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DNA binding by C. crescentus VapBC1 (video)

The video shows the structural changes in the Caulobacter crescent VapBC1 protein complex during DNA binding, including how the antitoxin “tails” containing the protein palindromic sequences switch positions.

Link to the research article in Nucleic Acids Research http://nar.oxfordjournals.org... Read More

Deadly sleeping sickness set to be eliminated in 6 years

Gambian sleeping sickness -- a deadly parasitic disease spread by tsetse flies -- could be eliminated in six years in key regions in the Democratic Republic of Congo (DRC), according to new research by the University of Warwick

Kat Rock and Matt Keeling at the School of Life Sciences, with co... Read More

For the first time, researchers identify key proteins that may make Zika so deadly

Until it burst onto the scene earlier this year, Zika was an obscure, little-known virus. As a result, scientists know little about how it works. Over the past year, they have learned that it can cause a range of dangerous health problems, including birth defects such as microcephaly and neurolo... Read More

A superbug resistant to every available antibiotic in the U.S. kills Nevada woman

If it sometimes seems like the idea of antibiotic resistance, though unsettling, is more theoretical than real, please read on.

Public health officials from Nevada are reporting on a case of a woman who died in Reno in September from an incurable infection. Testing showed the superbug that ha... Read More

Fungus-infecting virus could help track spread of white-nose syndrome in bats

A newly discovered virus infecting the fungus that causes white-nose syndrome in bats could help scientists and wildlife agencies track the spread of the disease that is decimating bat populations in the United States, a new study suggests.

Regional variations in this virus could provide clue... Read More

Microbiomes in far-flung places: characterizing the arctic Inuit gut microbiome

The hamlet of Resolute Bay is a tiny Arctic village in the Nunavut territory of Canada with a population that hovers at or below 300. Over hundreds of perhaps even thousands of years, the traditional Inuit diet in Resolute Bay and elsewhere has been dictated by the Arctic environment. The diet i... Read More

How to be a successful food borne pathogen: step 1, grow on food

Food microbiology is an important issue we cover on this blog, because food safety is vital to prevent foodborne illness. The use of technologies like whole-genome sequencing help identify and pinpoint the source of microbial contaminants, but how do microbes become contaminants in the first pla... Read More

Ancient Chinese malaria remedy fights TB

A centuries-old herbal medicine, discovered by Chinese scientists and used to effectively treat malaria, has been found to potentially aid in the treatment of tuberculosis and may slow the evolution of drug resistance.

In a promising study led by Robert Abramovitch, a Michigan State Universit... Read More

Threading the RSV vaccine needle

Crafting a vaccine against RSV (respiratory syncytial virus) has been a minefield for 50 years, but scientists believe they have found the right balance.

Researchers at Emory University School of Medicine and Children's Healthcare of Atlanta report that they have engineered a version of RSV t... Read More

El Niño fueled Zika outbreak, new study suggests

Scientists at the University of Liverpool have shown that a change in weather patterns, brought on by the 'Godzilla' El Niño of 2015, fuelled the Zika outbreak in South America.

The findings were revealed using a new epidemiological model that looked at how climate affects the spread of Zika ... Read More

UTMB develops an oral vaccine against Salmonella

Researchers from The University of Texas Medical Branch at Galveston have developed a vaccine against salmonella poisoning designed to be taken by mouth. The findings are detailed in an article published in Frontiers in Cellular and Infection Microbiology.

In earlier studies, the UTMB researc... Read More

10 Things You Need to Know about mSphereDirect

mSphereDirect is an exciting new pathway to publish your research! This groundbreaking new submission path puts you in control of getting your original research reviewed and published as soon as possible. We’ve prepared the most important things to keep in mind while preparing your manuscript s... Read More

Sunlight offers surprise benefit -- it energizes infection fighting T cells

Sunlight allows us to make vitamin D, credited with healthier living, but a surprise research finding could reveal another powerful benefit of getting some sun.

Georgetown University Medical Center researchers have found that sunlight, through a mechanism separate than vitamin D production, e... Read More

Flaviviruses unexpectedly shut off host translation

It was a peer review request that got Alessia Ruggieri and her group at University of Heidelberg to look more closely at how Dengue virus manipulates the cellular translation and stress machineries during infection.

In a previous study, Ruggieri showed that Hepatitis C virus infection induced... Read More

Super “Resolution”: Reflections on Microscopy in the New Year

As we shake off the holidays, 2017 brings a new opportunity for personal reflection. For many trainees, it is also a great time to focus one’s professional goals, including those related to microbiology and microscopy. In celebration of the new year, I’d like to reflect on some of the advanced m... Read More

MdlM119: Las secuencias CRISPR: Su descubrimiento y sus futuras aplicaciones

El sistema CRISPR, su descubrimiento y posibles applicaciones:  En el episodio de hoy contamos con la presencia del Dr. Francisco Mojica de la Universidad de Alicante. 


Aprovechamos una visita suya a la Universidad de Puerto Rico para poder compartir la trayectoria de uno de... Read More

Infant's prolonged infection reveals mutation that helps bacteria tolerate antibiotics

A life-threatening infection in an infant with leukemia led to a St. Jude Children’s Research Hospital discovery of how prolonged infection sets the stage for bacterial persistence despite antibiotic susceptibility

The quest to understand a prolonged infection in an infant being treated for l... Read More

Bacterial communities of the female genital tract impact HIV infection risk

A team of researchers from the Massachusetts General Hospital (MGH) and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract of healthy South African women is associated with a more than four-fold increase in the risk of acquiring HI... Read More

IDRI contributes to first point-of-care Chagas disease diagnostic for US

With Chagas disease becoming more prevalent in the United States, a diagnostic to quickly and easily detect infection is needed. Today, IDRI (Infectious Disease Research Institute) announces that a fusion antigen it developed and patented is being used as part of a Chagas disease diagnostic test... Read More

Bacterial protein structure could aid development of new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don’t. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.

Yet one step in the process has remained a mystery because the molecu... Read More
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