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Improving the effect of HIV drugs by the use of a vaccine

A vaccine containing a protein necessary for virus replication can boost an HIV-infected patient's immune system, according to clinical research published in the open access journal Retrovirology. This boost can result in increased effectiveness of antiretroviral drugs. Read More

TWiM 102 Letters

Dave writes:


TWIM Comrades--
I first want to compliment you on one of my most listened to podcasts, and one that I actually know what is being presented most of the time.


Now about the term Talmudic.
Do we need a name that is a legal commentary on th... Read More

TWiM #102: Happiness is the spore-formers in your gut

The TWiM team discusses evidence that serotonin synthesis is regulated by spore-forming members of the gut microbiota. Read More

HOW ZINC ‘JAMS UP’ THESE DRUG-RESISTANT MICROBES

New research from the University of Queensland has shown how zinc "tricks" an essentialmManganese-transport protein of S. pneumoniae into a shape in which it can't accept manganese. It is known that manganese is essential for S. pneumoniae infection to occur, so this research offers a chance to... Read More

‘VELCROED’ NANOPARTICLES TARGET HIV AND CANCER

University at Buffalo researchers have discovered a way to easily and effectively fasten proteins to nanoparticles by simply mixing them together. The biotechnology model is described in the journal Nature Chemistry. Read More

Describing a viral quasispecies

Virus populations do not consist of a single member with a defined nucleic acid sequence, but are dynamic distributions of nonidentical but related members called a quasispecies (illustrated at left). While next-generation sequencing methods have the capability of describing a quasispecies, the ... Read More

NIH funds 9 antimicrobial resistance diagnostics projects

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded more than $11 million in first-year funding for nine research projects supporting enhanced diagnostics to rapidly detect antimicrobial-resistant bacteria. The awardee institu... Read More

Paper and Phones Could Soon Diagnose Ebola and HIV for $1

Diseases such as HIV and Ebola are on the verge of being diagnosed almost instantly using paper-based technology costing less than $1. Read More

Stopping HIV in its tracks

Is the end of HIV near? Findings published this week in Antimicrobial Agents and Chemotherapy report that a novel, subdermal implant delivering potent antiretroviral (ARV) drugs shows extreme promise in stopping the spread of HIV. Read More

Staphylococcus aureus - BP Agar

The Baird Parker Agar is great to isolated Staphylococcus aureus, the colonies turn a deep black color that create an amazing contrast with the yellow of the medium. Read More

My global challenge video Myths about polio and its vaccination in Pakistan

My global challenge video.... Read More

TWiP 88: French foreign lesion

Vincent, Dickson, and Daniel discuss how a secreted protein from the protozoan parasite Theileria transforms its host cells via a cellular proto-oncogene.


Hosts:  Read More

Unprecedented microbial diversity reported in remote Amazonian tribe

April 17, 2015 - A multicenter team of U.S. and Venezuelan scientists, led by researchers from NYU Langone Medical Center, have discovered the most diverse collection of bodily bacteria yet in humans among an isolated tribe of Yanomami Indians in the remote Amazonian jungles of southern Venezuel... Read More

Streptococcus pyogenes

Throat swab of (5) years old child from emergency department for culture and sensitivity clinical summary scarlet fever.

Streptococcus pyogenes, or Group A Streptococcus, is a spherical, Gram-positive bacterium.[1] S. pyogenes displays streptococcal group A antigen on its cell wall and typic... Read More

Retroviral influence on human embryonic development

About eight percent of human DNA is viral: it consists of retroviral genomes produced by infections that occurred many years ago. These endogenous retroviruses are passed from parent to child in our DNA. Some of these viral genomes are activated for a brief time during human embryogenesis, sugge... Read More

Socialization proper task of the State

Socialization proper task of the State

The well-known judgment of the Constitutional Court December 2, 2010, (Background, No. 7, p. A), tells us that the education to which everyone is entitled and whose guarantee is for the government as their own task is not contracted for Therefore, a proc... Read More

Rising antibiotic shortages raise concerns about patient care

Shortages of key antibiotics, including gold-standard therapies and drugs used to treat highly resistant infections, are on the rise, according to a new study of shortages from 2001 to 2013 published in Clinical Infectious Diseases and available online. The trends raise serious concerns about th... Read More

Anti-HIV antibody shows promise in first human study

A single infusion of an experimental anti-HIV antibody called 3BNC117 resulted in significantly decreased HIV levels that persisted for as long as 28 days in HIV-infected individuals, according to Phase 1 clinical trial findings published online today in Nature. Read More

Pictures Considered #25. Getting A Ride

From Moselio Shaechter of ASM's Small Things Considered:

"A recent review article deals with the fascinating phenomenon of pathogens exiting from their host cell. Sometimes, one pathogen helps another one in transmission to the next host. In one case, a Candida albicans hypha caught in the ac... Read More

How two microbes helped neuroscience

How two unlikely microbes led to the development of one of today's most promising brain research techniques -- optogenetics -- which is being used to study many diseases including schizophrenia and Parkinson's. Read More
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