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Research may yield new ways to treat antibiotic-resistant TB

Scientists in the United States and India have successfully modified the precursor to one of the drugs used to treat tuberculosis, an important first step toward new drugs that can transcend antibiotic resistance issues that experts consider a serious threat to global health.

The findings, re... Read More

Fighting parasitic infection inadvertently unleashes dormant virus

Signals from the immune system that help repel a common parasite inadvertently can cause a dormant viral infection to become active again, a new study shows.

Further research is necessary to understand the clinical significance of the finding, but researchers at Washington University School o... Read More

How deadly lassa virus infects cells

The Lassa virus, endemic to West Africa, uses an unexpected two-step process to enter cells, research has shown. The results suggest that the mechanism by which Lassa virus causes infection is more complicated than previously known, and could lead to new approaches for preventing the disease.

... Read More

Microbe, Enzyme or Mineral? A Riddle in the Soil

When most people look at soil, they just see dirt. When I look at soil, I see billions of microorganisms crawling atop one another, consuming the dead in a feasting frenzy that stops for nothing save a deep freeze. I see microbes and their enzymes, the digestive juices that break down, transform... Read More

microbes style

A microorganism (from the Greek: μικρός, mikros, "small" and ὀργανισμός, organismós, "organism") is a microscopic organism, which may be a single cell or multicellular organism. The study of microorganisms is called microbiology, a subject that began with Antonie van Leeuwenhoek's discovery of m... Read More

microbes to microorganisms

Microorganisms are very diverse and include all the bacteria and archaea and almost all the protozoa. They also include some members of the fungi, algae, and animals such as rotifers. Many macro animals and plants have juvenile stages which are also microorganisms. Some microbiologists also clas... Read More

microbes style

microbes which may be a single cell or multicellular organism. The study of microbes is called microbiology, a subject that began with Antonie van Leeuwenhoek's discovery of microorganisms in 1675, using a microscope of his own design. Read More

TWiV 291: Ft. Collins abuzz with virologists

Vincent, Rich, and Kathy and their guests Clodagh and Ron recorded this episode at the 33rd annual meeting of the American Society for Virology at Colorado State University in Ft. Collins, Colorado.


Hosts: ... Read More

TWiM #81: Cold iron is the master of them all

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 81 Letters

Ravi writes:


TWiM & TWiV team,
Keep up the excellent work! I am an electronics engineer who has never studied biological sciences, but now in my 50's, I find your podcasts fascinating. I listen to episodes while working out - a good combination of mental &... Read More

Streptococcus pyogenes Gram Stain

Gram stain done on S. pyogenes showing the characteristic long G+ streptococcus chains. Culture grown on blood agar for 48 hrs at 37 degree’s C. Read More

Mycobacterium smegmatis Acid Fast Stain

Acid Fast stain done on a mix of Staphylococcus aureus and Mycobacterium smegmatis. Carbol fuchsin was applied to the smear and set over a steaming water bath for 10 min to help penetrate the mycolic acid in the cell wall, then rinsed with acid alcohol which washes the carbol fuchsin out of al... Read More

Slaying bacteria with their own weapons

A chemist at Washington University in St. Louis is studying siderophores, iron chelating molecules released by bacteria during an infection, with the thought of using them to design personalized antibiotic therapy that would avoid the rapid evolution of resistance that plagues antibiotic drug di... Read More

Endospore Stain Bacillus cereus

B. cereus was grown on urea agar for 6 days at 37 degrees C to induce spore formation.
The endospore stain was done using malachite green as the primary stain and safranin as counter the stain. Malachite green was applied to the smear and set over a steaming water bath for 10 min (stain was no... Read More

Love in the lab: Close collaborators

Romance often sparks between colleagues, and scientists are no different. Nature profiles four super-couples who have combined love and the lab.

When physicists Claudia Felser and Stuart Parkin were introduced at a conference on applied magnetics, they felt an immediate attraction. But then, ... Read More

Soil microbiomes can set plant flowering time

Scientists grew Boechera stricta plants in soil inoculated with microbes from natural B. stricta habitats to study the flowering time phenotype.

The technique researchers employed to isolate soil microbes to study their effect on a single plant phenotype can potentially be applied to other st... Read More

Lab-on-a-Chip Tracks Down 'Most Wanted' Microbe

A diagnostic tool that’s about the size of a credit card has identified a highly prized gut microbe.

The microbe contains interesting genetic sequences, but it has proven challenging to culture in the lab.

Researchers used the device, called SlipChip, to isolate microbes from a patient’s g... Read More

The truth behind the '5-Second Rule': When in doubt, throw it out

The burger patty that slides off the plate, the ice cream treat that plops on the picnic table, the hot dog that rolls off the grill – conventional wisdom has it that you have five seconds to pick it up before it is contaminated.

Fact or folklore?

“A dropped item is immediately contaminate... Read More

Sweet Sweet Straw

The calorie free sweetener erythritol is widely used in Asia; it is also gaining popularity in Europe and America. At the Vienna University of Technology, a new cheap method has been developed to produce erythritol from straw with the help of mould fungi.

Erythritol has many great advantages:... Read More

Virus kills triple negative breast cancer cells, tumor cells in mice

A virus not known to cause disease kills triple-negative breast cancer cells and killed tumors grown from these cells in mice, according to Penn State College of Medicine researchers. Understanding how the virus kills cancer may lead to new treatments for breast cancer.

Adeno-associated virus... Read More

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