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TWiV 399: Zika la femme

The latest Zika virus news from the ConTWiVstadors, including a case of female to male transmission, risk of infection at the 2016 summer Olympics, a DNA vaccine, antibody-dependent enhancement by dengue antibodies, and sites of replication in the placenta.

Hosts:  Read More

TWiP 113: Flying pigs

The TWiP ternion solve the case of the Man from Mexico, and discuss a transgenic toxoplasma vaccine for chickens using Eimeria tenella.

Hosts: Vincent Racaniello Read More

Unusual contaminant morphology

Unknown contaminant seen growing on Brain Heart Infusion (BHI) agar plate after several months at refrigerated temperatures, The organism grew at the edge of the agar plate interface, was smooth and circular, cream/beige mat at the base which mounded up, the edges or center of the colony had fi... Read More

Fungal contaminant on BEA

Fungal contaminant seen on Bile Esculin Agar (BEA) after several months at refrigerated temperatures. The fungus was circular at the edges with mounding in the center and blackening of the media indicating esculin hydrolysis. Read More

Table Top Color

Swab taken from the lab table top and incubated on TSA for 48 hrs, left at room temperature for 72 hrs then held at refrigerated temperature for a month. Pictured is a colorful mucoid orange yeast (possible rhodotorula) slowly overtaking several other colonies (yellow is a presumable yeast as we... Read More

Table top mix

Swab taken from the lab table top and incubated on TSA for 48 hrs, left at room temperature for 72 hrs then held at refrigerated temperature for a month. Pictured is a colorful mix of beige mucoid bacteria, orange and yellow mucoid yeast/bacteria, and white grainy fungi (possible actinomyces?). Read More

Unknown Environmental Swab from Handrail

Out door wood railing was swabbed onto TSA and grown for 48 hrs at 37 degree's C, then allowed to grow at room temperature for 72 hrs the held at refrigerated temperature for a month. This is a close up of some of the organisms that grew. One was a white circular fungal colony with hyphae, the o... Read More

Table Top Swab II

Swab taken from the lab table top and incubated on TSA for 48 hrs, left at room temperature for 72 hrs then held at refrigerated temperature for a month. Pictured is one of the resulting bacterial/fungal growths (yeast): Circular yellow colony, mucoid, with a donut like appearance
Read More

TWiV 398: Permission to be intuitive

Vincent speaks with Sandy Weller about her career and her work on the mechanisms of synthesis, maturation, cleavage and packaging of viral DNA genomes.

Host: Vincent Racaniello 

Guest: ... Read More

TWiM 131: Mice behaving badly

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

Hosts: Vinc... Read More

Disarming a pathogen's ability to cause disease

The anaerobic, Gram-positive Clostridium difficile is a big problem. It causes rampant diarrhea and tissue necrosis, with more than 150,000 annual cases in the United States alone. Many of the disease manifestations of C. difficile are mediated by two exotoxins that C. difficile produces: TcdA a... Read More

What are gut bacteria doing in critically ill lungs? New discovery could change ICU care

No one knows for sure how they got there. But the discovery that bacteria that normally live in the gut can be detected in the lungs of critically ill people and animals could mean a lot for intensive care patients.

Today, scientists are reporting that they found gut bacteria in the deepest r... Read More

Rare fungus product reduces resistance to antibiotics

A team from the Vetmeduni Vienna and the University of Natural Resources and Life Sciences, Vienna succeeded for the first time in extracting the rare compound cPM from a filamentous fungus, applying a special method. Using this substance leads to increased susceptibility of a resistant pathogen... Read More

Gonorrhea May Soon Be Resistant to all Antibiotics

The Centers for Disease Control and Prevention has reported that the wily Neisseria gonorrhoeae bacteria may be developing resistance to the only two antibiotics left that can cure the sexually transmitted disease.
The drugs, azithromycin and ceftriaxone, are used in combination to treat gonorr... Read More

Multi Omics Measurements of Single Samples #mSystems

In systems biology studies, the integration of multiple omics measurements (i.e., genomics, transcriptomics, proteomics, metabolomics, and lipidomics) has been shown to provide a more complete and informative view of biological pathways. Thus, the prospect of extracting different types of molecu... Read More

Genes Found in H. pylori that Influence Biofilm Formation

Washington, DC – July 18, 2016 - Most bacteria cannot survive in the acidic environment of the human stomach, but Helicobacter pylori, a major cause of ulcers, thrives under such circumstances. Now research has shown that one of that bacterium’s regulatory proteins that helps it adapt to these s... Read More

First evidence that GM mosquitoes reduce disease

Releasing genetically modified mosquitoes appears to have helped reduce cases of dengue in a town in Brazil. The news comes as the US is considering whether to approve the use of the same mosquitoes.

The trial involved Aedes mosquitoes that had been modified to kill off wild mosquitoes of the... Read More

Method suitability in microbiology: understanding complex cGMP guidelines

Particularly in the pharmaceutical industry, microbiological method development and, specifically, method suitability is often overlooked or left until the end of a project. However, it is important to give both method suitability and development due consideration as it can be a complicated proc... Read More

Gut bacteria imbalance increases diabetes risk

Currently, scientists think the major contributors to insulin resistance are excess weight and physical inactivity, yet ground-breaking new research by an EU funded European-Chinese team of investigators called MetaHit have discovered that specific imbalances in the gut bacteria can cause insuli... Read More

First known case of female-to-male Zika transmission announced

The first case of female-to-male sexual transmission of the Zika virus has occurred in New York City, the Centers for Disease Control and Prevention announced Friday. Up until now, it was thought that the only likely route of sexual transmission was male-to-female or male-to-male.

The surpris... Read More
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