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Register now for FREE Microbes and the Miracle of Compost Tea webinar on Jan. 14

Click the above "source" link to register: http://cires.colorado.edu/education-outreach/events/test-event/?eID=409

Join us to learn how and why microbes are the natural secret to a healthy soil environment in growing lush lawns and abundant gardens. The science behind soil microbes and tips o... Read More

A biofilm model that accounts for cell aggregates

Whether you’ve Google-searched “biofilm” to learn more yourself, taken courses covering the subject, or are deeply embedded in biofilm-related research, you’ve probably encountered a model similar to the one below, which represents biofilm maturation. In the current model, a biofilm begins with ... Read More

Study Shows How Bacteria Evolve in the Lungs of Cystic Fibrosis Patients

Washington, DC – May 24, 2016 – The bacterium Burkholderia multivorans evolves and adapts in bursts to survive in the lungs of cystic fibrosis patients, according to a study published this week in mSystems, an open access journal from the American Society for Microbiology. The work, believed to ... Read More

TWiM 126 Letters

 


Anthony writes:
An Abandoned Sailor’s Infirmary in NYC Where Cholera Bacteria Was Discovered
http://untappedcities.com/2016/03/... Read More

Scientists are Working on Making Drugs More Biodegradable

BOC Sciences-Wild animals were found carrying drug resistance though they are living in areas where few human activities are existing. This finding makes scientists think about how to prevent the situation from deteriorating and protect water from being polluted furtherly. From the previous blog... Read More

New gene a key to fighting sepsis

Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis. Read More

Study finds that Ebola vaccine is safe and stimulates strong immune response

Baltimore, MD, November 17, 2015--A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, Wes... Read More

MGH team broadens utility of more compact CRISPR-Cas9 by increasing its targeting range

A team of Massachusetts General Hospital (MGH) investigators has shown that a method they developed to improve the usefulness and precision of the most common form of the gene-editing tools CRISPR-Cas9 RNA-guided nucleases can be applied to Cas9 enzymes from other bacterial sources. In a paper r... Read More

New American Academy of Microbiology Report provides recommendations for implementing NGS to clinical microbiology settings

This morning, the American Academy of Microbiology released a report, “Applications of Clinical Microbial Next-Generation Sequencing.” An event was held at the National Press Room to highlight its release. You can read more about the event here, or go here to read recommendations on NGS in a cli... Read More

Preclinical Studies on the Pharmacokinetics, Safety, and Toxicology of Oxfendazole: Toward First in Human Studies

A number of BZ anthelmintics used in veterinary medicine have been considered for transition to human use, including oxibendazole and oxfendazole (OXF). In addition, flubendazole, already approved for use as an intestinal anthelmintic, is also being developed as a treatment against adult filaria... Read More

Latest technology could help curb repeat Ebola crisis, experts say

Recent developments in surveillance technology could enable a swifter, more effective response to potentially deadly outbreaks of disease, a study has found. Read More

Stress wakes up sleeping herpesviruses -- but how?

Hiding their DNA genome inside the nucleus of the infected cells, the herpesviruses establish a lifelong infection in humans. Not well defined stress conditions are known to wake up these parasites from their dormancy - the latent phase - and reactivate the production of new viral progeny, event... Read More

Pseudomonas aeruginosa with pyoverdine extracellular pigment

This strain of Pseudomonas aeruginosa isolated from wound make a green pigment: pyoverdine. Pyoverdine is a fluorescent siderophores for to acquire iron.
Pyoverdine biosynthesis in Pseudomonas aeruginosa and fluorescent Pseudomonads is a complex process.

Credits: dr. Francesco d'Aleo & Robe... Read More

Vitamin C can be Helpful in Improving Blood Vessel Constriction

BOC Sciences-Latest study on vitamin C shows that it can play a positive role in improving blood vessel constriction with almost equal effect as walking. In the study, the exercise of a protein which is the main factor of blood vessel constriction was compared with the effect of vitamin C on bl... Read More

CRISPR/Cas9 used for rapid functional study of cancer-causing genes

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their ca... Read More

What effect does environmental temperature have on bacterial virulence?

A recent tragic die-off of saiga antelope has scientists puzzled about what could cause such a sudden, drastic, large-scale death. Infectious disease could easily be playing a part, with Pasteurella multocida and Clostridium perfringens both possible candidates found in animal necropsies. The su... Read More

Less effective antimalarial therapies can help fight malaria better

Oxford University scientists have found that the more effective way to beat malaria is to use less effective drugs some of the time. Read More

Microbial communication over the airwaves

Jean-Paul Latgé originally wanted to know if he could test the breath of patients with Aspergillus infections for volatile compounds produced by the fungus. His group at the Pasteur Institute in Paris thought this might be a new way of diagnosing fungal culprits like Aspergillus fumigatus that o... Read More

Urinary tract infection: How bacteria nestle in

Almost every second woman suffers from a bladder infection at some point in her life. Also men are affected by cystitis, though less frequently. In eighty percent of the cases, it is caused by the intestinal bacterium E. coli. It travels along the urethra to the bladder where it triggers painful... Read More

Using citizen science to engage students

Scientists and science educators now recognize the value in explaining what fields don’t understand, in addition to facts supported by years of experimental data. Citizen science projects, which emphasize accessibility of scientific technologies and methods for everyone, allow people without yea... Read More
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