Plants and Microorganisms are the major sources of drugs till date. Most of these "natural products" come from a few genera of soil and marine bacteria that have long been known for their prolific chemistry. The classical process of discovering drugs from microorganisms have two drawbacks- it is... Read More
Picture carefully taken with my iphone under a dissecting microscope. Read More
Because viruses must bind to cell surface molecules to initiate replication, the use of soluble receptors to block virus infection has long been an attractive therapeutic option. Soluble receptors have been developed that block infection with rhinoviruses and HIV-1, but these have not been licen... Read More
An otherwise balanced review of selected aspects of Ebolavirus transmission falls apart when the authors hypothesize that ‘Ebola viruses have the potential to be respiratory pathogens with primary respiratory spread.’
The idea that Ebolavirus might become transmitted by the respiratory route ... Read More
Significant accumulations of polyphosphate granules have been found in three common sponge species of the Caribbean coral reef, indicating that microorganisms that live on marine sponges are pulling phosphorus out of the water to feed themselves and survive in a deep-water environment where very... Read More
Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows.
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The human body doesn’t like outsiders. When a foreign pathogen or substance, say an unwanted virus, finds its way into our blood streams we produce antibodies that the neutralize the threat. These “Y”-shaped proteins are made by a class of white blood cells called plasma cells and bind to molecu... Read More
The typical Escherichia coli, the laboratory rat of microbiology, is a tiny 1-2 thousandths of a millimeter long. Now, by blocking cell division, two researchers at Concordia University in Montreal have grown E. coli that stretch three quarters of a millimeter. That's up to 750 times their norma... Read More
A potentially life-threatening gastrointestinal infection is more common than previously estimated, federal health officials reported Wednesday.
The infection, caused by a bacterium known as Clostridium difficile, or C-diff, causes nearly 500,000 illnesses in the United States each year and k... Read More
New research that focuses on the mechanism by which Ebola virus infects a cell and the discovery of a promising drug therapy candidate is being published February 27, 2015, in the journal Science. Dr. Robert Davey, scientist and Ewing Halsell Scholar in the Department of Immunology and Virology ... Read More
Sexual biology may be the key to uncovering why Anopheles mosquitoes are unique in their ability to transmit malaria to humans, according to researchers at Harvard T. H. Chan School of Public Health and University of Perugia, Italy. Through analysis of 16 Anopheles genomes, they found that these... Read More
Although natural selection is often thought of as a force that determines the adaptation of replicating organisms to their environment, Harvard researchers have found that selection also occurs at the level of neurons, which are post-mitotic cells, and plays a critical role in the emergence of A... Read More
In one of the most comprehensive analyses of immune function performed to date, researchers analyzed blood samples from 105 sets of healthy twins. They measured immune cell populations and their chemical messengers—204 parameters in all—before and after participants received a flu shot. Differen... Read More