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TWiM #120: Snakes in trouble

Hosts: Vincent Racaniello and Elio Schaechter.


Vincent and Elio marvel in the finding that a phage tail-like struc... Read More

Zika virus

The rapid spread of Zika virus through the Americas, together with the association of infection with microcephaly and Guillain-Barré syndrome, have propelled this previously ignored virus into the limelight. What is this virus and where did it come from?
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Resistance to key HIV drug 'concerningly common'

HIV drug resistance to tenofovir, an antiretroviral drug vital to most modern HIV treatment and prevention strategies, is surprisingly and worryingly common according to a large study led by UCL (University College London) and funded by the Wellcome Trust. Read More

TWiV 374: Discordance in B

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

A chromosome in every cell: PprA funcitons in chromosome segregation after Deinococcus radiodurans irradiation

Exposure to reactive oxygen species, exposure to ionizing radiation, exposure to UV light – all of these are dangerous because of their potential to alter DNA sequences. Changes in DNA can affect a protein coding sequence, potentially influencing its function, but changes in regulatory regions c... Read More

HITTING INFECTIONS HARD CAN BE ‘THE WORST THING TO DO’

The standard practice of treating infections with the highest tolerable dose of antibiotic medications may not always be best way of preventing the evolution of drug resistance, a new study suggests. Read More

Defining the rate-limiting processes of bacterial cytokinesis

This paper addresses some fundamental unanswered questions in microbiology: is the cytoskeletal cell division ring a major driving force for bacterial cytokinesis as it is for eukaryotes? If so, what is the mechanism? If not, what process is the major driving force?

One key technique that we ... Read More

Flu tackles Super Bowl fans

ITHACA, N.Y. - If you're a fan of the Panthers or Broncos, be sure to wash your hands on Super Bowl Sunday before you give a friend a celebratory fist bump.

A Cornell University economist and his colleagues have found the geographical areas that have an NFL team advance to the Super Bowl had ... Read More

MMP #9: Customizing phage by swapping tail genes to target specific pathogens

Host: Jeff Fox with special guest, Timothy Lu.


Lu, an Associate Professor of Biological Engineering and Electrical Engineering and Computer Science at Massachusetts Institute of Technology in Cambridge, Massachuse... Read More

Skin infections rife among high school wrestlers, say CU Anschutz researchers

DENVER (Feb. 3, 2016) - The first national survey of skin infections among high school athletes has found that wrestlers have the highest number of infections, with football players coming in a distant second, according to researchers at the University of Colorado Anschutz Medical Campus. Read More

Flu vaccine shows promise for reducing risk of influenza-associated atrial fibrillation

Philadelphia, PA, February 2, 2016 - Influenza is significantly associated with an increased risk of new-onset atrial fibrillation, which could be reduced through influenza vaccination, according to new findings reported HeartRhythm. Read More

2 THINGS WE NEED TO FIGHT ZIKA’S EXPLOSIVE SPREAD

A recent outbreak of Zika virus in Brazil is causing alarm throughout the Americas, with health officials warning that the disease is “spreading explosively.” The World Health Organization (WHO) held an emergency meeting to address the problem, and the Centers for Disease Control and Prevention ... Read More

Bacterial Symbiosis?

Some kids & I have been swabbing their classroom, and this colony caught my eye, or is it two colonies living in a mutualistic relationship. Perhaps this is commensalism as the red one seems to really like the yellow one. Or perhaps it is the same colony of microbes, somehow producing two differ... Read More

Zika from sex, the byway but not the highway

Can Zika virus be sexually transmitted? Perhaps in very rare cases, but the main mode of transmission is certainly via mosquitoes. That’s why I’ve shamelessly stolen a quote on this topic from Dr. William Schaffner of Vanderbilt University: Mosquito transmission is the highway, whereas sexual tr... Read More

Adenosine deaminase may help the immune system fight HIV on its own

New research findings published in the February 2016 issue of the Journal of Leukocyte Biology, suggest that a new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug. The drug, an enzyme called adenosine deaminase, or ADA, ultimately may be able to... Read More

Alcaligenes faecalis line inoculation with swarming

A line inoculation was done with Alcaligenes faecalis and incubated for 48 hrs at 37 degree's C. Swarming/spreading could be seen form the inoculation line. Note: Small contaminate also seen on the plate.
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First reported autopsy of patient with MERS coronavirus infection provides critical insights

Philadelphia, PA, February 5, 2016 - Since 2012, at least 1,500 individuals have developed Middle East respiratory syndrome (MERS), resulting in more than 500 fatalities. Only now are results being reported of the first autopsy of a MERS patient, which was performed in 2014. Not only do these fi... Read More

E. coli, Salmonella, and Norovirus - oh my!

This upcoming Monday, Chipotle restaurants across the country will close as its employees discuss food safety and safe food handling. The restaurant was in the news throughout the last half of 2015, beginning with an outbreak of E. coli in Seattle (which was kept secret!), followed by another E.... Read More

Study reveals how herpes virus tricks the immune system

With over half the U.S. population infected, most people are familiar with the pesky cold sore outbreaks caused by the herpes virus. The virus outsmarts the immune system by interfering with the process that normally allows immune cells to recognize and destroy foreign invaders. How exactly the ... Read More

The dual role of GALNT3 during influenza infection

Feeling under the weather? Are you congested, maybe having a hard time breathing, especially at night? Don’t worry – this is your body’s natural response to an infection. Mucus production is generally regarded as antimicrobial – it traps particles like virions before they can infect nearby host ... Read More
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