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Malaria-carrying mosquitoes wiped out in lab with genetic method that creates male-only offspring

Scientists have modified mosquitoes to produce sperm that will only create males, pioneering a fresh approach to eradicating malaria. Since 2000, increased prevention and control measures have reduced global malaria mortality rates by 42 per cent, but the disease remains a prevalent killer espec... Read More

Researchers open door to new HIV therapy

BERKELEY — People infected with the Human Immunodeficiency Virus (HIV) can stave off the symptoms of AIDS thanks to drug cocktails that mainly target three enzymes produced by the virus, but resistant strains pop up periodically that threaten to thwart these drug combos. Researchers at the Unive... Read More

Recalling the Good in the Good Old Days

In its early days, ca. 1945-1965, molecular biology was a particularly collegial undertaking, characterized by free sharing of research data and a relative lack of egotistical behavior. The reason for this marvel may well have been that there was so much to discover—so many low hanging fruits—th... Read More

Bacteria show surprising number of genetic paths to survival

A boy with cystic fibrosis develops a chronic and potentially deadly Burkholderia dolosa infection in his lungs. Varieties of genetic mutations allow some strains of the bacteria to survive the dual assaults from his immune system and antibiotics, while others perish. Eventually, the strongest m... Read More

Source: Flight en route to Liberia to evacuate Americans infected with Ebola

According to CNN,a long-range business jet with an isolation pod left the United States for Liberia, where it will evacuate two Americans infected with Ebola.

Twitter exploded with questions about the deadly virus, which according to the World Health Organization is believed to have killed hu... Read More

UNC researchers discover new target for dengue virus vaccine

Using an experimental technique new to the dengue field, the labs of Ralph Baric, PhD, and Aravinda de Silva, PhD, showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue 3 to disable it. The finding, published in the Proceedings of... Read More

ASM GM 2014 - The Effect of Pancreatic Cancer on the Oral Microbiome

In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagno... Read More

Yes! We have no bananas? It could actually happen

Banana lovers take note: The world's supply of the fruit is under attack from a fungus strain that could wipe out the popular variety that Americans eat. "It's a very serious situation," said Randy Ploetz, a professor of plant pathology at the University of Florida who in 1989 originally discove... Read More

On Teaching

A graduate student came to my office recently to say that she was increasingly bothered by anxiety and the ‘terror’ of having to speak at laboratory meetings. She had also learned a month ago that she was expected to lecture to a class organized by her mentor. The thought of having to lecture to... Read More

colony of candida spp.

Colonies of candida species:

Media: HiCrome Candida Differential Agar
principle: Perry and Miller (1) reported that Candida albicans produces an enzyme b -N-acetyl- galactosaminidase and according to
Rousselle et al (2) incorporation of chromogenic or fluorogenic hexosaminidase substrates... Read More

Zaire ebolavirus in West Africa

Dr. Tom Solomon is Director of the Institute for Infection and Global Health at the University of Liverpool. In this video he speaks with Vincent Racaniello about the 2014 outbreak of Zaire ebolavirus in West Africa. Dr. Solomon discusses why the epidemic has spread, how it might be curtailed, t... Read More

New research reveals how bacteria construct tiny flagella ‘nanomachines’ outside the cell

Cambridge scientists have uncovered the mechanism by which bacteria build their surface propellers (flagella) – the long extensions that allow them to swim towards food and away from danger. The results, published this week in the journal Nature, demonstrate how the mechanism is powered by the s... Read More

Clinically Important Drug-Resistant Bacteria” .

"Clinically Important Drug-Resistant Bacteria” Read More

Growth on Manital Salt Agar of Staphylococcus aureus and staphylococcus epidermis isolated from wounds

These clinical isolates are from Medinipur Medical College. Read More

Amber discovery indicates Lyme disease is older than human race

Lyme disease is a stealthy, often misdiagnosed disease that was only recognized about 40 years ago, but new discoveries of ticks fossilized in amber show that the bacteria which cause it may have been lurking around for 15 million years – long before any humans walked on Earth.

The findings w... Read More

Gut Bacteria Lose their Tails to Evade Antibodies

New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.

In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More

MDR-TB: A Global Threat

In Pakistan prevalence and drug resistance of TB is on the rise. Late diagnosis and lack of resources are making the situation worse. In such a scenario molecular techniques such as PCR and hybridization would help in early diagnosis of TB and MDR TB leading to commencement of treatment at the r... Read More

Ebola genomes sequenced

Speedy analysis reveals mutations, insights into outbreak, along with clues to origin, spread.

Responding rapidly to the deadly outbreak of Ebola virus disease (EVD) in West Africa, a team of researchers from the Broad Institute and Harvard University, working with the Sierra Leone Ministry o... Read More

Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the “seesaw effect”: Taking advantage of the back door left open?

Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More

DIY Droplet Lens, finalist, 2014 Eureka Prize for Innovative Use of Technology

The traditional light microscope is bulky and expensive. Dr Tri Phan and Dr Steve Lee from the Garvan Institute of Medical Research and Australian National University used gravity to manufacture high-performance polymer lenses. These can be seamlessly integrated with 3D printing and mini-LEDs to... Read More

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