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Some vaccines support evolution of more-virulent viruses

Scientific experiments with the herpesvirus such as the one that causes Marek's disease in poultry have confirmed, for the first time, the highly controversial theory that some vaccines could allow more-virulent versions of a virus to survive, putting unvaccinated individuals at greater risk of ... Read More

New Technique Could Prevent Biofilms on Catheters and Medical Implants

Washington, DC – October 30, 2015 – Biofilms—mats of bacteria similar to the plaque that grows on teeth—frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can threaten lives or lead to failure of the implants. Antibiotics are impotent against b... Read More

Five minutes basic lab training

This basic lab-training image was captured from the wall sticker of Clinical Microbiology Laboratory, Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Read More

Malaria's key to the liver uncovered

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease. Read More

Vincent van Gogh's "The Starry Night" #agarart2015

While not original art, it’s still a fun piece. BBL’s CHROMagar Orientation agar is the canvas for this piece of agar art. Chromogens in the agar release a colored compound when hydrolyzed by specific enzymes allowing certain bacteria to appear different colors on it. The brown color is Proteus... Read More

Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More

$7 million grant aids efforts to eliminate neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received a $7 million grant from the Bill & Melinda Gates Foundation aimed at eliminating river blindness and elephantiasis, two neglected tropical diseases that annually sicken millions. Read More

TWiM 104 Letters

Mark writes:

Hello TWiM-aggregate,

Its warm and sunny Spring weather here in California’s Bay Area. The fourth year
of Drought is upon us - please send water.

Speaking of water, below is a humorous incident that could be used to draw
attentio... Read More

TWiM 98 Letters


Patrick writes:

Hi Vincent,

I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More

TWiV 326: Giving HIV a flat tyr

Hosts: Vincent RacanielloAlan Dove, and  Read More

My first "Mu-Tube" video promoting microbial literacy: What does "microbiology" mean to students?

For my Microbiology course at the University of Puget Sound, I decided to ask my new crop of "micronauts" what the word "microbiology" meant to them on the first day of class. Here are their answers. My wife Jennifer Quinn and I put this together using art from former students. Hopefully, thi... Read More

TWiV 316: The enemy of my enemy is not my friend

Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.

Hosts: Vincent Racaniello Read More

TWiP 80 letters

Jessica writes:

Hello Dr Racaniello and Despommier,

I recently saw an article about the paper linked below on Science Daily and thought it might be worth a discussion on TWIP. It is about the possibility of bed bugs being a vector for T. cruzi. I would love to... Read More

Scientists are Working on Making Drugs More Biodegradable

BOC Sciences-Wild animals were found carrying drug resistance though they are living in areas where few human activities are existing. This finding makes scientists think about how to prevent the situation from deteriorating and protect water from being polluted furtherly. From the previous blog... Read More

'Ensemble' modeling could lead to better flu forecasts, study finds

By combining data from a variety of non-traditional sources, a research team led by computational epidemiologists at Boston Children's Hospital has developed predictive models of flu-like activity that provide robust real-time estimates (aka "now-casts") of flu activity and accurate forecasts of... Read More

TWiM #115: Profiling the Poglianos

Host: Vincent Racaniello

Special guests: Kit Pogliano and Joe Pogliano

Vincent visits the laboratories of Kit and J... Read More

Paper-based test can quickly diagnose Ebola in remote areas (video)

BOSTON, Aug. 18, 2015 -- When a fever strikes in a developing area, the immediate concern may be: Is it the common flu or something much worse that requires quarantine? To facilitate diagnosis in remote, low-resource settings, researchers have developed a paper-based device that changes color, d... Read More

Yellow Unknown Yeast

Unknown yeast isolated on TSA from a swab taken from the bottom of a shoe incubated at 25 degrees C. Yellow, mucoid, round colonies were seen after 2 weeks. This isolate grew equally well at 37 degree C with a growth time of ~ 1 week. Read More

Guinea reports Ebola-free week, but Sierra Leone has 5 cases

For the first time in more than a year, Guinea passed a week without a new lab-confirmed Ebola case, but the news out of West Africa last week was tempered by a flare-up of activity in Sierra Leone, the World Health Organization (WHO) reported today in its latest update. Read More

High containment: inside the £145M virus lab

Ever wondered what considerations go into a brand new £145M virus research laboratory? The new award-winning building at The Pirbright Institute has taken some brave and bold steps in design to contain high-risk microbes. High containment labs are usually buried deep inside a building to keep da... Read More
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