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Difference in Gene Numbers Responsible for Wide Variations in the Human Genome

When scientists announced in 2003 that they had finished the Human Genome Project, they were quick to clarify that sequencing of the full human genome not yet complete. As much as six percent of the genome was beyond the reach of available technology, leaving regions on the 23 pairs of human chr... Read More

MicrobeWorld at the 2010 USA Science and Engineering Festival

This past weekend the USA Science and Engineering Festival came to Washington, D.C. The American Society for Microbiology and MicrobeWorld were present with our own booth in which we offered several microbe-related activities for attendees of all ages.

In this picture, Barbara Hyde, director... Read More

Haptoglobin as an early serum biomarker of virus-induced type 1 diabetes in rats

Type 1 diabetes (T1D), formerly known as juvenile diabetes, is a multifactorial disease of complex etiology characterized by the autoimmune destruction of pancreatic beta cells. In addition to genetic susceptibility, it is generally accepted that environmental factors play important roles in tri... Read More

What does HIV sound like?

There is no question that HIV is an ugly virus in terms of human health. Each year, it infects some 2.7 million additional people and leads to some 2 million deaths from AIDS. But a new album manages to locate some sonic beauty deep in its genome. Sounds of HIV (Azica Records) by composer Alexan... Read More

Sepsis can lead to mental, physical decline: study

Older adults who develop sepsis ā€” a serious, widespread bacterial infection -- are at risk of declining both mentally and physically in subsequent years, a new study has found.

The researchers say their findings suggest the long-term effects of sepsis are under-recognized and could account fo... Read More

Panel: Teens need another meningitis shot

A federal advisory panel is recommending that teens get a booster dose of the vaccine against bacterial meningitis.

They made the recommendation because the vaccine doesn't work as long as expected.

Three years ago, the Advisory Committee on Immunization Practices said the meningitis vacci... Read More

Groups moving forward to develop AIDS gel

Groups developing a gel to protect women from the AIDS virus say they are moving ahead to develop the product that was hailed as "groundbreaking" after a study on its effectiveness was released in July.

The developers, who met last week with the U.S. Food and Drug Administration, said the FDA... Read More

Scientists Helping Keep in-Demand Smoked Salmon Safe to Eat, Thanks to New Mathematical Model

Scientists with the U.S. Department of Agriculture (USDA) are helping ensure that the smoked salmon that's always a hit at festive gatherings also is always safe to eat, including among their achievements the development of a first-of-its-kind mathematical model that food processors and others c... Read More

Superbug infection in Brazil hospitals kills 18

Eighteen people have died in the Brazilian capital after contracting a hospital superbug.

They were infected with bacteria which produce the enzyme Klebsiella pneumoniae Carbapenemase (KPC), which renders most modern antibiotics ineffective.

It tends to infect hospitalised people whose imm... Read More

Alemtuzumab Raises CMV Infection Risk

Cytomegalovirus (CMV) infection in kidney or kidney/pancreas transplant recipients occurs more frequently when alemtuzumab is used for induction instead of antithymocyte globulin (ATG), according to a new study from the University of Minnesota in Minneapolis.

In addition, in alemtuzumab recip... Read More

Africa to launch mass polio vaccination campaign

The World Health Organization on Tuesday announced a mass polio vaccination campaign in Africa, the same day Ugandan health officials announced an outbreak of the highly infectious disease.

WHO officials in Geneva said the 15-country campaign would start as early as next week in Angola and Co... Read More

Haiti capital braced for cholera

While the cholera outbreak that has so far killed 259 in Haiti is starting to taper off, the capital Port-au-Prince is bracing itself for the disease's arrival. Can treatment reach people in time to prevent more deaths?

Emergency supplies of clean water, soap and water-purifying equipment con... Read More

Proteins get the glory, but are non-protein-coding RNAs doing the work?

When it comes to biology, the proteins get all the glory. A new study coming out in mBio might change this, though: the results show that, in the immune response, non-protein-coding RNAs may deserve some credit for what they do, too.
Peng et al. used whole transcriptome analysis in mice to e... Read More

Journal of Bacteriology authors have sequenced 13 different strains of Borrelia burgdorferi, the bacteria that cause Lyme disease, the most common tickborne disease in North America.

Press release from National Institute of Allergy and Infectious Diseases (NIAID) on the significance a Genome Announcement by Steven E. Schutzer, Claire M. Fraser-Liggett, Sherwood R. Casjens, Wei-Gang Qiu, John J. Dunn, Emmanuel F. Mongodin, and Benjamin J. Luft published ahead of print in the... Read More

Respiratory virus infection triggers new class of biomolecules

For the first time, scientists have discovered that a poorly understood class of RNA produced in a mammal's cells during a respiratory virus attack may affect the outcome of the infection. Their findings are reported today in mBio, a journal of the American Society for Microbiology.

RNA (ribo... Read More

New Strategy to Kill Bugs -- Even Those in Hiding

New strategies to apply antibiotics more effectively to hibernating bugs have been developed by researchers at the University of Hertfordshire.

In a paper, which appeared this month in the Institute of Electrical and Electronics Engineers (IEEE) Transactions on Evolutionary Computing, Dr Ole ... Read More

Listeria 'tricks' cells to infect humans

Listeria bacteria, a source of food-borne illness, tricks cells in the body's intestines to pass through those cells and make people sick, researchers say.

Researchers at Purdue University found that listeria, even in low doses, somehow triggers intestinal cells to express a protein that acts... Read More

China reports first cases of NDM-1 super bacteria infection

China's health authorities Tuesday announced the country's first three cases of NDM-1, a multi-drug resistant super bacteria.

Chinese Center for Disease Control and Prevention (China CDC) official Ni Daxin said at a press conference that two cases were detected from samples submitted by the l... Read More

Frog prince sensor fights bacteria

A newly developed sensor may revolutionize how drugs and medical devices are tested for contamination.

In the process it may also help ensure the survival of two species of threatened animals. To be fair, some of the credit goes to an African frog.

In the wild, the African clawed frog pro... Read More

TWiP 18: Cryptosporidium

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Vincent and Dickson discuss the intracellular parasite Cryptosporidium, which causes diarrheal disease in most mammalian species.

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