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TWiM #122: Mayonii, microRNAs and the microbiome

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.


Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome. Read More

TWiM 122 Letters

Hunter writes:


Greetings TWiM crew!
 
I recently learned of a new game (currently getting ready for Alpha and crowd funding) where players will edit microbes at the genetic level and pit them against microbes created by other players. The game is called... Read More

Genomic sequencing reveals link between STIs and leading cause of infectious blindness

For the first time, genome sequencing has been carried out on Chlamydia trachomatis (C. trachomatis), a bacteria responsible for the disease Trachoma - the world's leading infectious cause of blindness, according to a study in Nature Communications. Read More

Zika epidemic highlights need for priority vaccine research for pregnant women

The recent outbreak of Zika virus disease and its link to fetal development highlights the need for pregnant women and those of reproductive age to be a priority group for developing and evaluating new vaccines and vaccine guidelines for Zika and other emerging infectious diseases, say the autho... Read More

Register now for FREE webinar "The Secret Life of Microbes In and Around Our Homes" on Mar 10

Join Noah Fierer, CU Assoc. Professor & CIRES Fellow, as he shares insights from his team's explorations into the distribution and roles of microscopic organisms in diverse environments, including our homes. Noah will discuss how the location, occupants, and house design shapes the types of micr... Read More

mSystems video introduction: ADAGE-based integration of gene expression datasets

First mSystems video introduction of a recently published article from Casey Greene's lab Read More

mSystems video introduction, or: The tl;dr version for ADAGE-based integration of gene expression datasets

We at mBiosphere know you are busy, reader! With various gels, analyses, programs, and classes to run, not to mention reports, abstracts, and grants to write, we know there are many demands made on our readers’ time (plus, dinner to plan, laundry to fold, the dog to walk...wait! Don't go! You ha... Read More

Stress wakes up sleeping herpesviruses -- but how?

Hiding their DNA genome inside the nucleus of the infected cells, the herpesviruses establish a lifelong infection in humans. Not well defined stress conditions are known to wake up these parasites from their dormancy - the latent phase - and reactivate the production of new viral progeny, event... Read More

Ebola survivor study yields insights on complications of disease

Preliminary findings from PREVAIL III, a study of Ebola virus disease (EVD) survivors being conducted in Liberia, indicate that both Ebola survivors and their close contacts have a high burden of illness. However, the prevalence of eye, musculoskeletal, and neurological complications was greater... Read More

Applications of Clinical Microbial Next-Generation Sequencing - American Academy of Microbiology

The American Academy of Microbiology hosted an event at the National Press Club in February 2016 to disseminate the report, "Applications of Clinical Microbial Next-Generation Sequencing".

A panel of 4 speakers discussed real world applications of NGS and findings from the report, followed b... Read More

The Bacteria Song by the Science Pirates

Science Pirates Songs presents the Bacteria Song by New Mexico State University 2003. These animated songs are from the adventure learning game, 'Science Pirates: The Curse of Brownbeard', which guide middle school students through concepts in both science and food safety. Read More

Newly discovered HIV genome modification may put a twist on vaccine and drug design

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016... Read More

First hospital-based rapid detection Zika test now available

Collaboration between two Texas Medical Center institutions has resulted in today's release of the country's first hospital-based rapid tests for the Zika virus. Read More

New bat gammaherpesvirus may help understand bats' role in zoonoses

Many emerging viruses (such as SARS-CoV, Ebola virus, and the Henipavirus genus) are thought to have zoonotic reservoirs in the regional bat populations. Bats offer a threat to spreading these viruses because their flight capacity makes them readily mobile. Also, there are a whole lot of them: w... Read More

TWiV 377: Chicken with a side of Zika

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiEVO 5: Looking at straw colored fruit bats through a straw

We have some virology for you on the latest episode of the science show This Week in Evolution. Nels and I are joined by Kartik Chandran and Sara Sawyer who talk about their work showing how the filovirus receptor NPC1 controls susceptibility of bats to Ebolavirus infection. They have found that... Read More

3-D protein map offers new malaria vaccine hope

A three-dimensional 'map' of a critical protein that malaria parasites use to invade human red blood cells could lead to a vaccine countering the most widespread species of the parasite. Read More

Ebola crisis provides framework for responding to outbreaks like Zika virus

PRINCETON, N.J.--As world leaders grapple with containing the Zika virus, the Ebola epidemic in West Africa provides valuable lessons for how to respond to infectious disease epidemics, according to a policy report published by researchers at Princeton University and the Wellcome Trust. Read More

New American Academy of Microbiology Report provides recommendations for implementing NGS to clinical microbiology settings

This morning, the American Academy of Microbiology released a report, “Applications of Clinical Microbial Next-Generation Sequencing.” An event was held at the National Press Room to highlight its release. You can read more about the event here, or go here to read recommendations on NGS in a cli... Read More

Acid-fast bacilli

Acid-fast bacilli in auramine rhodamine stain. Read More
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