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Scientists Hit Antibiotic Pay Dirt Growing Finicky Bacteria In Lab

Scientists say they have discovered a natural compound from bacteria that may prove to be a potent new antibiotic. This news comes at a time when many current antibiotics are losing their oomph — germs become resistant to them.

The new compound is especially intriguing because it appears that... Read More

TWiM #95: A microbe lover in San Diego

Hosts: Vincent Racaniello.


Special guest: Stanley Maloy


Vincent meets up with Stan Maloy o... Read More

Op-Ed: Microbiology in the news, the top stories of 2014

London Colney - The website Pharmaceutical Microbiology has reviewed the top ten microbiology stories and events that have made the news during 2014.

Click "source" to read more.
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LD bodies inside a macrophage

A smear showing LD bodies inside a macrophage from a patient of Kala-azar visiting Universal College of Medical Sciences and Teaching Hospital. Photo Courtesy: Dr. Deliya Paudel, Department of pathology Read More

Swarming Motility/ Proteus mirabilis

A sample of Proteus mirabilis was inoculated on to a TSA plate by taking a sterile swab and placing a drop in the center of the plate. The plate was then incubated at 37 degrees for 8 hrs. Swarming motility can be seen as a clear halo and finger like projections coming from and around the grow... Read More

Unknown environmental Contaminant on blood agar plate streaked with S. pyogenes

A streak plate of Strep pyogenes on blood agar, stock culture used for class, was kept at room temp for 1 month. Before disposal a contaminant, presumably environmental, was seen on the plate. The pigment was opaque tan/yellow and with a mucoid surface. Lobate marigins with raised irregular-rh... Read More

TWiP 80: Daniel in the parasites' den

Vincent and Dickson welcome new TWiP host Daniel Griffin to discuss the association of a new Mycoplasma with trichomoniasis, and to introduce a new feature to the show, a case study.


Hosts: Vincent Racaniel... Read More

TWiP 80 letters

Jessica writes:


Hello Dr Racaniello and Despommier,


I recently saw an article about the paper linked below on Science Daily and thought it might be worth a discussion on TWIP. It is about the possibility of bed bugs being a vector for T. cruzi. I would love to... Read More

Cancer copies how healthy cells move to invade organs

To slip, slide, squeeze and otherwise invade different parts of the body, cancer cells learn to switch between two modes of moving usually used by healthy cells. Now we know how.

Click "source" to read more. Read More

Promising antibiotic discovered in microbial ‘dark matter’

An antibiotic with the ability to vanquish drug-resistant pathogens has been discovered — through a soil bacterium found just beneath the surface of a grassy field in Maine. Although the new antibiotic has yet to be tested in people, there are signs that pathogens will be slow to evolve resistan... Read More

An unexpected benefit of inactivated poliovirus vaccine

The polio eradication and endgame strategic plan announced by the World Health Organization in 2014 includes at least one dose of inactivated poliovirus vaccine (IPV). Since 1988, when WHO announced the polio eradication plan, it had relied exclusively on the use of oral poliovirus vaccine (OPV)... Read More

Seeking single cells’ secrets

The National Institutes of Health has awarded grants totaling $7.9 million in 2014 to 25 research teams who are unraveling the workings of single cells, as part of an effort to spur development of personalized treatments that target disease at the cellular level. The grants are supported by the ... Read More

Beta-hemolysis - Blood Agar

You can see clearly in this picture how the red cells are destroy by the bacteria, creating this amazing effect in the agar. What bacteria do you think it is?? Read More

‘PURE’ STEM CELLS LET MICE FIGHT OFF HIV

An improved gene therapy strategy using modified human stem cells shows promise in animal models as a functional cure for HIV.

Click "source" to read more. Read More

Why are bacteria all the same size

Just when we think we know everything, a story comes along to remind us that there is something fundamental--and seemingly elementary--that we still haven't figured out. “Why are we the size we are? Why are our organs the size they are? Why are the cells in those organs a stereotypical size? Wha... Read More

How bacteria control their size

Scientists have traditionally studied bacteria in large numbers, not individually. Working with tens of millions of cells in a culture flask, they tracked their growth by looking at how much the cells dimmed light passing through a tube.

Using this method, scientists learned that populations ... Read More

BacterioFiles 198 - Dampening Dust Defense

This episode: Modified probiotic bacteria could reduce life-threatening allergies!


(6.3 MB, 6.8 minutes)


Show notes: 
Journal ... Read More

Cholera Bacteria Spear Their Prey to Grab Genes

The bacteria that cause cholera grab genes from other organisms in a particularly predatory and precise way, new research finds: They spear neighboring cells with a kind of poison-tipped spike.

Bacteria often grab genes from other organisms and incorporate that DNA into their own genomes. But... Read More

Predicting superbugs' countermoves to new drugs

With drug-resistant bacteria on the rise, even common infections that were easily controlled for decades -- such as pneumonia or urinary tract infections -- are proving trickier to treat with standard antibiotics.

New drugs are desperately needed, but so are ways to maximize the effective lif... Read More

Compound keeps virus sealed in its "pocket"

A new class of compounds may be an effective way to fight a virus that leaves children with serious respiratory infections and might be associated with polio-like symptoms.

Researchers used a technique called X-ray crystallography to learn the precise structure of the original strain of enter... Read More
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