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‘Survival gene’ stops strains of TB mutating into deadly ‘superbugs’

In a joint study, published today (Friday 27 January) in the journal Nature Communications, scientists from the Centro Nacional de Biotecnología in Madrid and the University of Sussex / Brighton and Sussex Medical School in Brighton report the discovery of a gene called NucS that dramatically re... Read More

Kansas State University is the 'Silicon Valley for biodefense,' according to Blue Ribbon Study Panel

What Silicon Valley is to technology, Kansas State University is to biodefense.

When former Senate Majority Leader Tom Daschle and the bipartisan Blue Ribbon Study Panel on Biodefense visited the Manhattan campus on Thursday, Jan. 26, for a series of agrodefense discussions, the university ce... Read More

Un Tour d'Horizon

When biochemists deciphered the genetic code in the 1960s (the triplet 'al­pha­bet' for amino acids whose defined order make up the protein 'words' ) it was – and still is – the most compelling evi­­dence for a common "descent with modifications" (Charles Darwin) of all life on Earth: the al­pha... Read More

BacterioFiles 284 - Remedies Reduce Recipient Rejection

This episode: Modifying mice's microbial communities increased mouse survival before a transplantation was rejected by their immune system!


(9.6 MB, 10.5 minutes)


Show notes: 


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TWiV 426: I'm Axl, and I'll be your cervid today

The sages of TWiV explain how chronic wasting disease of cervids could be caused by spontaneous misfolding of prion protein, and the role of the membrane protein Axl in Zika virus entry into cells.


Hosts:  Read More

Multivalent vaccines may help prevent future outbreaks

The Coalition for Epidemic Preparedness Innovation (CEPI) hopes to prevent future outbreaks by generating, testing, and storing vaccines before outbreaks occur. How do you design a vaccine before a prevailing serotype is determined? Read More

Vacay Vaccinations and The Diseases They Protect You From

It’s winter in the northern hemisphere and many are itching to hit the sun and sand in an exotic location. I, myself, took leave from the cold weather and spent several weeks this January traveling through India. This is the first time I travelled to Asia, and it took slightly more than a few mo... Read More

Kodameae ohmeri

Kodamaea ohmeri grown on SabDex Agar at 30 C. An emerging human pathogen that has been shown to cause fungemia, endocarditis, funguria, and peritonitis in immunocompromised patients. It is resistant to most of the antifungal drugs. Read More

TWiM #144: Did eukaryotes invent anything?

The TWiMers discuss how changes in domestic laundering affect the removal of microorganisms, and assembly of a nucleus-like structure during viral replication in bacteria.


Hosts: Vincent Racaniello, Read More

TWiM 144 Letters

Kayla writes:


Hey there TWIM team


I am a Veterinary Microbiologist in Cork in Ireland!


Long time listener of all the TWIX series and I love everyone of them.


I work in a diagnostic lab in cork and the only thing that gets me through the day is ... Read More

Interlab Reproducibility in Bacterial Genotyping by Whole-Genome Sequencing

One of the most important aspects of a new laboratory protocol is its reproducibility (as previously discussed on ASM’s Microbial Sciences blog). A protocol must produce the same results when performed by different scientists at different labs, and this is especially important when considering n... Read More

We Know You Want To, but You Really Shouldn't Be Kissing Your Pet on the Mouth

If you live with pets, you know where their tongue has been, yet you let them kiss and lick you all they want without even thinking twice about it. I've heard people say that a dog's mouth is very clean, and that their saliva, delivered by licking, can help heal wounds, but is that really true?
... Read More

High protein diet could reduce obesity in dogs

“There are many gut microbiome studies on humans and rodents, but not a whole lot on dogs, in particular,” says Johnny Li, a computational biologist at the Nestle Purina PetCare Company, in St. Louis. He recently led a study on the connection between diet and intestinal bacteria on 64 dogs — 32 ... Read More

Influenza Viruses by James McSharry, PhD

In this ASM Virtual Lecture Dr. James McSharry, Professor Emeritus, Albany Medical College, describes the structure of the influenza viruses, types of human influenza viruses and their replication in cells, licensed influenza drugs, current influenza vaccines, and the future of influenza vacci... Read More

"Molecular Diagnosis of Wound Infection: The Holy Grail?"

Molecular diagnosis is creeping into many areas of bacteriology, but the diagnosis of wound infection remains "stubbornly" culture based. What are the barriers to using molecular methods on wound swabs, and are there any potential solutions?... Read More

Virus communication system discovered

Bacteria can communicate through a system known as quorum sensing, where, for example the production of toxin in some species is not initiated until a minimum threshold of bacterial cells are present. This allows them to coordinate and therefore strengthen their actions to overcome selective pre... Read More

Viruses Overheard Talking to One Another

Viruses may be stealthy invaders, but a study at the Weizmann Institute of Science reveals a new, chatty side of some: For the first time, viruses have been found communicating with one another. This communication – short “posts” left for kin and descendants – helps the viruses reading them to d... Read More

Team discovers how bacteria exploit a chink in the body’s armor

Scientists have discovered how a unique bacterial enzyme can blunt the body’s key weapons in its fight against infection.

Researchers at the University of Illinois at Urbana-Champaign and Newcastle University in the U.K. are investigating how infectious microbes can survive attacks by the bod... Read More

Industrial Microbiology Market Expected to Reach US$ 9.4 Bn in 2016, North America Most Profitable Market Globally

The global industrial microbiology market is expected to witness a y-o-y growth of 6.7% in 2016 over 2015 and reach US$ 9.46 Bn in revenues. North America will continue to be the most lucrative market, accounting for over 25% of the market share.

In addition to increase in food consumption, r... Read More

BacterioFiles 283 - Phages Furnish Photosynthetic Fortifications

This episode: Viruses infecting photosynthetic bacteria could transfer immunity to other viruses between their hosts!


(6.8 MB, 7.4 minutes)


Show notes: 


Read More
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