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Shigella Steals Host Nutrients... Economically

Intracellular pathogens face many daunting problems, among them how to obtain enough energy and nutrients for active growth while, preferably, keeping the host cell alive for as long as possible. This issue is especially acute for pathogens that grow at a fast rate and reach large numbers. When ... Read More

We'd all like to get to Mars. Let's make sure we don't get sick along the way.

While Hollywood loves to imagine humans encountering all manner of horrific monsters in the depths of space, the greatest threat to a long-term, manned space mission may not come with tentacles, or extra mouths, or an insatiable love for human flesh. It may, in fact, be the invisible microbes t... Read More

On the trail of the truffle flavour

German an French Scientists found out: Soil bacteria contribute to the taste and smell of white truffles.

Truffles, along with caviar, are among the most expensive foods in the world. Because they grow underground, people use trained dogs or pigs to find them. But the distinctive smell of tru... Read More

Millions of Doses of Ebola Vaccine to Be Ready by End of 2015

The World Health Organization (WHO) announced plans on October 24 to produce millions of doses of two experimental Ebola vaccines by the end of 2015.

Hundreds of thousands of doses should be available to help affected countries before the end of June, the WHO said at the conclusion of a meeti... Read More

Research shows mushroom extract, AHCC, helpful in treating HPV

A Japanese mushroom extract appears to be effective for the eradication of human papillomavirus (HPV), according to a pilot clinical trial at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

The results were presented at the 11th International Conference of ... Read More

#microMOOC Microbes around us (in Spanish)

Microbes around us is an introductory open on line course of microbiology. Key words are: bacteria, virus, biodiversity, microbial evolution, extremophiles, microbiota, rumen, nitrogen cycle, biotechnology, industrial microbiology, biodegradation, biofuel, microbial engineering, infectious disea... Read More

Promising compound rapidly eliminates malaria parasite

An international research collaborative has determined that a promising anti-malarial compound tricks the immune system to rapidly destroy red blood cells infected with the malaria parasite but leave healthy cells unharmed. St. Jude Children’s Research Hospital scientists led the study, which ap... Read More

A positive step forward on the road to mitochondrial donation

A new IVF technique, developed by scientists at the Wellcome Trust Centre for Mitochondrial Research at the University of Newcastle, could prevent mitochondrial disease being passed from mother to child, enabling families to have healthy genetically related children.

Click "source" to read mo... Read More

Small Things Considered Retrospective, December 2014

As is our custom at this time of year, we go over the material that has appeared in this blog over the last six months. Seems like a lot of stuff, but it’s the result of the work of quite a number of dedicated people, all of whom deserve our gratitude.

Structure and Function

Chromosome Org... Read More

Pictures Considered #21. Southern Blot

"... These results, gained with a novel method for blotting (E. M. Southern, manuscript in preparation), have also led to the identification of the Bam Hl recognition sequence". It is rather unusual to find unpublished work referred to in the abstract of a paper, to put it mildly. But this was e... Read More

In vivo generation of DNA sequence diversity for cellular barcoding

na Read More

Patient with exposure to Ebola arrives safely at NIH Clinical Center

A patient with exposure to the Ebola virus while in Sierra Leone has arrived safely at the NIH Clinical Center for observation and to enroll in a clinical protocol. Read More

Injectable 3D vaccines could fight cancer and infectious diseases

New findings show programmable biomaterials can be delivered using needle injection to induce an immune response and fight deadly diseases.

One of the reasons cancer is so deadly is that it can evade attack from the body's immune system, which allows tumors to flourish and spread. Scientists ... Read More

Immune cells proposed as HIV hideout don't last in primate model

Where does HIV hide? Antiretroviral drugs can usually control the virus, but can’t completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as... Read More

For enterics, adaptability could be an Achilles heel

In research published in Nature Chemical Biology, scientists from RIKEN in Japan have discovered a surprisingly simple mechanism through which enterics can adjust to the very different oxygen environments inside the human gut and outside. This research, which was led by Shigeyuki Yokoyama and Wa... Read More

Typhoid gene unravelled

People who carry a particular type of gene have natural resistance against typhoid fever according to new research published in Nature Genetics.

Lead researcher, Dr Sarah Dunstan from the Nossal Institute of Global Health at the University of Melbourne said the study is the first large-scale,... Read More

Genome sequenced of enterovirus D68 circulating in St. Louis

Researchers at Washington University School of Medicine in St. Louis have sequenced the genome of enterovirus D68 sampled from patients treated at St. Louis Children’s Hospital. Nationwide, the virus has spread rapidly in recent months and caused severe respiratory illness in young children, wit... Read More

Separate forms and nodules of bacteria growth

IMAGE OF DISTINCTION Nikon SMALL WORLD 2013 PHOTOMICROGRAPHY COMPETITION

Neil James Egan, PPG Industries, Electro-coat Quality Assurance
Cleveland, Ohio, USA

Subject Matter: Separate forms and nodules of bacteria growth (20x)
Technique: Stereomicroscopy

Click "source" to view image. Read More

H1N1 Influenza Virus Particles

Colorized transmission electron micrograph showing H1N1 influenza virus particles.

Credit: National Institute of Allergy and Infectious Diseases (NIAID) Read More

Altered milk protein can deliver AIDS drug to infants

A novel method of altering a protein in milk to bind with an antiretroviral drug promises to greatly improve treatment for infants and young children suffering from HIV/AIDS, according to a researcher in Penn State's College of Agricultural Sciences.

That's critical because an estimated 3.4 m... Read More
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