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Staphylococcus epidermidis Antimicrobial δ-Toxin (Phenol-Soluble Modulin-γ) Cooperates with Host Antimicrobial Peptides to Kill Group A Streptococcus

Antimicrobial peptides play an important role in host defense against pathogens. Recently, phenol-soluble modulins (PSMs) from Staphylococcus epidermidis (S. epidermidis) were shown to interact with lipid membranes, form complexes, and exert antimicrobial activity. Based on the abundance and inn... Read More

Sharing a hospital room increases risk of 'super bugs'

Staying in a multi-bed hospital room dramatically increases the risk of acquiring a serious infectious disease, Queen's University researchers have discovered.

A new study led by infectious diseases expert Dr. Dick Zoutman says the chance of acquiring serious infections like C. difficile (Clo... Read More

Swedish study opens new potential for combating resistant bacteria

Neisseria meningitidis, the meningococcus, is a bacterium that can cause diseases with high fatality rates, and there has therefore been considerable concern that, like other bacteria, it might become resistant to antibiotics. But now a study from örebro University and örebro University Hospital... Read More

Indiana startup raises $444K for bacteria-detection technology

Advanced BioImaging Systems LLC has received a $444,000 investment for technology licensed from Purdue University that uses a laser to detect bacteria in food products.

The company plans to use the private funding to further development of its BARDOT (Bacteria Rapid Detection using Optical Sc... Read More

Prion evolution takes lessons on diversification from viruses

When prions are transferred from one species to another—like from sheep and cows to mice in the laboratory or to humans in the case of the fatally neurodegenerative variant Creutzfeldt-Jakob disease—new forms of the infectious proteins can emerge over time that make them deadly to the new host. ... Read More

Eavesdropping on Bacterial Conversations May Improve Chronic Wound Healing

Listening in on bacterial conversations could be the solution for improving chronic wound care, says a team of researchers at Binghamton University, State University of New York. Their findings have been published in the Journal of Applied Microbiology.

"Bacteria, often viewed as simplistic c... Read More

Scientists Develop Tumor-Busting Bacteria

Scientists have unveiled a new technique that uses fragments of genetically-engineered bacteria to target and destroy tumor cells. Therapies based on this method may treat diseases more efficiently and dramatically reduce side effects by eliminating the need to flood the patient's system with ca... Read More

Single Atom Controls Motility Required for Bacterial Infection

Bacteria can swim, propelling themselves through fluids using a whip-like extension called a flaggella. They can also walk, strolling along solid surfaces using little fibrous legs called pili. It is this motility that enable some pathogenic bacteria to establish the infections -- such as mening... Read More

Blastomyces dermatitidis

Blastomyces dermatitidis on BHI agar. Yeast phase colonies Read More

Scientists Identify Target That May Inhibit HIV Infectivity

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) have discovered a new agent that might inhibit the infectivity of HIV. The agent, surfen, impairs the action of a factor in semen that greatly enhances the viral infection. Surfen might be used to supplement current HIV micr... Read More

Multitasking May Be Achilles Heel for Hepatitis C

Despite its tiny genome, the hepatitis C virus packs a mean punch. The virus is a microcosm of efficiency, and each of its amino acids plays multiple roles in its survival and ability to sidestep attack. But new research from Rockefeller University suggests that this fancy footwork and multitask... Read More

Infectious disease research in US receives new funding

Immunological research focusing on dengue, malaria and tuberculosis will be supported by new grants from the US National Institutes of Health.

The research, to be conducted at the La Jolla Institute for Allergy & Immunology in California, will focus on identifying epitopes – pieces of a v... Read More

Out of the salt mines: Microbial DNA, 419 million years old, with a twist

From a salt mine 1,200 feet beneath the earth's surface, a team led by a West Chester University scientist says it has extracted the oldest known samples of DNA - dated to a staggering 419 million years ago.

The genetic material, belonging to a kind of microbe called haloarchaea (hahlo-ar-KEY... Read More

Too-dilute disinfectant boosts bacteria resistance

Pseudomonas aeruginosa, a bacterium responsible for severe chest infections, can become tolerant to the commonly used mild disinfectant benzalkonium chloride. The bug develops mutations that enable it to expel the disinfectant. Worse still, tolerant strains can also shrug off ciprofloxacin, a fl... Read More

Ear Infections: New Thinking on What to Do

Parents who've ever suspected their youngster had an ear infection might have been inclined to call the doctor, schedule a visit and expect an antibiotics prescription.

That's been the ritual. But no more.

"Until eight or nine years ago, we'd treat each ear infection at diagnosis," said Dr... Read More

The year ahead: science

The year ahead is shaping up to be one long celebration for the world's oldest science academy. The Royal Society formed on a dreary night in London 350 years ago, when the acquisition of scientific knowledge was little more than a hobby for amateurs and polymaths. As part of the celebrations, w... Read More

Big little bug

So what's the big story of 2010 going to be? What's your best bet? Is it the third wave of the H1N1 virus, or the second wave of the financial collapse as a raft of commercial loans paper hits the fiscal rocks? Is it the continued rise of India and China as commercial superpowers, or is this the... Read More

Scientists turn DNA detectives to track spread of hospital superbugs

The genetic fingerprints of germs are to be mapped to open a new front in the battle against hospital superbugs.

Scientists have embarked on an ambitious project to read the complete genetic codes of pathogens taken from hundreds of people, so that DNA can be used to track the spread of infec... Read More

Virus, cancer drug extends life of animal model with aggressive brain tumor

When combined, a virus that targets cancer cells and a commonly used cancer drug have been found to significantly extend the life expectancy and shrink the tumor of rats carrying malignant gliomas, an aggressive brain tumor, say researchers at Baylor College of Medicine and McGill University in ... Read More

U.S. Reaction to Swine Flu: Apt and Lucky

Although it is too early to write the obituary for swine flu, medical experts, already assessing how the first pandemic in 40 years has been handled, have found that while luck played a part, a series of rapid but conservative decisions by federal officials worked out better than many had dared ... Read More
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