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Why CRISPR Doesn't Work in E. coli

We received this query:

»I enjoyed the article on your blog 'Six Questions About CRISPRs' by Merry Youle. I am an ex-lambdologist, having quit phage lambda in the early 70s and moved to GM-plants. There is one thing about CRISPR that I do not understand: Why did lambdologists not find CRISPR?... Read More

Should experimental drugs be used in the Ebola outbreak?

Risks and benefits of unproven treatments, as World Health Organization approves use in crisis.

Two Liberian doctors are set to become the first Africans to receive an experimental drug against the Ebola virus. The news comes as the World Health Organization concludes that it is ethical to us... Read More

First Ebola Case Diagnosed in the U.S.

Federal officials today announced the first case of Ebola diagnosed in the U.S. The male patient was admitted to Texas Health Presbyterian Hospital Dallas and placed in strict isolation on September 28 after flying from Liberia to visit family in north Texas. The patient left Liberia on Septembe... Read More

Flu virus key machine: First complete view of structure revealed

Scientists looking to understand – and potentially thwart – the influenza virus now have a much more encompassing view, thanks to the first complete structure of one of the flu virus’ key machines. Knowing the structure allows researchers to finally understand how the machine works as a whole, a... Read More

Smallpox Virus Found In Unsecured NIH Lab

Scientists cleaning out an old laboratory on the National Institutes of Health campus in Bethesda, Md., last week came across a startling discovery: vials labeled "variola" — in other words, smallpox.

Under international convention, there are supposed to be only two stashes of this deadly vir... Read More

Antibacterial Gene Transfer Across the Tree of Life

Though horizontal gene transfer (HGT) is widespread, genes and taxa experience biased rates of transferability. Curiously, independent transmission of homologous DNA to archaea, bacteria, eukaryotes, and viruses is extremely rare and often defies ecological and functional explanations. Here, we ... Read More

Ebola Gorilla Vaccine Could Prevent Human Outbreaks

Humans are not the only primates ravaged by the deadly Ebola virus. Chimps and gorillas are also susceptible to the disease. The current Ebola epidemic, the biggest in human history, may have started with the butchering of an infected fruit bat. But it just as easily could have come from a chimp... Read More

Antibiotic resistance mechanisms of clinically important bacteria.

Antibiotic resistance mechanisms of clinically important bacteria. Read More

Biochemistry detective work: algae at night

Photosynthesis is probably the most well-known aspect of plant biochemistry. It enables plants, algae, and select bacteria to transform the energy from sunlight during the daytime into chemical energy in the form of sugars and starches (as well as oils and proteins), and it involves taking in ca... Read More

Handling the cholera outbreak of 1854

This article discusses the famous pump handle that John Snow may or may not have had removed ... read the article to get the true story. From medical historian Peter Vinten-Johansen. Read More

colony pic. of K.oxytoca in the form of ASM(American society for microbiology).

this isolate is klebsiella oxytoca.
so, with the help of colony pic of klebsiella oxytoca written as ASM (american society for microbiology).
Media: mac-conkey agar
organisms: K.oxytoca
Incubation condtion:at37'c for 24hrs

Klebsiella oxytoca is a Gram-negative, rod-shaped bacterium that i... Read More

Airborne Environmental Isolate

Media is poured in bulk in our lab for classroom use. Although contamination is low we do see airborne contamination especially durning the rainy season. This is an unknown airborne environmental isolate on Mueller-Hinton agar exhibiting a single circular colony. White hyphal growth can be see... Read More

Biological Samples

ILSbio is the company of choice for research institutions, biotech organizations and pharma companies looking for high quality, documented biological samples to support their research. With a wide range of specimens types available including diseased tissue, FFPE, blood, and serum, collections c... Read More

Authorities Identify Highly Contagious Bird Flu Strain

Authorities found the H5N8 strain of bird flu at a poultry farm in the central Netherlands, the same highly contagious strain as found this month in Germany and which has prompted massive poultry culls in Asia.

Dutch authorities on Sunday said they had found the H5N8 strain of bird flu at a p... Read More

colony pic. of V.cholerae in the form of ASM(American society for microbiology).

this isolate is v. cholerae o1,so colony pic of v. cholerae written as ASM(american society for microbiology) in TCBS(thiosulphate citrate bile salt sucrose) media as sucrose fermenting yellow colonies.
organisms: V. cholerae o1
media:TCBS(thiosulphate citrate bile salt sucrose) media
incub... Read More

Incidence of childhood tuberculosis could be 25 percent higher than previous estimates

New estimates indicate that over 650,000 children develop tuberculosis (TB) every year in the 22 countries with a high burden of the disease -- almost 25 percent higher than the total number of new cases worldwide estimated by WHO in 2012. The research also suggests that about 15 million childre... Read More

Scientists develop ‘electronic nose’ for rapid detection of C-diff infection

A fast-sensitive “electronic-nose” for sniffing the highly infectious bacteria C-diff, that causes diarrhoea, temperature and stomach cramps, has been developed by a team at the University of Leicester.

Using a mass spectrometer, the research team has demonstrated that it is possible to ident... Read More

Schistosomas: Tropical parasite uses swim stroke not shared by any other creature

For many bacteria and parasites looking to get a load of the fresh nutritional bounty inside your body, the skin is the first and most important gatekeeper. Schistosomas, however, and burrow right on through. These waterborne blood flukes, responsible for 200 million total worldwide cases of Sch... Read More

Bacteria may have ability to reduce impact of diazepam on UK river environments

The natural photo degradation of diazepam (valium) and similar medicines – followed by bacterial breakdown – may reduce their potentially harmful impact on the UK’s freshwater environment, a team of researchers has said.

Diazepam – used to treat anxiety and other similar conditions – has been... Read More

Viral Switches Share a Shape

A hinge in the RNA genome of the virus that causes hepatitis C works like a switch that can be flipped to prevent it from replicating in infected cells. Scientists have discovered that this shape is shared by several other viruses—among them one that kills cancer cells.

That’s Seneca Valley v... Read More

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