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Ebola crisis: A doctor's view from Sierra Leone

West Africa's Ebola epidemic, the deadliest on record, presents particular challenges for medical staff. Here, Irish doctor Gabriel Fitzpatrick describes working for Medecins Sans Frontieres (MSF) at the centre of the outbreak in Sierra Leone:

MSF constructed a special Ebola treatment centre ... Read More

A Friend Turns 95 and Keeps Working in the Lab

Abe Eisenstark is an old friend of both of us. Elio was a graduate student in the Midwest when he first met him. Abe was then a young faculty member at nearby university and was an inspiring mentor to whom Elio gravitated straightaway. The story is a bit different for Stanley, who says: “It is f... Read More

Life Found 800 Meters Down in Antarctic Subglacial Lake

A cold breeze blew off the Antarctic plain, numbing the noses and ears of scientists standing around a dark hole in the ice. Flecks of ice crackled off a winch as it reeled the last few meters of cable out of the hole. Two workers in sterile suits leaned over to grab the payload — a cylinder the... Read More

NIH Scientists Establish New Monkey Model of Severe MERS-CoV Disease (press release)

National Institutes of Health (NIH) scientists have found that Middle East respiratory syndrome coronavirus (MERS-CoV) infection in marmosets closely mimics the severe pneumonia experienced by people infected with MERS-CoV, giving scientists the best animal model yet for testing potential treatm... Read More

What’s the diference between cow TB and human TB?

In 1901, when Robert Koch proposed that the bacilli causing human and bovine tuberculosis were not identical, this view caused much controversy. 113 years later we know that the bovine tuberculosis agent, Mycobacterium bovis, together with other animal strains, forms a separate phylogenetic line... Read More

TWiV 300: So happy together

Recording together for the first time, the TWiV team celebrates their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent  speaks with Dickson, Alan, Rich, and Kathy about their careers in science.


Hosts:  Read More

Synthesis produces new antibiotic

A fortuitous collaboration at Rice University has led to the total synthesis of a recently discovered natural antibiotic.

The laboratory recreation of a fungus-derived antibiotic, viridicatumtoxin B, may someday help bolster the fight against bacteria that evolve resistance to treatments in h... Read More

TWiM 85 Letters

Tom writes:


Hi TWIM, TWIV and TWIP Argonauts,


Your three wonderful podcasts are the nutrient media for growing my scientific knowledge. I have been downloading them from ITunes for a couple of years, and although as a mere amateur I sometimes struggle to keep ... Read More

Experimental Vaccine For Chikungunya Passes First Test

Scientists have taken the first steps to developing a vaccine for chikungunya — an emerging mosquito-borne virus that has infected more than a half million people in the Western Hemisphere this year. About 600 Americans have brought the virus to 43 states.

The study was small. Only 25 people ... Read More

Small Molecule Acts As On-Off Switch for Nature's Antibiotic Factory

Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines.

Their hope now would be to see whether it is possible to manipulate this switch to make nature's anti... Read More

P.aeruginosa fluoresce when exposed to U.V radiation

The Bluish Green Pigment of P.aeruginosa fluoresce when exposed to U.V radiation. Read More

Researchers Link Vaccine Effectiveness to Gut Bacteria

U.S. researchers have found a link between intestinal bacteria and the effectiveness of the flu vaccine. And the finding could have important implications for how vaccines are given.

Our intestines are full of bacteria; they help us digest our food. But scientists are starting to learn how im... Read More

Ebola Could Eventually Afflict Over 20,000, W.H.O. Says

As the tally of deaths from the worst known outbreak of the Ebola virus continued its seemingly inexorable rise, the World Health Organization said on Thursday that the epidemic was still accelerating and could afflict more than 20,000 people — almost seven times the current number of reported c... Read More

The Curious Case of a Protein and a Pilus

If you’re like me, every morning you reluctantly roll out of bed and automatically reach for your toothbrush. One of the earliest learned practices of personal hygiene, brushing surely serves more than just preventing daybreak halitosis — but have you ever pondered about the plaque you try to di... Read More

TWiM 86 Letters

 


Suzanne writes (re Aphids):


The best way to get rid of aphids in the garden (the ants in my yard love to herd them onto my okra) is a sharp stream of water from the hose. Aphids wash right off! They don't tend to come back right away, either.


Read More

Mutating virus suppresses cow’s immune response

Bovine viral diarrhea virus infections result in one of the most costly diseases among cattle with losses in U.S. herds estimated at $2 billion per year, according to professor Christopher Chase of the South Dakota State University Veterinary and Biomedical Sciences Department.

"It is an immu... Read More

Polio: mutated virus breaches vaccine protection

Thanks to effective vaccination, polio is considered nearly eradicated. Each year only a few hundred people are stricken worldwide. However, scientists are reporting alarming findings: a mutated virus that was able to resist the vaccine protection to a considerable extent was found in victims of... Read More

Malaria’s Clinical Symptoms Fade on Repeat Infections Due to Loss of Immune Cells

Children who repeatedly become infected with malaria often experience no clinical symptoms with these subsequent infections, and a team led by UC San Francisco researchers has discovered that this might be due at least in part to a depletion of specific types of immune cells.

Working in Ugand... Read More

MERS: Low transmissibility, dangerous illness

Research led by the University of Bonn Virologists reveals transmission rate of the MERS virus

The MERS coronavirus has caused disease outbreaks across the Arabian Peninsula and spread to Europe several times. The severe pneumonia virus has claimed the lives of several hundred people since it... Read More

Rethinking The Origin of Species: Discover Magazine Features The Speciation Microbiome Project

From Discover: "Scientists have long known of the important roles played by the microbes on and in our bodies — our microbiomes. These little guys outnumber our own cells 10 to 1, and they help regulate everything from the energy we get out of food to the health of our immune systems. Now, scien... Read More
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