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TWiP 59: Apicomplexity



Hosts: Vincent Racaniello and Dickson Despommier


Vincent and Dickson update... Read More

TWiP 59 letters

Allan writes:


You have the best podcast on the web, hands down. I use your TWiP episodes in both my undergraduate and graduate classes.
Thanks.


I've recently seen a family in Hawaii with recurrent pathogenic Blastocystis hominis and Dientamoeba fragilis a... Read More

Bad research rising: The 7th Olympiad of research on biomedical publication

What do the editors of medical journals talk about when they get together? So far today, it’s been a fascinating but rather grim mixture of research that can’t be replicated, dodgy authorship, plagiarism and duplicate papers, and the general rottenness of citations as a measure of scientific imp... Read More

Disease-causing genes spread easily in emerging lethal fungus infection

A rare, emerging fungal disease that is spreading throughout Canada and Northwestern USA can easily pass its deadly genes to related fungal strains within the species but less readily to more distant relatives, according to a study part-funded by the Wellcome Trust.

The findings will help to ... Read More

Drug Cocktail That Protects Monkeys From Deadly Virus May Aid Humans

A combination of two well-known antiviral drugs protects monkeys against MERS and could potentially be used to save humans from the lethal disease, scientists said on Sunday.

Researchers at the National Institute of Allergy and Infectious Diseases gave the drugs, ribavirin and interferon, to ... Read More

Bacteria from lean mice prevent obesity in peers

But microbes are only part of the story — the effect also depends on a healthy diet. Gut bacteria from lean mice can invade the guts of obesity-prone cage-mates and help their new hosts to fight weight gain.

Researchers led by Jeffrey Gordon, a biologist at Washington University in St. Louis... Read More

Teaching Pseudomonas to Endocytose

I offer this as an echo to Elio's post from last October, Teaching E. coli to Endocytose. There Elio reported the recent education of E. coli by the heterologous expression of a mammalian gene. I tell of a bacterium instructed by a phage.

Apparently Pseudomonas phage φ6 missed that classic 19... Read More

How many viruses on Earth?

How many different viruses are there on planet Earth? Twenty years ago Stephen Morse suggested that there were about one million viruses of vertebrates (he arrived at this calculation by assuming ~20 different viruses in each of the 50,000 vertebrates on the planet). The results of a new study s... Read More

TWiV 249: An inordinate fondness for viruses



Hosts: Vincent Racaniello, Dickson Despommier,  Read More

BacterioFiles Micro Edition 134 - Duodenum Dweller Degrades Digoxin

This episode: Bacteria in the gut can affect dosaging of medications!




Download Episode (7.1 MB, 7.75 minutes)


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10 Supermarket Health Dangers - MSN Healthy Living

This Week in Microbiology co-host Michael Schmidt is featured on msn.com's Healthy Living in a slideshow about potential health issues at the supermarket:

Placing fresh produce on the checkout belt invites germs to have a field day. Packages of poultry, ground meat, fresh fish and even filet... Read More

Whole Virus HIV Vaccine Excels in Trial

Phase 1 Clinical Trial (SAV CT 01) of the first and only preventative HIV vaccine based on a genetically modified killed whole virus (SAV001-H) has been successfully completed with no adverse effects in all patients, Western and Sumagen Canada Inc. announced.

Click "source" above to read more... Read More

Programmed Cell Death Activates Latent Herpesviruses

Researchers have found that apoptosis, a natural process of programmed cell death, can reactivate latent herpesviruses in the dying cell. The results of their research, which could have broad clinical significance since many cancer chemotherapies cause apoptosis, was published ahead of print in ... Read More

Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses

There have been several outbreaks of highly pathogenic H5N1 avian influenza viruses affecting humans over the past decade, the causes of which have been limited to direct human contact with infected birds. Recent publications suggest that a very small number of coding mutations in the viral HA g... Read More

PRRS Virus Evolution Slows

Porcine reproductive and respiratory syndrome (PRRS) virus remains a very important disease of swine in the United States. At the University of Minnesota Veterinary Diagnostic Laboratory, hundreds of samples are routinely tested for this virus by polymerase chain reaction (PCR) every month. This... Read More

Multiple Mutations Often Needed to Make TB Bacteria Drug-Resistant

Tuberculosis (TB) drug resistance is not an all-or-none phenomenon, according to new research from Rutgers, The State University of New Jersey. Rather, TB-causing bacteria often accumulate mutations in a step-wise fashion, with the initial mutation having minimal impact but poising the bug to la... Read More

Chobani Pulls 'Fizzy,' 'Swelling' Yogurt Off Shelves

NEW YORK -- Chobani is pulling some of its Greek yogurt from supermarket shelves after hearing of "swelling or bloating" in cups.

The company said it has investigated and found a type of mold commonly found in dairy that may be to blame.

Click on "source" above to read more. Read More

TWiM #63: Superantigens, S. aureus, and the armpit microbiome



Hosts: Vincent RacanielloMichael Schmidt and  Read More

TWiM 63 Letters

Hugh writes:


Hi Vincent,


I really enjoyed hearing about Carl Woese in TWiM #50. You mentioned the controversy surrounding of Woese's 1977 discovery of Archea as a third domain of life, as it contradicted entrenched scientific beliefs. Although Archea soon foun... Read More

Victory in the Battle against Brucella: From bench to battlefield

After six years of focused research, Rice-Ficht, director of the Center for Microencapsulation and Drug Delivery at the Texas A&M Health Science Center (TAMHSC), her co-principal investigators and team are nearing completion on the first human Brucella vaccine. Brucella bacteria cause brucellosi... Read More

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