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Researchers Find New Way to Kick Out HIV From Infected Cells

The technique addresses the problem of hidden reservoirs of HIV in the body, and could herald a new way of battling the viral infection.

Once HIV invades the body, it doesn’t want to leave. Every strategy that scientists have developed or are developing so far to fight the virus – from powerf... Read More

Land of the bacteria-eaters

For hospital workers an outbreak of harmful bacteria in the wards is a nightmare, but what gives bacteria nightmares?

Perhaps the prospect of being eaten alive by a kind of viral parasite called a bacteriophage (bacteria eater): unlike antibiotics, which some bacteria have evolved a resistanc... Read More

U.K. Supermarket To Run On Electricity Made From Its Own Rotting Food

The joys of anaerobic digestion

One U.K. grocery store plans to power itself using biogas harvested from its own unsold, rotting produce. Yum.

A Sainsbury's store in Cannock in central England is getting access to anaerobic digesters. The store plans to use electricity solely from the dige... Read More

Microbe, Enzyme or Mineral? A Riddle in the Soil

When most people look at soil, they just see dirt. When I look at soil, I see billions of microorganisms crawling atop one another, consuming the dead in a feasting frenzy that stops for nothing save a deep freeze. I see microbes and their enzymes, the digestive juices that break down, transform... Read More

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs

A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells.

A new study from MIT materials scientists reveals that these nanoparticles enter cells by taking advantage of a route normally used in vesicle-... Read More

BacterioFiles 175 - Bacteria Build Better Biofilms

This episode: Engineered bacteria can be made to produce many different useful kinds of biofilm!


(10.5 MB, 11.5 minutes)


Show notes: 
News item 1/ Read More

Study examines therapeutic bacteria’s ability to prevent obesity

A probiotic that prevents obesity could be on the horizon.

Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, Vanderbilt University investigators have discovered.

“Of course it’s hard to spec... Read More

Bacteria: A day in the life

MIT study finds ocean bacteria follow predictable patterns of daily activity.

We are all creatures of habit, and a new MIT study finds ocean bacteria are no exception.

In a paper published this week in Science, researchers from MIT and elsewhere report that microbes in the open ocean follo... Read More

Clear halo in petri dishes by Acetobacter pasteurianus

Growth of Acetobacter pasteurianus on glucose, yeast extract, calcium carbonate, ethanol medium.
Formation of acetic acid from ethanol oxidation is shown by a clear halo around bacterial growth due to dissolution of calcium carbonate.
Organism: Acetobacter pasteurianus. Incubation conditions:... Read More

HIV, malaria, and tuberculosis: Success of the Millennium shown in most comprehensive study to date

Accelerated progress against the global burden of HIV, malaria, and tuberculosis (TB) has been made since 2000 when governments worldwide adopted Millennium Development Goal 6 to combat HIV/AIDS, malaria, and TB. New estimates from a major new analysis show that worldwide, the number of people l... Read More

Drug Combo Can Sure Hepatitis C in Patients With HIV

A new combination drug therapy cures chronic hepatitis C in most patients also infected with HIV—and without the side effects of current treatments.

The advance is important, researchers say, because about a third of HIV patients in the United States also have hepatitis C. There are an estima... Read More

Ancient genetic material from caries bacterium obtained for the first time

A UAB research concludes that the Streptococcus mutans, one of the principal bacteria causing dental caries, has increased the changes in its genetic material over time, possibly coinciding with dietary changes linked to the expansion of humanity.

Click "source" to read more. Read More

The virus detective who discovered Ebola in 1976

Nearly 40 years ago, a young Belgian scientist travelled to a remote part of the Congolese rainforest - his task was to help find out why so many people were dying from an unknown and terrifying disease.

In September 1976, a package containing a shiny, blue thermos flask arrived at the Instit... Read More

Viral relics show cancer's 'footprint' on our evolution

Cancer has left its 'footprint' on our evolution, according to a study which examined how the relics of ancient viruses are preserved in the genomes of 38 mammal species.

Viral relics are evidence of the ancient battles our genes have fought against infection. Occasionally the retroviruses th... Read More

TWiM 83 Letters

Matt writes:


Hello TWiM team,

It was great seeing some of you at ASM last week in Boston either in passing between sessions or at the live TWiV episode. I have a few questions about the ASM meeting:
What was something that you all took away from ASM th... Read More

Microbial to Human Cell Ratio: Just Bragging Rights?

Microbiota buffs repeat it often these days, proudly reminding the public that the microbial cells associated with humans outnumber their host cells by a ratio of ten-to-one. In his letter in the February 2014 Microbe, however, Judah L. Rosner of the National Institutes of Health (NIH) makes a s... Read More

Smallpox Virus Found In Unsecured NIH Lab

Scientists cleaning out an old laboratory on the National Institutes of Health campus in Bethesda, Md., last week came across a startling discovery: vials labeled "variola" — in other words, smallpox.

Under international convention, there are supposed to be only two stashes of this deadly vir... Read More

New research from Africa on pharmacomicrobiomics

The Human Microbiome Project (HMP) is a global initiative to identify and characterize the microorganisms present at multiple sites in the human body. An international team of researchers reports on new ways to harness the results of the HMP and discusses how changes in the microbiome might affe... Read More

Diseases of Another Kind

The drought that has the entire country in its grip is affecting more than the color of people’s lawns. It may also be responsible for the proliferation of a heat-loving amoeba commonly found in warm freshwater bodies, such as lakes, rivers and hot springs, which the drought has made warmer than... Read More

Incidence of childhood tuberculosis could be 25 percent higher than previous estimates

New estimates indicate that over 650,000 children develop tuberculosis (TB) every year in the 22 countries with a high burden of the disease -- almost 25 percent higher than the total number of new cases worldwide estimated by WHO in 2012. The research also suggests that about 15 million childre... Read More
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