MicrobeWorld

A macrophage (pale brown) interacts with Borrelia cells (blue), the spirochete bacteria that cause Lyme disease. Although the outer membrane of Borrelia contains a strong antigen, the OspC protein, the bacterium successfully evades the human immune system by hiding out in places less accessible ... Read More

Patients in the UK have been enrolled into a trial to see if an engineered virus can be used to heal their damaged and struggling hearts. The trial will use a virus to introduce genetic material into heart muscle to reverse the organ's decline. The British Heart Foundation said the idea had "gre... Read More

In 2001, Kashefi and collaborators published an article in Applied and Environmental Microbiology reporting the surprising finding that several iron-reducing microbes can use gold as an electron acceptor for their respiration. These microbial alchemists included both mesophilic and thermophilic ... Read More

Bacteria that grows only on rocks in the Swiss Alps has helped researchers identify how alcohol might affect key brain proteins.

“Now that we’ve identified this key brain protein and understand its structure, it’s possible to imagine developing a drug that could block the binding site,” says ... Read More

The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say.

When immune cells recognize essential gut bacteria as foreign, inflammatory bowel disease such as ulcerative colitis and Crohn's disease can be ... Read More

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.

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They sweep. They swab. They sterilize. And still the germs persist.

In U.S. hospitals, an estimated 1 in 20 patients pick up infections they didn't have when they arrived, some caused by dangerous 'superbugs' that are hard to treat.

The rise of these superbugs, along with increased pressur... Read More

A protein known to be a key player in the development of Parkinson's disease is able to enter and harm cells in the same way that viruses do, according to a Loyola University Chicago Stritch School of Medicine study.

The protein is called alpha-synuclein. The study shows how, once inside a ne... Read More

This episode: Soil microbe has a good enzyme for degrading cyanide pollution!

Download Episode (4.2 MB, 4.5 minutes)

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Bacteria are all over us, inside and out. Jiri Hulcr recently found 1,458 species of bacteria "new to science" in a small sample of human belly buttons. What we know about our little passengers and how they affect our bodies is dwarfed by what we do not. That can be disconcerting to think about,... Read More

Pancreatic cancer is a dreadful disease. Even in rich countries, only about 4% of those diagnosed with it are still alive after five years. In America it is the third-most-common cause of cancer deaths among women, after lung and breast cancer; among men it is fourth, after lung, prostate and co... Read More

Hosts: Vincent Racaniello, Rich Condit, Read More

In its native state, according to the CDC, the H5N1 flu virus is highly contagious and is especially deadly to birds. Fortunately, few people have contracted this strain of flu as it's quite deadly in people as well. Luckily, there have been very few cases of transmission of the virus between pe... Read More

There’s been a recent surge in cases of the avian influenza A (H7N9) viral infection in China. As of this morning, there have been over a hundred reported cases and more than twenty deaths. The virus’ relatively sudden appearance in April, usually considered the end of flu season in the northern... Read More

A vaccine created to treat a gut bacteria common in children with autism could also help control some symptoms of the neural development disorder, according to new research published in this month’s edition of the journal Vaccine.

Researchers Brittany Pequegnat and Mario Monteiro of the Unive... Read More

Kal Penn has a pretty unusual resume: He has starred in Harold and Kumar, the most successful series of stoner movies made in the past decade; and has served in the White House as the Obama administration's liaison to youth. Now he's hosting a new show, The Big Brain Theory, on the Discovery Cha... Read More

The H7N9 strain of avian influenza is more lethal than the coronavirus that caused the global SARS outbreak in 2003, a National Taiwan University Hospital doctor said.

Citing a University of Hong Kong report, Huang Li-min, head of the hospital’s Department of Pediatric Infectious Diseases, sa... Read More

Researchers have confirmed that the A H7N9 bird flu virus, which began in February 2013, was transmitted from chickens at a wet poultry market to humans, according to a new study published in the The Lancet.

Wet markets, which are common in Asian countries, are live animal markets.

A H7N9 ... Read More

In this blog post, I describe a simple "colony transformation" experiment I have done with my freshman students, illustrating transformation, antibiotic resistance, and GFP. The visual aspects help drive home the points effectivel. Read More

Virologist Hilary Koprowski died on 11 April 2013 at the age of 96. His main accomplishments are nicely summarized in the New York Times, but for a more comprehensive overview of his life, I highly recommend his biography Listen to the Music by Roger Vaughan. I did not have many opportunities to... Read More