A protein in Salmonella inactivates mast cells -- critical players in the body’s fight against bacteria and other pathogens -- rendering them unable to protect against bacterial spread in the body, according to researchers at Duke Medicine and Duke-National University of Singapore (Duke-NUS).
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Bacteria can evolve rapidly to adapt to environmental change. When the "environment" is the immune response of an infected host, this evolution can turn harmless bacteria into life-threatening pathogens. A study published on December 12 in PLOS Pathogens provides insight into how this happens.
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Looks like Harvard University scientists have given us another reason to walk past the cheese platter at holiday parties and reach for the carrot sticks instead: Your gut bacteria will thank you.
Switching to a diet packed with meat and cheese — and very few carbohydrates — alters the trillio... Read More
A boy with cystic fibrosis develops a chronic and potentially deadly Burkholderia dolosa infection in his lungs. Varieties of genetic mutations allow some strains of the bacteria to survive the dual assaults from his immune system and antibiotics, while others perish. Eventually, the strongest m... Read More
Otherwise innocuous bacteria can cause deadly infections when people have surgery or fall ill. To prevent trouble, patients sometimes have their bodies scrubbed clean of Staphylococcus aureus. But it doesn't always work.
That may because the germs thrive in upper recesses of the nose, far fro... Read More
New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.
In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More
Getting the message out to the public that the microbial world is about much more than just diseases is a challenging topic, but one we should keep trying to improve on. There are many ways to do this, but as the saying goes, a picture is worth a thousand words, and most people don’t want to rea... Read More
The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.
Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More
Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More
It is universally accepted that the use of antibiotics will lead to antimicrobial resistance. Traditionally, the explanation to this phenomenon was random mutation and horizontal gene transfer and amplification by selective pressure. Subsequently, a second mechanism of antibiotic-induced antimic... Read More
"Clinically Important Drug-Resistant Bacteria” Read More
Antibiotic resistance mechanisms of clinically important bacteria. Read More
Genomes provide clues for treating leukemia, endometrial cancers
The phrase "Twitter feed" is about to take on a troubling hue. The Food Standards Authority would like all British citizens... to keep it up to date with the color of their vomit and much more.
The government wants to keep abreast of the norovirus. This virus -- known in the UK as the winter ... Read More
Inactivation of antibiotics and the dissemination of resistance genes Read More
is this increasing resistance of microorganisms ? Read More
Darwin and the 20th century pioneers of biology would have been astonished to see the countless roles that microbes play in shaping eukaryotic life. From the origins of eukaryotic cells to pharmaceutical products, Life as we know it would be unrecognizable without microbes. Integrating microbes ... Read More
Seafloor-dwelling bacteria may hitch a ride on methane bubbles seeping from deep-sea vents, preventing the methane from reaching the atmosphere by eating it up, new research suggests.
The findings, presented here today (Dec. 9) at the annual meeting of the American Geophysical Union, could he... Read More
Blood clots play an unexpected role in protecting the body from the deadly effects of bacteria by absorbing bacterial toxins, researchers at the University of California, Davis, have found. The research was published Dec. 2 in the journal PLoS ONE.
"It's a significant addition to the short li... Read More
Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with “big gun” antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin, according to a Vanderbilt stud... Read More