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The Wall of Polio, version 3.0

Back in 2013 I built a Wall of Polio in my laboratory – a large stack of six-well cell culture plates that have been used to measure the concentration of polioviruses in various samples by plaque assay. It became a focal point of the lab at which many guests came to have their photographs taken.... Read More

Bacterial Enzyme is Found for a Medical Way of Smoking Cessation

BOC Sciences-There is a new species of bacteria found by scientists from The Scripps Research Institute (TSRI) for a kind of enzyme it produces that can be used as an interfering substance to achieve smoking cessation. This finding will be smokingof considerable significance for its effectivenes... Read More

Lactose fermenting E.coli after overnight growing on MacConkey agar

MacConkey agar plate with invasive lactose fermenting E.coli which was isolated for fatal case of neonatal septicemia.
Photo was taken after 12h incubation under 37C.
Credits: Povilas Kavaliauskas, Vilnius University, Lithuania. Read More

TWiV 366: Doctorates down under

Host: Vincent Racaniello


Guests: Carla Giles, Zoe Dyson, Brianna McLean, and Caitlin O'Brien


In Melbourne, Australia, Vincent speaks with four PhD students about their research projects and what... Read More

Newton Fund grant to aid researchers in tackling infectious disease in Malaysia

A group of collaborators led by the University of Southampton have been awarded a British Council Newton Fund Institutional Links Grant to support ground-breaking research towards reducing the burden of infectious disease in Malaysia. Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

ANTIBIOTICS DON’T POP BACTERIA LIKE A BALLOON

The days when antibiotics worked reliably and scientists could assume they worked directly—like popping a balloon—are fading. As resistance mounts, understanding how antibiotics really work could be the key to sustaining their efficacy. Read More

Powerhouse in your mouth

According to the American Academy of Implant Dentistry, two in three Americans have one or more missing teeth. To deal with this issue, American dentists perform more than five million dental implants a year. About 1% to 15% of the patients receiving implants experience dental implant failure ... Read More

Scripps research-designed drug candidate significantly reduces HIV reactivation rate

HIV-infected patients remain on antiretroviral therapy for life because the virus survives over the long-term in infected dormant cells. Interruption of current types of antiretroviral therapy results in a rebound of the virus and clinical progression to AIDS. Read More

Expression of a single gene lets scientists easily grow hepatitis C virus in the lab

Worldwide, 185 million people have chronic hepatitis C. Since the late 1980s, when scientists discovered the virus that causes the infection, they have struggled to find ways to grow it in human cells in the lab -- an essential part of learning how the virus works and developing new effective tr... Read More

Streptomyces albus

Streptomycetes are a member actinomycete family. Streptomycetes are usually found in soil and are important decomposers. They are aerobic, gram-positive, filamentous rods that create branching hyphae. They also produce more than half of the world's antibiotics, and are therefore very valuable in... Read More

Virus-like particle vaccine protects mice from many flu strains

A vaccine that protects against a wide variety of influenza viruses (a so-called universal flu vaccine) is a critical public health goal given the significant rates of illness and death caused by seasonal influenza and the potentially devastating effects of a pandemic influenza strain. Now, rese... Read More

Romidepsin can reverse HIV latency in patients on long-term ART

A cure for HIV requires the eradication of latent (i.e., dormant and therefore hidden) virus from reservoirs in immune cells throughout the body. HIV latency depends on the activity of proteins from the human host called histone deacetylases (HDAC), and previous work has shown that HDAC inhibito... Read More

Single dose Ebola vaccine is safe and effective in monkeys against outbreak strain

National Institutes of Health (NIH) scientists report that a single dose of an experimental Ebola virus (EBOV) vaccine completely protects cynomolgus macaques against the current EBOV outbreak strain, EBOV-Makona, when given at least seven days before exposure, and partially protects them if giv... Read More

Researchers develop world's most sensitive test to detect infectious disease, superbugs

Infectious diseases such as hepatitis C and some of the world's deadliest superbugs--C. difficile and MRSA among them--could soon be detected much earlier by a unique diagnostic test, designed to easily and quickly identify dangerous pathogens. Read More

A Toxic Chemical Compound Will be Generated in the Roaster Process of Coffee Beans

BOC Sciencs-Scientists found that a common food additive diacetyl can bring great damage to lungs when it be inhaled. And workers who roast coffee beans and make popcorn have frequent contact with the substance, that's one of the main reason that workers at these post will contract serious lung ... Read More

Partnership to develop production system for exciting new antibiotic

Researchers from Plymouth University are collaborating with world-leading industrial biotechnology and synthetic biology business Ingenza, to develop an efficient, scalable microbial production system for epidermicin, a new class of antibiotic being developed for use in the fight against infecti... Read More

Why do we still use Sabin poliovirus vaccine?

The Sabin infectious, attenuated poliovirus vaccines are known to cause vaccine-associated paralysis in a small number of recipients. In contrast, the Salk inactivated vaccine does not cause poliomyelitis. Why are the Sabin vaccines still used globally? The answer to this question requires a bri... Read More

Likely Drug Interactions In Placenta Could Harm Fetus

Washington, DC - October 13, 2015 - To date, studies in pregnant women examining transport of drugs across the placenta are rare and inadequate, said Tomo Nabekura, PhD. Such knowledge could be vital to preserving fetal health. In a new laboratory study, Nabekura and colleagues have illuminated ... Read More
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