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Learning to tolerate our microbial self

The human gut is filled with 100 trillion symbiotic bacteria—ten times more microbial cells than our own cells—representing close to one thousand different species. "And yet, if you were to eat a piece of chicken with just a few Salmonella, your immune system would mount a potent inflammatory re... Read More

Bacteria interrupted: Disabling coordinated behavior and virulence gene expression

New research reveals a strategy for disrupting the ability of bacteria to communicate and coordinate the expression of virulence factors. The study, published by Cell Press in the April 22nd issue of the journal Molecular Cell, may lead to the development of new antibacterial therapeutics.

B... Read More

Salmonella utilize multiple modes of infection

Scientists from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany have discovered a new, hitherto unknown mechanism of Salmonella invasion into gut cells: In this entry mode, the bacteria exploit the muscle power of cells to be pulled into the host cell cytoplasm. Thus, ... Read More

FDA Warns 4 Companies Over Drug-Resistant Bacteria Claims

The U.S. Food and Drug Administration issued four warning letters to companies selling over-the-counter products that claim to prevent methicillin-resistant Staphylococcus aureus bacteria, or MRSA, infections. The companies that received FDA warnings are Tec Laboratories, JD Nelson and Associat... Read More

How TRIM5 Fights HIV: Scientists Discover Mechanism of Protein That Makes Certain Monkeys Resistant

Thanks to a certain protein, certain monkeys are resistant to HIV. Known as TRIM5, the protein prevents the HI virus from multiplying once it has entered the cell. Researchers from the universities of Geneva and Zurich have now discovered the protein's mechanism, as they report in Nature. This a... Read More

Acinetobacter baumannii

This SEM depicts a couple of clusters of aerobic Gram-negative, non-motile Acinetobacter baumannii bacteria as seen under a magnification of 12,739x.

Members of the genus Acinetobacter are nonmotile rods, 1-1.5µm in diameter, and 1.5-2.5µm in length, becoming spherical in shape while in their... Read More

Emerging Diseases - The Importance of Early Warning and Surveillance Systems (MWV48)

In episode 48 of MicrobeWorld Video, filmed at the American Association for the Advancement of Science Meeting in Washington, D.C., on February 18, 2011, Dr. Stan Maloy talks with Read More

Stomach damage by H. pylori under partial control of Mua protein

Helicobacter pylori’s own heartburn remedy may be a good means for preventing the damage the stomach-ulcer pathogen causes. H. pylori lives happily in the stomachs of about half of the world’s population, where it relies heavily on the enzyme urease to break down urea in stomach acid into carbon... Read More

Human Immunodeficiency Virus (HIV-1)

This scanning electron micrograph revealed the presence of the human immunodeficiency virus (HIV-1), (spherical in appearance), which had been co-cultivated with human lymphocytes. Note the lymphocyte in the lower left, and some of its extended pseudopodia. HIV-1 virions can be seen on the surfa... Read More

Adaptive Trial Designs Could Accelerate HIV Vaccine Development

In the past 12 years, four large-scale efficacy trials of HIV vaccines have been conducted in various populations. Results from the most recent trial—the RV144 trial in Thailand, which found a 31 percent reduction in the rate of HIV acquisition among vaccinated heterosexual men and women—have ... Read More

EPO doping helps combat cerebral malaria

Almost 3.3 billion people, half of the world's population, risk being infected with malaria. Despite having effective means against malaria, the WHO reports 250 million cases of malaria each year and more than 700,000 related deaths. Researchers at the University of Copenhagen have now discovere... Read More

Solutions for 'culture crashes' in algal production sought

Algae can seem quite stubborn and hardy when trying to rid them from your pool, but when it comes to mass producing algal feedstock to be used in the conversion to biofuel, more things can happen to destroy this type of crop than most realize.

Of many culprit organisms that may result in the... Read More

Study hints at probiotics as treatment for Clostridium difficile

Asymptomatic colonization by Clostridium difficile, absent the use of antibiotics, is common in infants and when it happens changes occur in the composition of the gut microbiota according to research published in the March 2011 issue of the Journal of Clinical Microbiology.

The adult human ... Read More

TWiM #5: Mercury-methylating Desulfovibrio and antimicrobial nanoparticles

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.


Hosts: Vincent Racaniello, Cliff Mintz, Read More

TWiM 5 Letters

Stephen writes:


Vincent, TWIV, TWIP amd TWIM are wonderful for a retired person like myself.  I worked in IT, but started out with a biology undergrad that instilled my interest in biology many years ago. I always look forward to the next podcast. I have discov... Read More

Gigantic New SuperOrganism with 'Social Intelligence' is Devouring the Titanic

"In 2000, Roy Cullimore, a microbial ecologist and Charles Pellegrino, scientist and author of Ghosts of the Titanic discovered that the Titanic --which sank in the Atlantic Ocean 97 years ago -- was being devoured by a monster microbial industrial complex of extremophiles as alien we might expe... Read More

Gut Bacteria Divide People Into 3 Types, Scientists Say

In the early 1900s, scientists discovered that each person belonged to one of four blood types. Now they have discovered a new way to classify humanity: by bacteria. Each human being is host to thousands of different species of microbes. Yet a group of scientists now report just three distinct e... Read More

Astrobiologists Discover Strange Benthic Microbial Mats in Antarctica

Photosynthetic microbial mats forming large conical structures up to half a meter tall have been discovered by astrobiologists in Lake Untersee, Antarctica. This research is described in an article in the May 2011 issue of the journal Geobiology.

Lake Untersee is located at 71°20'S, 13°45'E i... Read More

Phomopsis Mold

Cultures of a destructive mold called Phomopsis strains that infect both crop and noncrop plants. One of the species of this genus, Phomopsis viticola, cause a plant disease called phomopsis or dead-arm. Usually, infections begin during early growth stages in spring. This affects leaves, fruit, ... Read More

Parents' Vaccine Safety Concerns Dominate Office Visits

Primary care physicians report that the time it takes to allay parental fears about childhood vaccines makes it difficult to accommodate these conversations in a typical office visit.

A new study published online April 15 in the American Journal of Preventive Medicine shows that 53% of family... Read More
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