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The Basics: How Alkaline Lysis Works

Alkaline lysis was first described by Birnboim and Doly in 1979 (Nucleic Acids Res. 7, 1513-1523) and has, with a few modifications, been the preferred method for plasmid DNA extraction from bacteria ever since. The easiest way to describe how alkaline lysis works is to go through the procedure ... Read More

Mundo de los Microbios - Episodio 50

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A continuacion: Comunicación entre médicos y veterinarios; comportamiento peligroso en el zoo para niños; carne de vaca irradiada; y más allá del test del olfato.


Comunicación en... Read More

GSCID funded by NIAID are accepting applications for sequencing projects....

The Genome Sequencing Centers for Infectious Diseases (GSCID), funded by the National Institute of Allergy and Infectious Diseases (NIAID), are accepting applications for sequencing and genotyping projects. The three NIAID-sponsored Genome Sequencing Centers for Infectious Diseases are accepting... Read More

Good Bacteria Eat Bad Greenhouse Gas

A small rectangular window on the front of the fermenter shows bubbling liquid inside. If it is clear, then that means it is only solution. If it is foggy, then bacteria have been added. Today, the liquid looks milky grey. It fizzes and froths as the correct amount of air and methane is added, ... Read More

Cryptococcus neoformans

Cryptococcus neoformans in solitary nodule. Gridley stain (400X) Read More

Fungi, caterpillars, plants, bacteria: New frontiers in vaccine production

A popular topic at the World Vaccines Congress was cell-based alternatives to egg-based technologies, which was called the next frontier by Dr. Richard Schwartz of NIAID.

In recent years, a number of research projects have revolved around producing vaccines in animals and plants. Arizona Stat... Read More

Hantavirus update 2010 - Americas (19): Chile (LL)

Authorities of the Osorno Base Hospital just confirmed that a man in this [health care] facility died, the 1st fatal victim caused by [a] hantavirus [infection in this locality]. He was a resident of the San Juan de la Costa community and died on 15 Apr [2010] in this hospital. Corresponding sam... Read More

TWiP 8 letters

Christina writes:


Dear Vincent and Dick Just a quick message to say thank you for this informative and fun podcast series, I have enjoyed all three episodes and hope to listen to many more. Jusy the right thing for a former leishmaniac, now teache Read More

TWiP 8: Frog legs and parasite tales

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Dickson reads his story about sparganosis caused by the diphyllobothroid tapeworm Spirometra mansonoides.


Download  Read More

Toxic asphalt sludge is home to hardy microbes

LIQUID asphalt is not a likely home, but hardy microbes have been found thriving in a natural lake made of the stuff. The discovery hints that alien life could exist in similar places.

Microbes are known to exist in tar pits, but it was not known if natural asphalt pools, with their more toxi... Read More

Simplifying Complexity – New Insights Into How Genomes Work

A genome is a complex system of genes and factors that regulate them. A European research team has clarified how such dynamic systems work, leading to a new way to predict genetic regulators.

As an organism develops and interacts with its environment, suites of genes are constantly being turn... Read More

New book urges reversal of DDT ban to fight malaria

Six years after the insect killer DDT was globally outlawed on grounds of environmental damage, two researchers say there are new reasons for doubting the chemical is harmful and are urging its use against malaria.

In a book launched on Wednesday, Donald Roberts, professor of tropical medicin... Read More

Standardized Testing Method for Cranberry Products Will Reveal Effectiveness of UTI Treatments

Natural compounds in cranberries are linked to the prevention of urinary tract infections (UTIs) but inconsistencies in methods currently used commercially to measure levels can result in the over- or under-estimation of potency levels, leaving product manufacturers and consumers without good da... Read More

U of Chicago Teams with Field Museum on Emerging Pathogen Study

The University of Chicago’s Institute for Genomics and Systems Biology will partner with the Field Museum to study the evolution of species-switching parasites and pathogens that cause diseases such as bird flu, malaria, and AIDS.

The partnership, called the Emerging Pathogens Project, will i... Read More

Listeria Bacteria Shut Down Cellular Response to Stress

Some bacteria take over cells by interfering with an important process called SUMOylation, which helps cells respond to stress. The bacteria release toxins that reprogram proteins inside cells, which prevents the cells from fighting their invaders, HHMI international research scholar Pascale Co... Read More

BacterioFiles Episode 10

In this show, I report on four exciting stories: bacteria for digesting sushi; a giant virus that replicates itself, with help; microbes living in Mars-like lakes; and using viruses to generate hydrogen.




























(12... Read More

Self-starter: Life got going all on its own

In the beginning there were Ida and Luca. The initial Darwinian ancestor - Ida - and the last universal common ancestor - Luca - assembled themselves from the spare parts sloshing around on the early Earth. Once all the ingredients were in place, it looks like life was all but inevitable.

The... Read More

Pulmonary cryptococcus neoformans

Pulmonary coyptococcus neoformans in man, H & E stain Read More

Hops Helps Reduce Ammonia Produced by Cattle

An Agricultural Research Service (ARS ) scientist may have found a way to cut the amount of ammonia produced by cattle. To do it, he's using a key ingredient of the brewer's art: hops.

Cattle, deer, sheep, goats and other ruminant animals depend on a slew of naturally occurring bacteria to ai... Read More

MTS48 - Keith Klugman - Pneumonia: The Hidden Giant

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