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Facilitation of horizontal transfer of antimicrobial resistance by transformation of antibiotic-induced cell-wall-deficient bacteria

It is universally accepted that the use of antibiotics will lead to antimicrobial resistance. Traditionally, the explanation to this phenomenon was random mutation and horizontal gene transfer and amplification by selective pressure. Subsequently, a second mechanism of antibiotic-induced antimic... Read More

US Travelers Return Home With Tropical Disease. Will It Spread In The States?

If you happened to be reading state health departments’ outbreak announcements this past weekend, you might have seen something interesting.

(You don’t do this? Hmm.)

Three states — Rhode Island, North Carolina and Tennessee — all said that they have identified residents who have been diag... Read More

Progress in the fight against harmful fungi

A group of researchers at the Max F. Perutz Laboratories has created one of the three world's largest gene libraries for the Candida glabrata yeast, which is harmful to humans. Molecular analysis of the Candida glabrata fungus mutations led to the discovery of 28 new genes that are partly respon... Read More

The Result of the Microbiome Poll

What have we learned?

The various comments confirm that the term microbiome means different things to different people.

Lita points out that in the early days when HMP was formed, the NIH officially defined the human microbiome as “all of the microorganisms and their genes and genomes whic... Read More

How do they make it work? Genomic Revelations on a Bacterial Consortium

Do you ever look at a couple and wonder… ‘Why are they together? What does X see in Y. I just don’t get it. Is X in it only for the money’? Who doesn’t at times ponder about such matters? There’s practically an entire economy based on it. However, you didn’t find this article while waiting to ... Read More

A Cheap, Promising Way to Filter Water: Through A Twig

One way to avoid getting sick while traveling is to only eat fruit that you peel yourself, since plants can filter out bacteria and prevent it from traveling throughout their tissues. Well, why not apply this principle to filtering water directly? A team of scientists have done just that, testi... Read More

Bird flu 'danger zones' mapped

The "danger zones" in Asia which are vulnerable to a deadly bird flu have been mapped by scientists.

The virus, called H7N9, has infected 433 people mostly in China and has killed 62.

The study, published in Nature Communications, showed parts of Bangladesh, India and Vietnam could easily ... Read More

Source of Justian Plague Sequenced?

In a fascinating story that was presented on NPR by Nell Greenfieldboyce we learn that the source of the Justian Plague (541-543AD) was recently identified by sequencing blood extracted from the dental pulp of the teeth associated with two skeletons recovered from Munich. For many years it was... Read More

Bacteria: A day in the life

MIT study finds ocean bacteria follow predictable patterns of daily activity.

We are all creatures of habit, and a new MIT study finds ocean bacteria are no exception.

In a paper published this week in Science, researchers from MIT and elsewhere report that microbes in the open ocean follo... Read More

Airborne Environmental Isolate/Fungal view 1

An unknown airborne environmental isolate on Bile Esculin Agar (BEA) exhibiting a single circular colony. White hyphal growth with no spore formation. Clear to brownish exudate can be seen throughout the colony. This sample grew at refrigerated temperatures for several months. The agar surroun... Read More

SA vaccine cuts bacteria to size

South Africa has shown the world that a vaccine against the strains of bacteria that can cause deadly meningitis and pneumonia in children works.

A study published today in the New England Journal of Medicine, to coincide with world Pneumonia Day, records the country's success in reducing pne... Read More

Deadly Human Pathogen Cryptococcus Fully Sequenced

DURHAM, NC - Within each strand of DNA lies the blueprint for building an organism, along with the keys to its evolution and survival. These genetic instructions can give valuable insight into why pathogens like Cryptococcus neoformans -- a fungus responsible for a million cases of pneumonia and... Read More

ASM GM 2014 - This Week in Virology #286: Boston TWiV Party

The American Society for Microbiology hosted a live podcast of This Week in Virology with Vincent Racaniello with co-host Alan Dove that includes guests Paul Duprex, Director of Cell and Tissue Imaging Core, Boston University, National Emerging Infectious Diseases Laboratories (NEIDL), and Ju... Read More

Untapped Plant Microbiome Could Help Feed Billions

The Human Microbiome Project revealed tens of trillions of microbes residing in and on humans. Now scientists are taking a census of plant microbes—and not just the hundreds of billions found in soils. Distinct microbial communities live inside roots, on leaves and within flowers, and all in all... Read More

Drugs fail to reawaken dormant HIV infection

Scientists report that compounds they hoped would "wake up" dormant reservoirs of HIV inside immune system T cells -- a strategy designed to reverse latency and make the cells vulnerable to destruction -- have failed to do so in laboratory tests of such white blood cells taken directly from pati... Read More

A Letter to STC from Julian Davies

Bravo Randy Schekman!

I strongly support your comments on the tyranny of "impact factors" and I will be pleased to join in efforts to prevent the misuse of these ratings.

Impact Factors have become a symbol of terror for scientists in all disciplines and their use in promotion and other ... Read More

Vaccine-resistant polio strain discovered

The global initiative to eradicate poliomyelitis through routine vaccination has helped reduce the number of cases by more than 99% in 30 years. However, major epidemics are still occurring today. Researchers have identified the virus responsible for deadly and recent outbreaks, and have sequenc... Read More

Retrospective, December 2013

We continue our semi-annual ritual and post this quick tour of our featured blog posts published since June 2013.

Evolution

Microbial ‘Starstuff’. Associate blogger Gemma Reguera tells us how the remnants of a dying star become transmuted into microbial stuff, including cellular structures... Read More

Why a bacterium got its curve — and why biologists should know

Drawing from his engineering background, Princeton University researcher Alexandre Persat had a notion as to why the bacteria Caulobacter crescentus are curved — a hunch that now could lead to a new way of studying the evolution of bacteria, according to research published in the journal Nature ... Read More

Nocardia asteroides on Gram stain

Presence of Gram-positive, partially acid-fast rods, which have grown in branching chains resembling fungal hyphae. (Gram stain; original magnification, ×100). Image courtesy MicrobeWorld user Kyriakos Zaragkoulias, Specialty Registrar (StR) in Medical Microbiology at General Hospital of Thessal... Read More

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