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The first live-attenuated vaccine candidate completely protects against Zika infection

The first live-attenuated Zika vaccine still in the development stage completely protected mice against the virus after a single vaccination dose, according to new research from The University of Texas Medical Branch at Galveston and Instituto Evandro Chagas at the Ministry of Health in Brazil. ... Read More

Anthrax spores use RNA coat to mislead immune system

Researchers from Harvard Medical School have discovered that the body's immune system initially detects the presence of anthrax spores by recognizing RNA molecules that coat the spores' surface. But this prompts an unfavorable immune response that hinders the body's fight against anthrax once th... Read More

Tales of Mystery and Imagination

Over the last ten-plus years of this blog's existence, one cluster of branches on the bacterial phy­lo­ge­ne­tic tree in particular has presented us with fascinating mysteries regarding basic, and seem­ing­ly unique, cellular biology. Many aspects of the species on these branches remain enigmati... Read More

Health Status Disparities and the Microbiome

Bacteria of the microbiome are essential aspects of human health. The best example is in the human gut. Home to nearly three pounds of bacteria (with recent estimates at 3.8·1013 bacteria), our gut uses its microbiome to neutralize toxic byproducts of digestion, stimulate digestion, assist with ... Read More

BEA Fungal Contaminant III

Close up of a white fungal contaminants seen on Bile Esculin agar (BEA) after several month at refrigerated temperature. The BEA agar did turn black indicating esculin hydrolysis. This colony mounded in a cone shape with rhizoid growth towards the top and mat lobate growth around the edges. Read More

TWiV 436: Virology above Cayuga's waters

At Cornell University in Ithaca, New York, Vincent speaks with Susan, Colin, and Gary about the work of their laboratories on parvoviruses, influenza viruses, and coronaviruses that infect dogs, cats, horses and other mammals.


Host:  Read More

BEA contaminant II

Close up of a white fungal contaminants seen on Bile Esculin agar (BEA) after several montha at refrigerated temperature. The BEA agar did turn black indicating esculin hydrolysis. Read More

Maybe they're born with it: intrinsic antibiotic resistance

Several recently published mBio studies describe new mechanisms of intrinsic antibiotic resistance. These mechanisms may themselves become therapeutic targets to broaden the application of currently available drugs. Read More

On an international hunt for new pathogens, team finds novel coronavirus in a Ugandan bat

Simon Anthony has spent his scientific career studying viruses and their impact on health. In the United Kingdom, where he is from, he investigated viruses of agricultural significance. Then, at the San Diego Zoo, he focused on the microbes of wildlife. Currently, at Columbia University’s Mailma... Read More

Zika Update: A Round-up of Recent Reports

Though it's been less covered by major news outlets, Zika is still an important research topic. Scientists are working hard to understand Zika virus biology, transmission, and treatment. We round up the latest research reports on this still-emerging disease. Read More

Shoe Swab Mix II

This was a swab taken form the bottom of a shoe incubated for 48 hrs at 37 degrees C then held at room temp for 48 hrs then held at refrigerated temp's. A variety of colony morphology is seen, rhizoid, mucoid, etc. Image taken using transmitted light. Read More

BEA Fungal Contaminant

Seveal fungal contaminants seen on Bile Esculin agar (BEA) after several montha at refrigerated temperature. The BEA agar did turn black indicating esculin hydrolysis. Read More

Fine Reading: Unearthing the Roots of Ectomycorrhizal Symbioses

This is a primer on the mycorrhizae, the association of plant roots and fungi. An outstanding re­view article on this subject has recently appeared, authored by four Frenchmen and one Ameri­can: F. Martin, A. Kohler, C. Murat, C. Veneault-Fourrey, and D. S. Hibbett. I found reading it both excit... Read More

TWiM #149: You're going to learn R

The TWiM team speaks with Pat Schloss about assigning sequence data to operational taxonomic units, and his experience with mSphere Direct, a new way of submitting papers for publication.

Hosts Vincent ... Read More

TWiV 435: Two virus particles walk into a cell

The TWiVome discuss the blood virome of 8,420 humans, and thoroughly geek out on a paper about the number of parental viruses in a plaque.


Hosts: Vincent Racaniello Read More

Purple Scream

Please submit your best bacterial masterpiece to the American Society for Microbiology's annual Agar Art contest!

Shown here is Vibrio fischeri grown on extra salty LB that was stategically dyed purple with Crystal Violet and accentuated with colored markers. Read More

Embryonated egg of Ascaris lumbricoides.

Embryonated egg of Ascaris lumbricoides. (Larva is motile inside the shell when seen under microscope)
It is infective stage of Ascaris. On ingestion the cortication is dissolved by gastric acid and the larva inside the egg is released. Fertilized eggs freshly passed in stool are non infective.... Read More

How computer scientists are setting the stage to end tuberculosis

One of the conundrums facing TB research is the fact that Mtb grows incredibly slowly. Slow growth confounds both research and treatment since it can take days to weeks to grow a culture for study, a month or more to determine drug resistance properties of a patient sample, and months of antibio... Read More

Bacteria from Russian Church Icons

24 hours of cultivating, blood agar, t' 37 Read More

Bubbles

Pigmented agar, 5 days of cultivating, t' 5 Read More
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