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Bat SARS-like coronavirus: It’s not SARS 2.0!

A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More

TWiV 340: No shift, measles

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 342: Public epitope #1

 Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

BacterioFiles 248 - Tiny Travelers Transport Toxin Trashers

This episode: Bacteria that swarm around in groups carry other bacteria with them that can be helpful for degrading toxins!


(14.2 MB, 15.5 minutes)


Show notes: 
Read More

Ebola medical team develops guidelines for treating infected children

When the Ebola virus outbreak erupted in West Africa in 2014, children infected with the virus -- particularly those under age 5 -- faced overwhelming challenges. Not only was there a high death rate among young children infected with the disease, they often were isolated from their families, le... Read More

A new approach to predict evolution of influenza viruses can enhance vaccine efficacy

New results from a study performed at the University of Helsinki suggest that genomic information from circulating influenza viruses can help in producing more efficient seasonal vaccines. The researchers were able to develop a simple approach for reliable real-time tracking and prediction of vi... Read More

MGH team broadens utility of more compact CRISPR-Cas9 by increasing its targeting range

A team of Massachusetts General Hospital (MGH) investigators has shown that a method they developed to improve the usefulness and precision of the most common form of the gene-editing tools CRISPR-Cas9 RNA-guided nucleases can be applied to Cas9 enzymes from other bacterial sources. In a paper r... Read More

Insecticide-treated nets may still prevent malaria despite mosquito resistance

Insecticide-treated nets may still help prevent malaria despite mosquitoes developing resistance, according to a new study published in Parasites & Vectors. Read More

BacterioFiles 249 - Spores Survive Spaceship Scorching

This episode: Bacterial spores can survive atmospheric entry on an artificial meteorite!


(10.7 MB, 11.25 minutes)


Show notes: 
J... Read More

Microorganisms Spreading Holiday Cheer

This holiday season, as you open a bottle of your favorite wine to share with family and friends, consider making a toast to Saccharomyces cerevisiae (also known as “brewer’s yeast”) which is a species of yeast that is commonly used for making wine and beer. Yeast is absolutely essential to wine... Read More

Latest technology could help curb repeat Ebola crisis, experts say

Recent developments in surveillance technology could enable a swifter, more effective response to potentially deadly outbreaks of disease, a study has found. Read More

TWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.


Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. E... Read More

New gene a key to fighting sepsis

Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis. Read More

TWiM 112 Letters

Steve writes:


Mysterious fungus killing snakes in NY, at least 8 other states | wivb.com - http://wivb.com/2015/08/10/mysterious-fungus-killing-snakes-in-ny-at-least-8... Read More

CRISPR/Cas9 used for rapid functional study of cancer-causing genes

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their ca... Read More

ROVING GENE LETS BACTERIA RESIST ‘LAST’ ANTIBIOTICS

A gene that lets bacteria resist polymyxins—the last line of antibiotic defense we have left—has shown up in widespread bacteria samples from pigs and patients in south China, including strains with epidemic potential. Read More

Vitamin C can be Helpful in Improving Blood Vessel Constriction

BOC Sciences-Latest study on vitamin C shows that it can play a positive role in improving blood vessel constriction with almost equal effect as walking. In the study, the exercise of a protein which is the main factor of blood vessel constriction was compared with the effect of vitamin C on bl... Read More

Methylobacterium aquaticum strain NO00 the guardian of rice

Methylobacterium aquaticum strain NO00 (KR920749) grown over rice grain. It can produce phytohormones and other beneficial metabolites for the plant. M. aquaticum is a plant growth promoting (PGP) bacteria". Its pink-biofilm, can help with water-stress and protect the plant against pathogens. Read More

Lingering lymphocytes lash out against Leishmania

Immune cells that hang around after parasitic skin infection help ward off secondary attack, according to a study in The Journal of Experimental Medicine. These skin squatters may prove to be the key to successful anti-parasite vaccines. Read More

New Drug for Chemotherapy Induced Vomiting and Nausea Was Approved by FDA

BOC Sciences-Varubi also named as rolapitant, gained approval from FDA. And it’s said the drug went into its third phase clinical trial. Till now about 2800 patients have involved in the trial. Read More
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