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Discovery aims to fight destructive bee disease

Researchers hope their new discovery will help combat a disease killing honeybee populations around the world. The researchers have found a toxin released by the pathogen that causes American foulbrood disease -- Paenibacillus larvae -- and developed a lead-based inhibitor against it.

Click "... Read More

NIH Allows Restart Of MERS Research That Had Been Questioned

Some researchers who study the virus that causes Middle East respiratory syndrome got an early Christmas present: permission to resume experiments that the federal government abruptly halted in October.

The scientists were trying to modify the MERS virus so that it's better able to sicken mic... Read More

Worries About Unusual Botulinum Toxin Prove Unfounded

Remember that worrisome new form of botulinum toxin we told you about in late 2013, the one that supposedly had to be kept secret out of fear it could be used as a bioweapon that would evade all of our medical defenses?

Well, as it turns out, it's not that scary after all. The antitoxin store... Read More

Fungal Freeways

Just as humans utilize roads and freeways to move cars and resources around our cities, fungus use fluid networks to move nutrients and nuclei through their cells. Dr. Marcus Roper of UCLA explains how these networks function with remarkable efficiency and prevent microscopic traffic jams.

C... Read More

BacterioFiles 196 - Flagellin Facilitates Flu-shot Function

This episode: Bacteria are important for a good immune response to unadjuvanted influenza vaccines!


(14.6 MB, 16 minutes)


Show notes: 
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Discovery in the fight against antibiotic-resistant bacteria

For four years, researchers at Universite catholique de Louvain have been trying to find out how bacteria can withstand antibiotics, so as to be able to attack them more effectively. These researchers now understand how one defense mechanism works and the results of their research have been publ... Read More

SLU Research Finds Enzyme Inhibitors Suppress Herpes Simplex Virus Replication

Saint Louis University research findings published in the December issue of Antimicrobial Agents and Chemotherapy report a family of molecules known as nucleotidyltransferase superfamily (NTS) enzyme inhibitors are promising candidates for new herpes virus treatments.

The findings could lead ... Read More

Life would go on if all bacteria disappeared

Microbes: They're everywhere, including inside our bodies. But are they really necessary? Not to life, scientists argue in a new paper — but certainly to life as we know it.

For starters, microbiologists Jack Gilbert and Josh Neufeld had to put aside the internal cell structures that were pro... Read More

When Threatened By Worms, Bacteria Summon Killer Fungi

When you’re the size of a human, you worry about lions and tigers and bears. But if you’re a bacterium, a tiny nematode worm, just a millimetre long, can be a vicious predator. Nematodes are among the most common animals on the planet, and many of them hunt bacteria in soil and water. The microb... Read More

The debilitating outbreak sweeping the Americas

Its name means "bending over in pain." It has no treatment or vaccine. Its symptoms resemble Dengue fever. And it has infected more than 1 million people -- 155 of them fatally -- since spreading to the Americas one year ago.

The mosquito-borne Chikungunya virus has long been diagnosed in tra... Read More

Oncolytic viruses as anticancer vaccines

Oncolytic virotherapy has shown impressive results in preclinical studies and first promising therapeutic outcomes in clinical trials as well. Since viruses are known for a long time as excellent vaccination agents, oncolytic viruses are now designed as novel anticancer agents combining the aspe... Read More

Bacterial Motors Come in a Dizzying Array of Models

Bacteria that can swim propel themselves with corkscrew tails anchored in rotary motors. That may seem surprisingly mechanical for a microbe, but it is a system that has been wildly popular and conserved across billions of years of evolution.

To see what I mean, I encourage you to visit this ... Read More

New study offers novel insights into pathogen behavior

A new study by a team of researchers that includes University of Notre Dame scientists Joshua Shrout and Mark Alber provides new insights into the behavior of an important bacterial pathogen.

Alber, Vincent J. Duncan Family Professor of Applied Mathematics, and Schrout, an associate professor... Read More

First successful vaccination against 'mad cow'-like wasting disease in deer

Researchers say that a vaccination they have developed to fight a brain-based, wasting syndrome among deer and other animals may hold promise on two additional fronts: protecting US livestock from contracting the disease, and preventing similar brain infections in humans. Read More

Infectious disease: Mobilizing Ebola survivors to curb the epidemic

Multiple governments and non-governmental organizations have called on health-care personnel the world over to help control West Africa's Ebola outbreak; these include Médecins Sans Frontières (MSF), the World Health Organization (WHO) and United Nations children's charity UNICEF. But the demand... Read More

How llamas' unusual antibodies might help in the fight against HIV/AIDS

Most vaccines work by inducing an immune response characterized by neutralizing antibodies against the respective pathogen. An effective HIV vaccine has remained elusive so far, but researchers have continued to make progress, often employing innovative methods. A new study reports that a combin... Read More

One Common Genetic Variant and the Bacteria Inside Of Us Help Dictate Inflammation, Antitumor Activity, and Outcome in Cancer Patients

A common polymorphism – a variation in a person’s DNA sequence that is found with regularity in the general population – can lead to a chain of events that dictates how a tumor will progress in certain types of cancer, including a form of breast cancer as well as ovarian cancer, according to new... Read More

The Race to Create Ebola Treatments From Survivors’ Blood

Scientists waging war against Ebola are mining a cache of microscopic weapons hidden in Ebola survivors’ blood.

Made by the immune system, the weapons are antibodies, small proteins that target and neutralize invading virus particles. Scientists aren’t sure about the molecular specifics yet, ... Read More

S.aureus hemolysis on blood agar

I took these combined pictures after growing S. aureus ST151 and ST3028 on blood agar plates. Both strains were isolated from cases of subclinical mastitis The plates were incubated at 37 C for 24 or 48 hrs as shown in the picture. ST3028 is one of the novel strains recently identified in ou... Read More
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