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Viral escape hatch could be treatment target for hepatitis E

The technique that the hepatitis E virus — an emerging liver virus historically found in developing countries but now on the rise in Europe — uses to spread could present a weak spot scientists can exploit to treat the disease, according to a new study.

Princeton University-led researchers re... Read More

ReSeqTB Data Platform now available to public

The Rapid Drug Susceptibility Testing Consortium (RDST), coordinated by the Critical Path Institute (C-Path) through the Critical Path to TB Drug Regimens (CPTR) initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB). ReSeqTB is a data-sharing platform an... Read More

Why hospital antibiotic management strategies do little to curb resistance

A generation ago, two antibiotic strategies known as cycling and mixing were employed to outwit bacteria. Cycling is like antibiotic crop rotation where certain classes of antibiotics are withdrawn for a period of time. Doctors thought this would combat resistance because bacterial pathogens wou... Read More

New dental implant with built-in reservoir reduces risk of infections

A multidisciplinary team of researchers at KU Leuven (University of Leuven, Belgium) has developed a dental implant that gradually releases drugs from a built-in reservoir. This helps prevent and fight infections.

Our mouth contains many micro-organisms, including bacterial and fungal pathoge... Read More

Meet your Microbes (video)

They’re on your tongue, under your armpits, in your guts and on your skin. In fact, any place you can think of there are microbes living on, under, or in between there. In their unimaginably large numbers, these micro-organisms determine our lives – even though we never see them. Micropia, the w... Read More

Researchers Use Innovating Methods to Study Vertical Transmission of Microbes

It has been assumed that mothers pass on gut microbes to their infants during and just after delivery, a process called vertical transmission, but because of technical restraints, the evidence of this occurring has been limited. Previous cultivation-free studies have observed the same microbial ... Read More

Better Diagnosis of Fungal Infections Key to Reducing Antibiotic Resistance

Poor diagnosis worldwide of fungal disease causes doctors to overprescribe antibiotics, increasing harmful resistance to antimicrobial drugs, according to a paper published today in Emerging Infectious Diseases.

“Inadequate attention is paid to fungal infection as the cause of antibacterial t... Read More

UV light can aid hospitals' fight to wipe out drug-resistant superbugs

A new tool -- a type of ultraviolet light called UVC -- could aid hospitals in the ongoing battle to keep drug-resistant bacteria from lingering in patient rooms and causing new infections.

Some hospitals have already begun using UVC machines in addition to standard chemical disinfection to k... Read More

HIV therapy could be contributing to syphilis outbreak: UBC study

Drugs used to treat HIV could affect how the body responds to syphilis, inadvertently contributing to a current outbreak, a new study suggests.

In this study, researchers investigating the outbreak hypothesize that medications used in highly active antiretroviral therapy (HAART), the gold sta... Read More

Penn study identifies potent inhibitor of Zika entry into human cells

A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types, was discovered by researchers from the Perelman School of Medicine at the University of Pennsylvania. Publishing in Cell Reports t... Read More

Advancing Phage Therapy

New research conducted at the University of Miami in Coral Gables, Florida and the National Cancer Institute, in Bethesda, Maryland demonstrate that a subset of bacteriophages, dubbed “superspreaders,” potentially play a major role in transmitting antimicrobial resistance. The research, describe... Read More

Innovative Chemical Treatments to Kill Foodborne Pathogens - Michael Doyle, PhD

Michael Doyle, PhD, Regents Professor of Food Microbiology at the University of Georgia's College of Agricultural and Environmental Sciences, discusses a variety of alternative food preservatives which can prevent unintended contamination of foods by pathogens and spoilage microbes.

ASM’s vir... Read More

Emerging Pathogen Surveillance with Jonna Mazet, PhD

Jonna Mazet, PhD, UC Davis School of Veterinary Medicine, is interviewed by Vincent Racaniello, PhD, Columbia University, New York, about emerging pathogen surveillance and public health. Dr. Mazet is the Principal Investigator and Global Director of the novel viral emergence early warning proje... Read More

Building an Ebola Virus Lab in Sierra Leone with Ian Goodfellow, PhD

Ian Goodfellow, PhD, Cambridge University, is interviewed by Vincent Racaniello, PhD, Columbia University, New York, about state of lab capacity in Africa during the Ebola outbreak. Goodfellow made the decision to go to Sierra Leone during the late summer of 2014 after following the media covera... Read More

Bacteria Inagaration

Micrococcus luteus/lylae (hair), Staphylococcus epidermidis (shirt, teeth), and Kocuria rosea (skin) on tryptic soy agar. #agarart Read More

BacterioFiles 282 - Mycobacteria Make Mice Mellow

This episode: Vaccinating mice with heat-killed soil bacteria reduced their stressed behavior and inflammation!


(9.8 MB, 10.7 minutes)


Show notes: 


Journal Paper:

Reber SO, Siebler PH, Donner NC, Morton JT, Smith ... Read More

TWiV 424: FLERVergnügen

Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago.


Hosts:  Read More

The super Bug from Moldova

It is very sad to watch how these small bodies are each year stronger and resistant to antibiotics. Read More

Outbreak of H7N2 Flu in Cats

Many mBiosphere readers will know that the influenza A virus infects multiple species, and this ability to infect birds, humans, and other mammals such as pigs is one of the ways virions can exchange genetic information, leading to new viruses able to cause major outbreaks. However, few mBiosphe... Read More

Peanuts and Probiotics

The world has a problem: an exploding human population, which will require crop yields to double by 2050 without increasing crop acreage. Solving this problem will necessitate help from some of the smallest members of Earth’s population using a concept that has both George Washington Carver and ... Read More
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