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New promise for treatment of enterovirus infection

Feeling a bit under the weather? There’s a decent chance you’re suffering from an infection with an enterovirus. Enteroviruses are a commonly encountered virus, especially in the summer and fall. They can cause a variety of symptoms, from cold-like symptoms such as runny nose or fever to more se... Read More

Microbial Conversations: A free ASM public science event @ the MIT Museum THIS SATURDAY, June 18!

Whether you're in town for ASM Microbe 2016 and looking for something to do with friends or family, or you're local to the Boston-area, come out to our "Microbial Conversations" public science event at the MIT Museum! Join us for short, sharp conversations about a variety of topics in microbiolo... Read More

Researcher pioneers bacterial infection treatment using novel target: Vesicles

Bacterial infection takes hold in the body when a pathogenic microorganism delivers toxins to healthy cells. One way bacteria accomplish this is by releasing vesicles, which act as tiny envelopes transporting toxins and other virulence factors to host cells. These toxins allow the bacteria to "m... Read More

FDA-approved drug protects mice from Ebola

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers a... Read More

Student Thoughts On The First Day of Microbiology Class

I teach Microbiology at the University of Puget Sound every fall semester. The swiftly changing field of microbiology has depth and breath...and I was interested to learn what my students thought of the topic at the beginning of the first day of class. We will revisit this subject at the end o... Read More

Impact of climate change on parasite infections depends on host immunity

New research demonstrates how climate change and the immune reaction of the infected individual can affect the long-term and seasonal dynamics of parasite infections. The study, led by Penn State University scientists, assessed the infection dynamics of two species of soil-transmitted parasites ... Read More

Anti-bacterial fabric holds promise for fighting superbug

Antibiotics have proven to be a valuable weapon in the fight against infectious bacteria. However, due to the excess use of antibiotics in conventional treatments, overtime antibiotics have become less effective. Read More

People with rage disorder twice as likely to have latent toxoplasmosis parasite infection

Individuals with a psychiatric disorder involving recurrent bouts of extreme, impulsive anger--road rage, for example--are more than twice as likely to have been exposed to a common parasite than healthy individuals with no psychiatric diagnosis. Read More

TWiV 405: All the world's a phage

The TWiXers discuss a study on vertical transmission of Zika virus by Aedes mosquitoes, and uncovering Earth's virome by mining existing metagenomic sequence data.

Hosts: Vincent Rac... Read More

Antibiotic stewardship - a community effort

As we highlighted in our previous blog, antibiotic stewardship – the careful use of appropriate antibiotic administration – can have positive effects. A small change from a difference in clinical lab reporting led to less drug use, which led to fewer drug-resistant infections. When we think of a... Read More

A cultural revolution in the study of the gut microbiome

(BOSTON) - It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst can lead to life-threatening complications. While abnormal imm... Read More

TWiV 402: The plight of the bumblebee

Polio returns to Nigeria, Zika virus spreads in Miami, and virus infection of plants attracts bumblebees for pollination, from the virus gentlepeople at TWiV.

Hosts: Vincent Racaniello Read More

Ancient clay remedy proves its antibacterial powers in the lab

Near Kisameet Bay on the central coast of British Columbia sits a deposit of clay that covers 5 acres and spans a depth up to 42 feet in places. This vast smear formed 10,000 years ago as glacial melt filled a granite basin and fine minerals silted out.

The ancient clay likely holds secrets t... Read More

Microbial Identification and Tracking: the Next Generation

How do you identify an unknown microbe? If you’ve taken an introductory microbiology lab course in the past twenty years, chances are you were assigned an unknown bacterium that you had to identify through differential media and biochemical assays. Newer techniques like qPCR are being standardiz... Read More

Study reveals how herpes virus tricks the immune system

With over half the U.S. population infected, most people are familiar with the pesky cold sore outbreaks caused by the herpes virus. The virus outsmarts the immune system by interfering with the process that normally allows immune cells to recognize and destroy foreign invaders. How exactly the ... Read More

Microbiology Myths Debunked: Scientific Analysis of the Five Second Rule

While walking through your house, you drop a granola bar you were eating. Quick – do you pick it up and eat it? Is the ground too dirty to eat from? Does the amount of time the food sits on the ground matter? Will more microbes gather onto the snack as you decide whether or not to continue noshi... Read More

The classic and current studies of bacterial endospore morphology

Recently, one of the Journal of Bacteriology Classic Spotlight series highlighted the numerous studies on bacterial spores that have been published in the journal throughout the years. Bacterial endospores, the resilient and relatively quiescent bacterial structures first identified in the 1800s... Read More

Moving to Zika Virus

I have worked on polio virus in my laboratory at Columbia University for 35 years. When that virus is eradicated--perhaps in the next few years--we will have to destroy all of our virus stocks. When that happens, I can either go home, or find another virus.

When Zika virus stepped into the w... Read More

3-D protein map offers new malaria vaccine hope

A three-dimensional 'map' of a critical protein that malaria parasites use to invade human red blood cells could lead to a vaccine countering the most widespread species of the parasite. Read More

Using TALEs to turn off any gene in E. coli

UW-Madison researchers engineered TALEs to transcriptionally repress any gene in E. coli. The results, published in Nature Chemical Biology, offer a new way to fine-tune bacterial physiology. Although TALEs have long been used for gene editing or transcriptional activation, this is one of the fi... Read More
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