers and multitudes of microbes.  Microbes from the environment, the corpse, as well as the insects and scavengers are blended together and work to recycle tissues back to t... Read More

TWiM #132: Bacteria learn long division

Vincent, Elio, and Michele present cell division by longitudinal scission in an insect symbiont, and thermally activated charge transport in microbial nanowires.


Read More

BacterioFiles 255 - Colonizer Controls Carrier Cultivation

This episode: Some bacteria seem to cause slime mold amoebas to carry around other bacteria for food!


(12.4 MB, 13.5 minutes)


Show notes: 
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TWiM 131: Mice behaving badly

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.


Hosts: Vinc... Read More

TWiM #129: Dried and wrinkled, smooth and mucoid

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.


Image (right): Etest used to determin... Read More

MWV 105 - Understanding the Pathogenesis of the Emerging Zika Virus

Dr. Michael Diamond, 2016 Elizabeth O. King Lecturer, has worked for the past two decades investigating how viruses work, with a goal of defining basic principles of pathogenesis and host immune restriction. His talk in this podcast focuses on how his laboratory has studied three emerging mos... Read More

TWiM #133: Right under our noses

Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.


Hosts: Vincent Racaniello, Elio Schaechter, an... Read More

BacterioFiles 261 - Pilfered Parasitoid Proteins Protect Prey

This episode: Viruses domesticated by parasitoid wasps have transferred wasp genes to caterpillar victims, allowing them to survive deadly infections from other viruses! This means that Monarch butterflies are effectively naturally Genetically Modified Organisms (GMOs).


(13.8 MB, 15 m... Read More

BacterioFiles 259 - Fluke Froth Fosters Fester Fixing

This episode: I converse with Dr. Michael Smout about a liver fluke parasite could help heal chronic wounds more quickly!


(13.4 MB, 14.6 minutes)


Show notes: 
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TWiP 112: A NOD to a tricky helminth

The TWiP trio solve the case of the Woman from Washington Heights, and reveal how helminth infection protects mice deficient in the Crohn's disease gene NOD2 from intestinal disease by inhibiting colonization with an inflammatory bacterial species.


Hosts:  Read More

TWiP 111: Bug bites

The TWiP trio solve the case of the bug bites all in a row, and talk about a secreted Toxoplasma protein that is central to the parasite's manipulation of host cells.


Hosts: Vincent Racan... Read More

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